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二氫青蒿素抗腫瘤作用及其機制研究進展
Alternative TitleProgress in the anti-neoplastic effects and mechanisms of dihydroartemisinin
Lu, J.; Huang, MQ; Chen, X. P.; Wang, Y. T.
2011-04-21
Source Publication中國藥理學與毒理學雜誌
ISSN1000-3002
Pages397-401
Abstract

Dihydroartemisinin,an important artemisinin derivative,presents excellent anti-neoplastic potential. This article reviews the latest progress in the anti-cancer activity of dihydroartemisinin and the possible mechanisms including anti-proliferation,cell cycle arrest,apoptosis induction,anti-angiogenesis and anti-metastasis. Iron ( Ⅱ) or heme may be the direct target for dihydroartemisinin. The broad anti-cancer spectrum,the low toxicity to normal cells and the potential of anti-multi-drug resistant cells make it a likely new anti-cancer candidate compound.

KeywordDihydroartemisinin Antineoplastic Agents Cell Proliferation Neoangiogenesis Tumor Metastasis
Language其他語言Others
The Source to ArticlePB_Publication
Document TypeJournal article
CollectionINSTITUTE OF MICROELECTRONICS
Institute of Chinese Medical Sciences
Corresponding AuthorWang, Y. T.
Recommended Citation
GB/T 7714
Lu, J.,Huang, MQ,Chen, X. P.,等. 二氫青蒿素抗腫瘤作用及其機制研究進展[J]. 中國藥理學與毒理學雜誌, 2011, 397-401.
APA Lu, J.., Huang, MQ., Chen, X. P.., & Wang, Y. T. (2011). 二氫青蒿素抗腫瘤作用及其機制研究進展. 中國藥理學與毒理學雜誌, 397-401.
MLA Lu, J.,et al."二氫青蒿素抗腫瘤作用及其機制研究進展".中國藥理學與毒理學雜誌 (2011):397-401.
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