Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex

doi:10.1021/acsami.5b01702

UM > Institute of Chinese Medical Sciences

Residential College	false
Status	已發表Published
	Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex
	Lu L.1; Wang M.1; Liu L.-J.2 ; Leung C.-H.2 ; Ma D.-L.1,3
	2015
Source Publication	ACS Applied Materials and Interfaces
ISSN	1944-8244
Volume	7 Issue:15 Pages:8313
Abstract	A library of six luminescent Ir(III) complexes were synthesized and studied for their capacity to function as probes for G-quadruplex DNA. The novel Ir(III) complex 1 was discovered to be selective for G-quadruplex structures and was subsequently used for the construction of a label-free G-quadruplex-based ochratoxin A (OTA) sensing platform in aqueous solution. The assay exhibited linearity for OTA in the range of 0 to 60 nM (R2 = 0.9933), and the limit of detection for OTA was 5 nM. Furthermore, this assay was highly selective for OTA over its structurally related analogues.
Keyword	G-quadruplex Iridium(Iii) Complex Label-free Luminescent Ochratoxin a
DOI	10.1021/acsami.5b01702
URL	View the original
Indexed By	SCIE
Language	英語English
WOS Research Area	Science & Technology - Other Topics ; Materials Science
WOS Subject	Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS ID	WOS:000353607100058
The Source to Article	Scopus
Scopus ID	2-s2.0-84928578746
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Corresponding Author	Leung C.-H.
Affiliation	1.Hong Kong Baptist Univ, Dept Chem, Kowloon Tong, Hong Kong, Peoples R China 2.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China 3.Hong Kong Baptist Univ, Partner State Key Lab Environm & Biol Anal, Hong Kong, Hong Kong, Peoples R China
Corresponding Author Affilication	University of Macau
Recommended Citation GB/T 7714	Lu L.,Wang M.,Liu L.-J.,et al. Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex[J]. ACS Applied Materials and Interfaces, 2015, 7(15), 8313.
APA	Lu L.., Wang M.., Liu L.-J.., Leung C.-H.., & Ma D.-L. (2015). Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex. ACS Applied Materials and Interfaces, 7(15), 8313.
MLA	Lu L.,et al."Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex".ACS Applied Materials and Interfaces 7.15(2015):8313.

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