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PH-Responsive de-PEGylated nanoparticles based on triphenylphosphine–quercetin self-assemblies for mitochondria-targeted cancer therapy
Xing, L; Lyu, JY; Yang, Y; Cui, PF; Gu, LQ; Qiao, JB; He, YJ; Zhang, TQ; Sun, MJ; Lu, J.; Xu, XJ; Liu, Y; Jiang, HL
2017-08-11
Source PublicationChemical Communications
ISSN1359-7345
Pages8790-8793
Abstract

We have developed mitochondria-targeted self-assembled nanoparticles (NPs) based on amphiphilic triphenylphosphine–quercetin (TPP–Que) conjugates, which were further modified by poly(ethylene glycol) via a pH-responsive coordination bond to form TQ-PEG NPs. And it is revealed that the TQ-PEG NPs weremore effective therapeutic agents compared with Que in vitro and in vivo.

KeywordN/a
Language英語English
The Source to ArticlePB_Publication
Document TypeJournal article
CollectionDEPARTMENT OF HISTORY
Corresponding AuthorXu, XJ; Liu, Y; Jiang, HL
Recommended Citation
GB/T 7714
Xing, L,Lyu, JY,Yang, Y,et al. PH-Responsive de-PEGylated nanoparticles based on triphenylphosphine–quercetin self-assemblies for mitochondria-targeted cancer therapy[J]. Chemical Communications, 2017, 8790-8793.
APA Xing, L., Lyu, JY., Yang, Y., Cui, PF., Gu, LQ., Qiao, JB., He, YJ., Zhang, TQ., Sun, MJ., Lu, J.., Xu, XJ., Liu, Y., & Jiang, HL (2017). PH-Responsive de-PEGylated nanoparticles based on triphenylphosphine–quercetin self-assemblies for mitochondria-targeted cancer therapy. Chemical Communications, 8790-8793.
MLA Xing, L,et al."PH-Responsive de-PEGylated nanoparticles based on triphenylphosphine–quercetin self-assemblies for mitochondria-targeted cancer therapy".Chemical Communications (2017):8790-8793.
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