Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment

doi:10.1016/j.snb.2017.11.047

UM > Institute of Chinese Medical Sciences

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	Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment
	Lu L.2; Liu C.1; Li G.3 ; Liu L.-J.3 ; Leung C.-H.3 ; Ma D.-L.1
	2018-03-01
Source Publication	Sensors and Actuators, B: Chemical
ISSN	09254005
Volume	257 Pages:860-865
Abstract	A novel graphene oxide (GO)-based pH sensor was designed and prepared through covalently attaching a zwitterionic betaine molecule onto a GO surface. This betaine-modified GO (BMGO) exhibited high water solubility and low toxicity. In aqueous media, BMGO displayed increased fluorescence in acidic conditions and decreased fluorescence in basic conditions. BMGO possesses a pH sensing range from 4 to 12 with excellent reversibility, quick response and high stability. With its high sensitivity and robustness, BMGO can be used to monitor the pH of intracellular contents, as demonstrated through cell imaging.
Keyword	Betaine Fluorescent Graphene Oxide Ph Sensor
DOI	10.1016/j.snb.2017.11.047
URL	View the original
Language	英語English
WOS ID	WOS:000418868700098
Scopus ID	2-s2.0-85034065934
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Affiliation	1.Hong Kong Baptist University 2.Qingdao Agricultural University 3.University of Macau
Recommended Citation GB/T 7714	Lu L.,Liu C.,Li G.,et al. Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment[J]. Sensors and Actuators, B: Chemical, 2018, 257, 860-865.
APA	Lu L.., Liu C.., Li G.., Liu L.-J.., Leung C.-H.., & Ma D.-L. (2018). Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment. Sensors and Actuators, B: Chemical, 257, 860-865.
MLA	Lu L.,et al."Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment".Sensors and Actuators, B: Chemical 257(2018):860-865.

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