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Investigating the Dynamic Binding Behavior of PMX53 Cooperating with Allosteric Antagonist NDT9513727 to C5a Anaphylatoxin Chemotactic Receptor 1 through Gaussian Accelerated Molecular Dynamics and Free-Energy Perturbation Simulations Journal article
Xiaoli, An, Yuzhen, Niu, Qiong, Yang, Yang, Lei, Yao, Xiaojun, Bing, Zhitong. Investigating the Dynamic Binding Behavior of PMX53 Cooperating with Allosteric Antagonist NDT9513727 to C5a Anaphylatoxin Chemotactic Receptor 1 through Gaussian Accelerated Molecular Dynamics and Free-Energy Perturbation Simulations[J]. ACS Chemical Neuroscience, 2022, 13(23), 3502-3511.
Authors:  Xiaoli, An;  Yuzhen, Niu;  Qiong, Yang;  Yang, Lei;  Yao, Xiaojun; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.1/4.3 | Submit date：2023/01/30
C5ar1  Free-energy Perturbation (Fep)  Gaussian Accelerated Molecular Dynamics (Gamd) Simulation  Ndt9513727  Pmx53  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
Ju,Yaojun, Chakravarty,Harapriya, Tam,Kin Yip. An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease[J]. ACS Chemical Neuroscience, 2020, 11(20), 3346-3357.
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:4.1/4.3 | Submit date：2021/03/04
Alzheimer's Disease  Amyloid Beta  Cholinesterase  Dual Inhibition  
A novel isoquinolinium dual inhibitor of cholinesterases and amyloid beta aggregation mitigates neuropathological changes in a triple-transgenic mouse model of Alzheimer’s disease Journal article
Ju, Y., Chakravarty, H., Tam, K. Y.. A novel isoquinolinium dual inhibitor of cholinesterases and amyloid beta aggregation mitigates neuropathological changes in a triple-transgenic mouse model of Alzheimer’s disease[J]. ACS Chemical Neuroscience, 2020, 3346-3357.
Authors:  Ju, Y.;  Chakravarty, H.;  Tam, K. Y.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:4.1/4.3 | Submit date：2022/07/27
Cholinesterase  Amyloid Beta  Dual Inhibition  Alzheimer’s Disease  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
Chuwen Li, Yaqi Bian, Yu Feng, Fan Tang, Liang Wang, Maggie Pui Man Hoi, Dan Ma, Chao Zhao, Simon Ming Yuen Lee. Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization[J]. ACS CHEMICAL NEUROSCIENCE, 2019, 10(5), 2434-2449.
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang; et al.
Favorite | TC[WOS]:24 TC[Scopus]:26  IF:4.1/4.3 | Submit date：2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells Journal article
You, Tingting, Cheng, Yufang, Zhong, Jiahong, Bi, Bingtian, Zeng, Bingqing, Zheng, Wenhua, Wang, Haitao, Xu, Jiangping. Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells[J]. ACS CHEMICAL NEUROSCIENCE, 2017, 8(11), 2381-2392.
Authors:  You, Tingting;  Cheng, Yufang;  Zhong, Jiahong;  Bi, Bingtian;  Zeng, Bingqing; et al.
Favorite | TC[WOS]:34 TC[Scopus]:37  IF:4.1/4.3 | Submit date：2018/10/30
Phosphodiesterase 4  Roflupram  Autophagy  Inflammasome  Microglia  Neuroinflammation  
Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage Journal article
Yan F., Wang H., Gao Y., Xu J., Zheng W.. Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage[J]. ACS Chemical Neuroscience, 2017, 8(8), 1713-1723.
Authors:  Yan F.;  Wang H.;  Gao Y.;  Xu J.;  Zheng W.
Favorite | TC[WOS]:32 TC[Scopus]:37 | Submit date：2018/12/21
Amd  Artemisin  Erk1/2  H2o2  P38  Ros  
Artemisinin DamageProtects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Journal article
Yan, Fengxia, Wang, Haitao, Gao, Yang, Xu, Jiangping, Zheng, Wenhua. Artemisinin DamageProtects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed[J]. ACS CHEMICAL NEUROSCIENCE, 2017, 8(8), 1713-1723.
Authors:  Yan, Fengxia;  Wang, Haitao;  Gao, Yang;  Xu, Jiangping;  Zheng, Wenhua
Favorite | TC[WOS]:32 TC[Scopus]:37  IF:4.1/4.3 | Submit date：2018/10/30
Amd  Artemisin  H2o2  Ros  P38  Erk1/2  
Roflupram, a Phosphodiesterase Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells Journal article
Zheng, W.. Roflupram, a Phosphodiesterase Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells[J]. ACS chemical neuroscience, 2017, 1-11.
Authors:  Zheng, W.
Favorite |   IF:4.1/4.3 | Submit date：2022/08/31
Phosphodiesterase 4  roflupram  autophagy  inflammasome  microglia  neuroinflammation  
Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer’s Disease Journal article
Wu X., Kosaraju J., Zhou W., Tam K.Y.. Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer’s Disease[J]. ACS Chemical Neuroscience, 2017, 8(3), 676-685.
Authors:  Wu X.;  Kosaraju J.;  Zhou W.;  Tam K.Y.
Favorite | TC[WOS]:22 TC[Scopus]:23 | Submit date：2018/12/18
3xtg-ad  Aggregation  Alzheimer’s Disease  Amyloid β  Neuroprotection  Sh-sy5y  Slm  
Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease Journal article
Wu, Xiaoli, Kosaraju, Jayasankar, Zhou, Wei, Tam, Kin Yip. Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease[J]. ACS CHEMICAL NEUROSCIENCE, 2017, 8(3), 676-685.
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite | TC[WOS]:22 TC[Scopus]:23  IF:4.1/4.3 | Submit date：2018/10/30
Amyloid Beta  Aggregation  Alzheimer's Disease  Slm  3xtg-ad  Neuroprotection  Sh-sy5y