Novel TiO/BiOBr nanocomposites were prepared by hydrothermal approach to develop effective photocatalysts upon visible light for removal of contaminants from water. Different instruments have been used for characterization of physiochemical attributes of the photocatalysts. The results of photocatalytic reactions showed that the binary TiO/BiOBr (30%) heterostructure, in comparison with TiO and TiO/BiOBr (30%), has excellent photocatalytic ability in the elimination of Rhodamine B (RhB). Additionally, the binary TiO/BiOBr (30%) photocatalyst exhibited superior activity towards degradations of tetracycline (TC), methylene blue (MB), and malachite green (MG). The capability of the TiO/BiOBr (30%) nanocomposite in degradation of MG, RhB, MB, and TC is 25.8, 70.1, 65.8, and 11.8-folds greater than TiO and 6.9, 22.6, 11.4, and 6.5 times premier than BiOBr, and 2.0, 14.3, 1.50, and 1.80 times as much as TiO/BiOBr (30%), respectively. The superoxide anion radicals, and also holes play main role during the photodegradation reactions. Such a high performance was ascribed to the facile segregation and migration of photogenerated charge carriers and extended light absorption range to visible light. This study can provide a novel method for the facile preparation of visible-light-promoted photocatalysts using TiO to remedy wastewater.