Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern

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	Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern
	Chee K.Y.3; Tripathi A.11; Avasthi A.17; Chong M.Y.5; Xiang Y.T.20 ; Sim K.13; Kanba S.14; He Y.L.16; Lee M.S.6; Chiu H.F.K.10; Yang S.Y.4; Kuga H.14; Udomratn P.19; Tanra A.J.18; Maramis M.M.9; Grover S.17; Mahendran R.15; Kallivayalil R.A.1; Shen W.W.12; Shinfuku N.8; Tan C.H.7; Sartorius N.2
	2016-03-01
Source Publication	East Asian Archives of Psychiatry
ISSN	22247041 20789947
Volume	26 Issue:1 Pages:10-17
Abstract	Objective: Pharmacotherapy of depression in children and adolescents is complex. In the absence of research into the efficacy and safety of antidepressants in this group of patients, their off-label prescription is common. This paper aimed to illustrate the prescription pattern of antidepressants in children and adolescents from major psychiatric centres in Asia. Methods: The Research on Asia Psychotropic Prescription Pattern on Antidepressants worked collaboratively in 2013 to study the prescription pattern of antidepressants in Asia using a unified research protocol and questionnaire. Forty psychiatric centres from 10 Asian countries / regions participated and 2321 antidepressant prescriptions were analysed. Results: A total of 4.7% antidepressant prescriptions were for children and adolescents. Fluoxetine, sertraline, and escitalopram were the most common antidepressants prescribed for children and adolescents. Almost one-third (30.3%) of prescriptions were for diagnoses other than depressive and anxiety disorders. There was less antidepressant polypharmacy and concomitant use of benzodiazepine, but more concomitant use of antipsychotics in children and adolescents compared with adults. Conclusion: Off-label use of antidepressants in children and adolescents was reported by 40 Asian psychiatric institutions that participated in the study. In-service education and regulatory mechanisms should be reinforced to ensure efficacy and safety of antidepressants in children and adolescents.
Keyword	Adolescent Antidepressive agents Child Ethnopsychology
URL	View the original
Language	英語English
Fulltext Access	View Full-Text via Scopus
Document Type	Journal article
Collection	Faculty of Health Sciences
Affiliation	1.Pushpagiri Medical College 2.Association for the Improvement of Mental Health Programmes 3.Kuala Lumpur Hospital 4.Taipei City Hospital Taiwan 5.Chang Gung Memorial Hospital 6.Korea University 7.National University of Singapore 8.Kobe University 9.Universitas Airlangga 10.Chinese University of Hong Kong 11.Chhatrapati Shahuji Maharaj Medical University 12.Taipei Medical University 13.Singapore Institute of Mental Health 14.Kyushu University 15.National University Hospital, Singapore 16.Shanghai Mental Health Center 17.Postgraduate Institute of Medical Education and Research 18.Hasanuddin University 19.Prince of Songkla University 20.Universidade de Macau
Recommended Citation GB/T 7714	Chee K.Y.,Tripathi A.,Avasthi A.,et al. Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern[J]. East Asian Archives of Psychiatry, 2016, 26(1), 10-17.
APA	Chee K.Y.., Tripathi A.., Avasthi A.., Chong M.Y.., Xiang Y.T.., Sim K.., Kanba S.., He Y.L.., Lee M.S.., Chiu H.F.K.., Yang S.Y.., Kuga H.., Udomratn P.., Tanra A.J.., Maramis M.M.., Grover S.., Mahendran R.., Kallivayalil R.A.., Shen W.W.., ...& Sartorius N. (2016). Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern. East Asian Archives of Psychiatry, 26(1), 10-17.
MLA	Chee K.Y.,et al."Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern".East Asian Archives of Psychiatry 26.1(2016):10-17.

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