English | 繁體
UM  > Faculty of Health Sciences
Residential Collegefalse
Status已發表Published
Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging
Wu, Yayun1,2; Chen, Zhizhen3; Zhang, Pengfei1,4; Zhou, Lihua1; Jiang, Tao1; Chen, Huajie5,6; Gong, Ping1; Dimitrov, Dimiter S.7; Cai, Lintao1; Zhao, Qi3
2018-07-07
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume54Issue:53Pages:7314-7317
Abstract

We developed highly bright and stable far-red emissive AIEdots by using a new kind of click-functional PEG grafted amphiphilic polymer to coat hydrophobic AIE-active polymers (PDFDP). Furthermore, an anti-HER2 recombinant fully human antibody was produced and conjugated on the AIEdots via metal-free click chemistry to fabricate in vivo tumor-targeting nanoprobes.

DOI10.1039/c8cc03037e
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000436566700009
PublisherROYAL SOC CHEMISTRY
The Source to ArticleWOS
Scopus ID2-s2.0-85049345400
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorZhao, Qi
Affiliation1.Chinese Acad Sci, Shenzhen Engn Lab Nanomed & Nanoformulat, CAS Key Lab Hlth Informat,Guangdong Key Lab Nanom, Shenzhen Inst Adv Technol,Inst Biomed & Biotechno, Shenzhen 518055, Peoples R China
2.Chinese Acad Sci, Inst Chem, CAS Research Educ Ctr Excellence Mol Sci, Key Lab Mol Nanostruct & Nanotechnol, Beijing 100190, Peoples R China
3.Univ Macau, Fac Hlth Sci, Taipa, Macau, Peoples R China
4.Hong Kong Univ Sci & Technol, Dept Chem & Biol Engn, Kowloon, Hong Kong, Peoples R China
5.Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Adv Funct Polymer Mat,Coll Hunan Prov, Xiangtan 411105, Peoples R China
6.Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environmentally Friendly Chem & Applicat, Xiangtan 411105, Peoples R China
7.Univ Pittsburgh, Med Sch, Ctr Antibody Therapeut, Pittsburgh, PA USA
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714		 Wu, Yayun,Chen, Zhizhen,Zhang, Pengfei,et al. Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging[J]. CHEMICAL COMMUNICATIONS, 2018, 54(53), 7314-7317.
APA Wu, Yayun., Chen, Zhizhen., Zhang, Pengfei., Zhou, Lihua., Jiang, Tao., Chen, Huajie., Gong, Ping., Dimitrov, Dimiter S.., Cai, Lintao., & Zhao, Qi (2018). Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging. CHEMICAL COMMUNICATIONS, 54(53), 7314-7317.
MLA Wu, Yayun,et al."Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging".CHEMICAL COMMUNICATIONS 54.53(2018):7314-7317.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wu, Yayun]'s Articles
[Chen, Zhizhen]'s Articles
[Zhang, Pengfei]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wu, Yayun]'s Articles
[Chen, Zhizhen]'s Articles
[Zhang, Pengfei]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wu, Yayun]'s Articles
[Chen, Zhizhen]'s Articles
[Zhang, Pengfei]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.