Classification based Integration of Quantifications for LC-MS Analysis

doi:10.1109/SPAC46244.2018.8965613

UM > Faculty of Science and Technology > DEPARTMENT OF COMPUTER AND INFORMATION SCIENCE

Status	已發表Published
	Classification based Integration of Quantifications for LC-MS Analysis
	Li，Tianjun; Chen，Long; Wei，Huiqin
	2018-12-01
Source Publication	2018 International Conference on Security, Pattern Analysis, and Cybernetics, SPAC 2018
Pages	97-102
Abstract	A classification based integration of quantification method for the Liquid Chromatography - Mass Spectrometry (LC-MS) analysis is described in this paper. Typically, one biological tissue may be sent to the LC-MS many times in practice to generate multiple LC-MS data. Due to the precise level or the profile of the search engine, these multiple individual quantitative results of the multiple LC-MS data may be partially identical. Here we proposed a method to integrate the quantitative results for the case where there are multiple individual measurements but the results are only partially identical. This proposed method applies a classifier to the peptides and treats the predicted probabilities of the classification as the weights to combine these multiple individual quantitative results into a better one. Experimental results show that in the task of quantitative LC-MS, the results generated by this integration method perform better than the ones produced by other individual measurements.
DOI	10.1109/SPAC46244.2018.8965613
URL	View the original
Language	英語English
Scopus ID	2-s2.0-85079175561
Fulltext Access	View Full-Text via DOI View Full-Text via Scopus
Citation statistics
Document Type	Conference paper
Collection	DEPARTMENT OF COMPUTER AND INFORMATION SCIENCE
Affiliation	University of Macau,Department of Computer and Information Science,Taipa,Macao
First Author Affilication	University of Macau
Recommended Citation GB/T 7714	Li，Tianjun,Chen，Long,Wei，Huiqin. Classification based Integration of Quantifications for LC-MS Analysis[C], 2018, 97-102.
APA	Li，Tianjun., Chen，Long., & Wei，Huiqin (2018). Classification based Integration of Quantifications for LC-MS Analysis. 2018 International Conference on Security, Pattern Analysis, and Cybernetics, SPAC 2018, 97-102.

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