CMOS biosensors for in vitro diagnosis – transducing mechanisms and applications

UM > Faculty of Science and Technology > DEPARTMENT OF COMPUTER AND INFORMATION SCIENCE

Residential College	false
Status	已發表Published
	CMOS biosensors for in vitro diagnosis – transducing mechanisms and applications
	Lei, K.M.; Mak, P. I.; Law, M. K.; Martins, R. P.
	2016-09-01
Source Publication	Lab on a Chip
ISSN	1473-0197
Pages	3664-3681
Abstract	Complementary metal oxide semiconductor (CMOS) technology enables low-cost and large-scale integration of transistors and physical sensing materials on tiny chips (e.g., <1 cm2), seamlessly combining the two key functions of biosensors: transducing and signal processing. Recent CMOS biosensors unified different transducing mechanisms (impedance, fluorescence, and nuclear spin) and readout electronics have demonstrated competitive sensitivity for in vitro diagnosis, such as detection of DNA (down to 10 aM), protein (down to 10 fM), or bacteria/cells (single cell). Herein, we detail the recent advances in CMOS biosensors, centering on their key principles, requisites, and applications. Together, these may contribute to the advancement of our healthcare system, which should be decentralized by broadly utilizing point-of-care diagnostic tools.
Keyword	CMOS biosensors
Language	英語English
The Source to Article	PB_Publication
PUB ID	24971
Document Type	Journal article
Collection	DEPARTMENT OF COMPUTER AND INFORMATION SCIENCE INSTITUTE OF MICROELECTRONICS
Corresponding Author	Mak, P. I.
Recommended Citation GB/T 7714	Lei, K.M.,Mak, P. I.,Law, M. K.,et al. CMOS biosensors for in vitro diagnosis – transducing mechanisms and applications[J]. Lab on a Chip, 2016, 3664-3681.
APA	Lei, K.M.., Mak, P. I.., Law, M. K.., & Martins, R. P. (2016). CMOS biosensors for in vitro diagnosis – transducing mechanisms and applications. Lab on a Chip, 3664-3681.
MLA	Lei, K.M.,et al."CMOS biosensors for in vitro diagnosis – transducing mechanisms and applications".Lab on a Chip (2016):3664-3681.

Files in This Item:
There are no files associated with this item.

If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible.
Content:
Email：	*
Affiliation No.
Verification Code:	Refresh

Any comments and suggestions are welcomed.
Title:	*
Content:
Email：	*
Verification Code:	Refresh