| Residential College | false |
| Status | 已發表Published |
| Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing | |
Chen, Zhe1,2 ; Ding, Zhaoyang1; Zhang, Guangya3; Tian, Leilei2; Zhang, Xuanjun1
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| 2018-07 | |
| Source Publication | MOLECULES
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| ISSN | 1420-3049 |
| Volume | 23Issue:7 |
| Abstract | In this work, an aggregation-induced emission (AIE) molecule (tetraphenylethene derivative, TPE-COOH) was conjugated to elastin-like polypeptides (ELPs40) via an amide bond to form ELPs40-TPE. The successful synthesis of ELPs40-TPE was confirmed by Circular Dichroism spectroscopy, gel electrophoresis, UV-vis absorption, and fluorescence emission spectroscopy. ELPs40-TPE possessed both amphiphilicity and the features of an AIE, and the fluorescence intensity was dependent on the local temperature. The Hela cells imaging indicated that ELPs40-TPE has great potential for bio-imaging applications because of its advantages of high fluorescence intensity, good water-solubility, and remarkable biocompatibility. |
| Keyword | Elastin-like Polypeptides (Elps) Aggregation-induced-emission (Aie) Thermo-responsive Temperature Sensing |
| DOI | 10.3390/molecules23071725 |
| URL | View the original |
| Indexed By | SCIE |
| Language | 英語English |
| WOS Research Area | Biochemistry & Molecular Biology ; Chemistry |
| WOS Subject | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| WOS ID | WOS:000445301800228 |
| Publisher | MDPI |
| The Source to Article | WOS |
| Scopus ID | 2-s2.0-85051760104 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | Faculty of Health Sciences |
| Affiliation | 1.Univ Macau, Fac Hlth Sci, Taipa 999078, Macao, Peoples R China 2.Southern Univ Sci & Technol, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China 3.Huaqiao Univ, Dept Biotechnol & Bioengn, Xiamen 361021, Peoples R China |
| First Author Affilication | University of Macau |
| Recommended Citation GB/T 7714 | Chen, Zhe,Ding, Zhaoyang,Zhang, Guangya,et al. Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing[J]. MOLECULES, 2018, 23(7). |
| APA | Chen, Zhe., Ding, Zhaoyang., Zhang, Guangya., Tian, Leilei., & Zhang, Xuanjun (2018). Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing. MOLECULES, 23(7). |
| MLA | Chen, Zhe,et al."Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing".MOLECULES 23.7(2018). |
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