| Residential College | false |
| Status | 已發表Published |
| Venom Peptide – A Prospective Spearhead in Cancer Treatment | |
Wong, J.P.C.; Li, B. ; Kwok, H. F.
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| 2017-06-21 | |
| Source Publication | Combinatorial Chemistry & High Throughput Screening
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| ISSN | 1875-5402 |
| Pages | 357-375 |
| Abstract | Cancer is a condition of genetically or environmentally mutated, uncontrollable cell growth that directly affects human morbidity and mortality. Many treatments have been adopted to reduce cancer cell proliferation; however, new mutated developments of some cancer cells have started to show resistance towards current therapies and treatments that cause some drugs to lose their efficacy. Additionally, deleterious side-effects of some hard application methods like radiation therapy, chemotherapy, and surgery are less favorable. Increasing research effort has revealed that peptides and toxins identified from underutilized natural resources including venomous reptiles, amphibians, insects, arachnids, marine organisms and plants are being employed in cancer treatment. Continuous effort has stimulated interest to discover and develop more new potential anticancer compounds from these sources. This review highlights some of the selected peptides and toxins from various sources in combating malignant cells, the selectivity towards specific anticancer mechanisms, and the prospective of conjugated peptide as a single entity for a new therapeutic strategy. |
| Keyword | Cancer Venom Reptiles Amphibians Insects Plants Peptide toxin Mechanisms |
| URL | View the original |
| Language | 英語English |
| The Source to Article | PB_Publication |
| PUB ID | 19988 |
| Document Type | Journal article |
| Collection | DEPARTMENT OF BIOMEDICAL SCIENCES |
| Corresponding Author | Kwok, H. F. |
| Recommended Citation GB/T 7714 | Wong, J.P.C.,Li, B.,Kwok, H. F.. Venom Peptide – A Prospective Spearhead in Cancer Treatment[J]. Combinatorial Chemistry & High Throughput Screening, 2017, 357-375. |
| APA | Wong, J.P.C.., Li, B.., & Kwok, H. F. (2017). Venom Peptide – A Prospective Spearhead in Cancer Treatment. Combinatorial Chemistry & High Throughput Screening, 357-375. |
| MLA | Wong, J.P.C.,et al."Venom Peptide – A Prospective Spearhead in Cancer Treatment".Combinatorial Chemistry & High Throughput Screening (2017):357-375. |
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