| Residential College | false |
| Status | 已發表Published |
| Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study | |
Grover S.15; Avasthi A.15; Tripathi A.10; Tanra A.J.16; Chee K.Y.3; He Y.L.14; Chiu H.F.K.9; Kuga H.12; Lee M.S.5; Chong M.Y.8; Udormatn P.17; Kanba S.12; Yang S.Y.4; Si T.M.13; Sim K.2; Tan C.H.6; Shen W.W.11; Xiang Y.T.18 ; Sartorius N.1; Shinfuku N.7
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| 2015-09-01 | |
| Source Publication | East Asian Archives of Psychiatry
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| ISSN | 22247041 20789947 |
| Volume | 25Issue:3Pages:99-107 |
| Abstract | Objective: To evaluate the prescription pattern of antidepressants in patients with medical co-morbidity from major psychiatric centres in Asia. Methods: The Research on Asian Psychotropic Prescription Pattern for Antidepressants (REAP-AD 2013) collected data from 42 psychiatric centres in 10 Asian countries and regions. Antidepressant prescriptions of 2320 patients with various psychiatric disorders were evaluated. Of these, 370 patients who had specified medical co-morbidities formed the study cohort. Results: Escitalopram (20%) and mirtazapine (20%) were the most commonly prescribed antidepressants in patients with medical co-morbidity followed by sertraline (16%), trazodone (15%), and paroxetine (12%). Overall, more than half (52%; 247/476) of prescriptions comprised selective serotonin reuptake inhibitors. Slightly less than two-thirds (63%; n = 233) of patients received at least 1 selective serotonin reuptake inhibitor. In addition, 79% of patients were prescribed only 1 antidepressant. The mean number of antidepressants used per patient was 1.25 (standard deviation, 0.56). There were subtle differences in the most preferred antidepressant across medical illnesses such as diabetes mellitus, liver dysfunction, acid peptic disease, and cerebrovascular disease. Differences were also seen in prescription patterns across different countries. Conclusion: Although selective serotonin reuptake inhibitors formed the bulk of antidepressant prescriptions in the presence of medical co-morbidity, mirtazapine was also commonly used in the presence of medical co-morbidities. Specified medical morbidities do influence the selection of antidepressants. |
| Keyword | Antidepressive agents Asia Comorbidity |
| URL | View the original |
| Language | 英語English |
| Fulltext Access | |
| Document Type | Journal article |
| Collection | Faculty of Health Sciences |
| Affiliation | 1.Association for the Improvement of Mental Health Programmes 2.Institute of Public Health 3.Kuala Lumpur Hospital 4.Taipei City Hospital Taiwan 5.Korea University 6.National University of Singapore 7.Kobe University 8.Chang Gung University 9.Chinese University of Hong Kong 10.Chhatrapati Shahuji Maharaj Medical University 11.Taipei Medical University 12.Kyushu University 13.Peking University 14.Shanghai Mental Health Center 15.Postgraduate Institute of Medical Education and Research 16.Hasanuddin University 17.Prince of Songkla University 18.Universidade de Macau |
| Recommended Citation GB/T 7714 | Grover S.,Avasthi A.,Tripathi A.,et al. Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study[J]. East Asian Archives of Psychiatry, 2015, 25(3), 99-107. |
| APA | Grover S.., Avasthi A.., Tripathi A.., Tanra A.J.., Chee K.Y.., He Y.L.., Chiu H.F.K.., Kuga H.., Lee M.S.., Chong M.Y.., Udormatn P.., Kanba S.., Yang S.Y.., Si T.M.., Sim K.., Tan C.H.., Shen W.W.., Xiang Y.T.., Sartorius N.., & Shinfuku N. (2015). Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study. East Asian Archives of Psychiatry, 25(3), 99-107. |
| MLA | Grover S.,et al."Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study".East Asian Archives of Psychiatry 25.3(2015):99-107. |
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