Asymmetric Total Synthesis of Cerorubenic Acid-III

doi:10.1021/jacs.8b12647

Residential College	false
Status	已發表Published
	Asymmetric Total Synthesis of Cerorubenic Acid-III
	Liu, Xin 1,3; Liu, Junyang 1,2; Wu, Jianlei 1; Huang, Guocheng 1; Liang, Rong 1; Chung, Lung Wa 1; Li, Chuang Chuang 1
	2019-02-20
Source Publication	Journal of the American Chemical Society
ISSN	0002-7863
Volume	141 Issue:7 Pages:2872-2877
Abstract	The first asymmetric total synthesis of the highly strained compound cerorubenic acid-III is reported. A type II intramolecular [5 + 2] cycloaddition allowed efficient and diastereoselective construction of the synthetically challenging bicyclo[4.4.1] ring system with a strained bridgehead (anti-Bredt) double bond in the final product. A unique transannular cyclization installed the vinylcyclopropane moiety with retention of the desired stereochemistry.
DOI	10.1021/jacs.8b12647
URL	View the original
Indexed By	SCIE ; IC ; CCR-E
Language	英語English
WOS Research Area	Chemistry
WOS Subject	Chemistry, Multidisciplinary
WOS ID	WOS:000459642000016
Scopus ID	2-s2.0-85061537896
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	University of Macau
Corresponding Author	Li, Chuang Chuang
Affiliation	1.Shenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology, Shenzhen, 518055, China 2.Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology (SUSTech), Shenzhen, 518055, China 3.Institute of Chinese Medical Sciences, University of Macau, Macau, Macao
First Author Affilication	Institute of Chinese Medical Sciences
Recommended Citation GB/T 7714	Liu, Xin,Liu, Junyang,Wu, Jianlei,et al. Asymmetric Total Synthesis of Cerorubenic Acid-III[J]. Journal of the American Chemical Society, 2019, 141(7), 2872-2877.
APA	Liu, Xin., Liu, Junyang., Wu, Jianlei., Huang, Guocheng., Liang, Rong., Chung, Lung Wa., & Li, Chuang Chuang (2019). Asymmetric Total Synthesis of Cerorubenic Acid-III. Journal of the American Chemical Society, 141(7), 2872-2877.
MLA	Liu, Xin,et al."Asymmetric Total Synthesis of Cerorubenic Acid-III".Journal of the American Chemical Society 141.7(2019):2872-2877.

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