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Advance toward isolation, extraction, metabolism and health benefits of kaempferol, a major dietary flavonoid with future perspectives
Yang, Li1; Gao, Yongchao2; Bajpai, Vivek K.3; El-Kammar, Heba A.4; Simal-Gandara, Jesus5; Cao, Hui5,6; Cheng, Ka Wing7; Wang, Mingfu7; Arroo, Randolph R.J.8; Zou, Liang9; Farag, Mohamed A.4,10; Zhao, Yonghua1; Xiao, Jianbo5,11
2023
Source PublicationCritical Reviews in Food Science and Nutrition
ISSN1040-8398
Volume63Issue:16Pages:2773-2789
Abstract

As a major ubiquitous secondary metabolite, flavonoids are widely distributed in planta. Among flavonoids, kaempferol is a typical natural flavonol in diets and medicinal plants with myriad bioactivities, such as anti-inflammatory activity, anti-cancer activity, antioxidant activity, and anti-diabetic activity. However, the natural sources, absorption and metabolism as well as the bioactivities of kaempferol have not been reviewed comprehensively and systematically. This review highlights the latest research progress and the effect of kaempferol in the prevention and treatment of various chronic diseases, as well as its protective health effects, and provides a theoretical basis for future research to be used in nutraceuticals. Further, comparison of the different extraction and analytical methods are presented to highlight the most optimum for PG recovery and its detection in plasma and body fluids. Such review aims at improving the value-added applications of this unique dietary bioactive flavonoids at commercial scale and to provide a reference for its needed further development.

KeywordKaempferol Anti-inflammation Anti-cancer Anti-diabetic Extraction Analysis Metabolism
DOI10.1080/10408398.2021.1980762
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaFood Science & Technology ; Nutrition & Dietetics
WOS SubjectFood Science & Technology ; Nutrition & Dietetics
WOS IDWOS:000701553600001
Scopus ID2-s2.0-85115355767
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Citation statistics
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorZhao, Yonghua; Xiao, Jianbo
Affiliation1.Institute of Chinese Medical Sciences, University of Macau, Macau, China
2.Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China
3.Department of Energy and Materials Engineering, Dongguk University Seoul, Seoul, South Korea
4.Pharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt
5.Department of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, University of Vigo-Ourense Campus, Ourense, Spain
6.College of Food Science and Technology, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Guangdong Provincial Engineering Technology Research Center of Seafood, Key Laboratory of Advanced Processing of Aquatic Product of Guangdong Higher Education Institution, Guangdong Ocean University, Zhanjiang, China
7.Institute for Advanced Study, Shenzhen University, Shenzhen, China
8.Leicester School of Pharmacy, De Montfort University, Leicester, United Kingdom
9.Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering and Technology Research Center of Coarse Cereal Industrialization, School of Food and Biological Engineering, Chengdu University, Chengdu, China
10.Department of Chemistry, School of Sciences and Engineering, American University in Cairo, New Cairo, Egypt
11.International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Yang, Li,Gao, Yongchao,Bajpai, Vivek K.,et al. Advance toward isolation, extraction, metabolism and health benefits of kaempferol, a major dietary flavonoid with future perspectives[J]. Critical Reviews in Food Science and Nutrition, 2023, 63(16), 2773-2789.
APA Yang, Li., Gao, Yongchao., Bajpai, Vivek K.., El-Kammar, Heba A.., Simal-Gandara, Jesus., Cao, Hui., Cheng, Ka Wing., Wang, Mingfu., Arroo, Randolph R.J.., Zou, Liang., Farag, Mohamed A.., Zhao, Yonghua., & Xiao, Jianbo (2023). Advance toward isolation, extraction, metabolism and health benefits of kaempferol, a major dietary flavonoid with future perspectives. Critical Reviews in Food Science and Nutrition, 63(16), 2773-2789.
MLA Yang, Li,et al."Advance toward isolation, extraction, metabolism and health benefits of kaempferol, a major dietary flavonoid with future perspectives".Critical Reviews in Food Science and Nutrition 63.16(2023):2773-2789.
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