| Residential College | false |
| Status | 已發表Published |
| Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α-glucosidase inhibitory activity | |
Song, Min1 ; Xiao, Tong1; Wu, Qiu Shuang2; Kwok, Hang Fai2 ; Chan, Ging1; Lin, Li Gen1; Zhang, Xiao Qi3; Ye, Wen Cai3; He, Sheng Jiang4; Zhang, Qing Wen1
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| 2021-10 | |
| Source Publication | Natural Product Research
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| ISSN | 1478-6419 |
| Volume | 36Issue:12Pages:3085-3094 |
| Abstract | Three new biflavonoids, umcephabiovins C − E (1 − 3), along with fourteen known compounds were isolated from the twigs and leaves of Cephalotaxus oliveri. Their structures and configurations were elucidated by UV, IR, NMR, ECD, and HR-ESI-MS spectra. Compounds 1 − 3 exhibited significant α-glucosidase inhibitory activity with IC values of 7.05 ± 2.66, 24.45 ± 4.73, and 1.84 ± 1.14 μM, respectively. Compound 11 showed moderate cytotoxicity against the BaF3/T315I cell line. |
| Keyword | Biflavonoids Cephalotaxus Oliveri Cytotoxicity Α-glucosidase Inhibitory Activity |
| DOI | 10.1080/14786419.2021.1958328 |
| URL | View the original |
| Language | 英語English |
| Publisher | Taylor and Francis Ltd. |
| Scopus ID | 2-s2.0-85118155959 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU) Faculty of Health Sciences Institute of Chinese Medical Sciences Institute of Translational Medicine |
| Affiliation | 1.State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China 2.Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China 3.Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China 4.Guangzhou Egg Biotechnology, Co., Ltd, Guangzhou, China |
| First Author Affilication | Institute of Chinese Medical Sciences |
| Recommended Citation GB/T 7714 | Song, Min,Xiao, Tong,Wu, Qiu Shuang,et al. Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α-glucosidase inhibitory activity[J]. Natural Product Research, 2021, 36(12), 3085-3094. |
| APA | Song, Min., Xiao, Tong., Wu, Qiu Shuang., Kwok, Hang Fai., Chan, Ging., Lin, Li Gen., Zhang, Xiao Qi., Ye, Wen Cai., He, Sheng Jiang., & Zhang, Qing Wen (2021). Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α-glucosidase inhibitory activity. Natural Product Research, 36(12), 3085-3094. |
| MLA | Song, Min,et al."Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α-glucosidase inhibitory activity".Natural Product Research 36.12(2021):3085-3094. |
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