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Alcohol, stem cells and cancer
Shoujun Gu1; Bao-Ngoc Nguyen1; Shuyun Rao1; Shulin Li2; Kirti Shetty3; Asif Rashid4; Vivek Shukla5; Chu-Xia Deng1,6; Lopa Mishra1,7; Bibhuti Mishra1
2017-09
Source PublicationGenes & Cancer
ISSN1947-6019
Volume8Issue:9-10Pages:695-700
Abstract

Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

KeywordAlcohol Cancer Stem Cells Tgf-β Dna Repair
DOI10.18632/genesandcancer.156
Language英語English
Scopus ID2-s2.0-85042867790
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Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorChu-Xia Deng; Lopa Mishra; Bibhuti Mishra
Affiliation1.Department of Surgery, Center for Translational Medicine, George Washington University, Washington, DC, USA
2.Departments of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
3.Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
4.Departments of Gastroenterology and Liver Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
5.Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA
6.Faculty of Health Sciences, University of Macau, Macau SAR, China
7.Surgical Service, Veterans Affairs Medical Center, Washington DC, USA
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Shoujun Gu,Bao-Ngoc Nguyen,Shuyun Rao,et al. Alcohol, stem cells and cancer[J]. Genes & Cancer, 2017, 8(9-10), 695-700.
APA Shoujun Gu., Bao-Ngoc Nguyen., Shuyun Rao., Shulin Li., Kirti Shetty., Asif Rashid., Vivek Shukla., Chu-Xia Deng., Lopa Mishra., & Bibhuti Mishra (2017). Alcohol, stem cells and cancer. Genes & Cancer, 8(9-10), 695-700.
MLA Shoujun Gu,et al."Alcohol, stem cells and cancer".Genes & Cancer 8.9-10(2017):695-700.
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