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Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit [n] uril (n = 7, 8)
Hang Yin2; Qiaoxian Huang2; Wenwen Zhao2; David Bardelang1; Didier Siri1; Xiuping Chen2; Simon M. Y. Lee2; Ruibing Wang2
2018-04-20
Source PublicationJournal of Organic Chemistry
ISSN0022-3263
Volume83Issue:8Pages:4882-4887
Abstract

This is the first time that cucurbit[7]uril and cucurbit[8]uril have been demonstrated to serve as synthetic receptors for a halonium guest species, diphenyleneiodonium, modulating its bioactivities and alleviating its cardiotoxicity, which further expands the onium family of guest molecules for the cucurbit[n]uril family and provides new insights for halonium-cucurbit[n]uril host-guest chemistry and its potential applications in pharmaceutical chemistry.

DOI10.1021/acs.joc.8b00543
URLView the original
Indexed BySCIE
WOS Research AreaChemistry
WOS SubjectChemistry, Organic
WOS IDWOS:000430898500058
Scopus ID2-s2.0-85045727410
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Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF PHARMACEUTICAL SCIENCES
Institute of Chinese Medical Sciences
THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU)
Corresponding AuthorRuibing Wang
Affiliation1.Institut de Chimie Radicalaire
2.University of Macau
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Hang Yin,Qiaoxian Huang,Wenwen Zhao,et al. Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit [n] uril (n = 7, 8)[J]. Journal of Organic Chemistry, 2018, 83(8), 4882-4887.
APA Hang Yin., Qiaoxian Huang., Wenwen Zhao., David Bardelang., Didier Siri., Xiuping Chen., Simon M. Y. Lee., & Ruibing Wang (2018). Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit [n] uril (n = 7, 8). Journal of Organic Chemistry, 83(8), 4882-4887.
MLA Hang Yin,et al."Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit [n] uril (n = 7, 8)".Journal of Organic Chemistry 83.8(2018):4882-4887.
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