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Scale-adaptive super-feature based MetricUNet for brain tumor segmentation
Liu, Yujian1,2,3; Du, Jie1,2,3; Vong, Chi Man4; Yue, Guanghui1,2,3; Yu, Juan5; Wang, Yuli5; Lei, Baiying1,2,3; Wang, Tianfu1,2,3
2022-03-01
Source PublicationBiomedical Signal Processing and Control
ISSN1746-8094
Volume73Pages:103442
Abstract

Accurate segmentation of brain tumors is very essential for brain tumor diagnosis and treatment plans. In general, brain tumor includes WT (whole tumor), TC (tumor core) and ET (enhance tumor), and TC and ET are much more important than WT clinically. However, TC and ET usually contain blurred boundaries, and occupy much fewer pixels than WT. Recently, MetricUNet based on voxel-metric learning is proposed, which considers voxel-level feature relationship in the image to obtain finer segmentation results. However, it may not be applicable in brain tumor segmentation. That is because the scales/sizes of brain tumor greatly vary between images and causing ineffective model training in MetricUNet. Moreover, it has heavy computation for considering voxel-level feature relationship in brain tumor segmentation. In this work, a Scale-adaptive Super-feature based MetricUNet (S2MetricUNet) is proposed and provides two advantages: i) higher accuracy on TC and ET since a novel scale-adaptive metric loss is proposed for learning of more context information about TC and ET while addressing the scale variation between images; ii) significant reduction on computation since a super voxel-level feature is proposed to represent a group of voxel-level features (of the same label) in non-edge regions. The experimental results on public dataset BraTS2019 have demonstrated that the improvement of our method is up to 3.38% on TC and 3.82% on ET in terms Dice. Moreover, the computation of our S2MetricUNet is reduced to about 1/11 of MetricUNet.

KeywordBrain Tumor Segmentation Metricunet Scale-adaptive Super Voxel-level Feature Voxel-metric Learning
DOI10.1016/j.bspc.2021.103442
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaEngineering
WOS SubjectEngineering, Biomedical
WOS IDWOS:000820474100012
Scopus ID2-s2.0-85120707938
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Citation statistics
Document TypeJournal article
CollectionDEPARTMENT OF COMPUTER AND INFORMATION SCIENCE
Co-First AuthorLiu, Yujian
Corresponding AuthorYue, Guanghui; Wang, Tianfu
Affiliation1.The Health Science Center, School of Biomedical Engineering, Shenzhen University, Shenzhen, 518060, China
2.The National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Shenzhen University, Shenzhen, 518060, China
3.The Marshall Laboratory of Biomedical Engineering, Shenzhen University, Shenzhen, 518060, China
4.Department of Computer and Information Science, University of Macau, Macau, SAR 999078, China
5.Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518060, China
Recommended Citation
GB/T 7714
Liu, Yujian,Du, Jie,Vong, Chi Man,et al. Scale-adaptive super-feature based MetricUNet for brain tumor segmentation[J]. Biomedical Signal Processing and Control, 2022, 73, 103442.
APA Liu, Yujian., Du, Jie., Vong, Chi Man., Yue, Guanghui., Yu, Juan., Wang, Yuli., Lei, Baiying., & Wang, Tianfu (2022). Scale-adaptive super-feature based MetricUNet for brain tumor segmentation. Biomedical Signal Processing and Control, 73, 103442.
MLA Liu, Yujian,et al."Scale-adaptive super-feature based MetricUNet for brain tumor segmentation".Biomedical Signal Processing and Control 73(2022):103442.
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