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Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches Journal article
Wang, Wei, Deng, Shiwei, Lin, Jinzhong, Ouyang, Defang. Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches[J]. Acta Pharmaceutica Sinica B, 2024, 14(10), 4591-4607.
Authors:  Wang, Wei;  Deng, Shiwei;  Lin, Jinzhong;  Ouyang, Defang
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:14.7/14.1 | Submit date：2024/09/03
Lipid Nanoparticle  Rna  Ionizable Lipid  In Vivo Transportation  Endosomal Escape  Metabolism  Quantum Mechanics  Physiologically-based Pharmacokinetics  
Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB Journal article
Linghu, Kegang, Cui, Wenqing, Li, Taiqin, Tuo, Yueting, Wang, Dasong, Pan, Huiqi, Zhang, Tian, Lin, Ligen, Yu, Hua, Hu, Xiaoxia, Li, Haiyang, Shen, Xiangchun. Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB[J]. Acta Pharmaceutica Sinica B, 2024, 14(8), 3561-3575.
Authors:  Linghu, Kegang;  Cui, Wenqing;  Li, Taiqin;  Tuo, Yueting;  Wang, Dasong; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:14.7/14.1 | Submit date：2024/05/16
A-methylene-g-  Butyrolactone  Rheumatoid Arthritis  Nf-kb P65  Synovial  Microenvironment  Sesquiterpene Lactones  
YOD1 regulates microglial homeostasis by deubiquitinating MYH9 to promote the pathogenesis of Alzheimer's disease Journal article
Jinfeng Sun, Fan Chen, Lingyu She, Yuqing Zeng, Hao Tang, Bozhi Ye, ZHENG WENHUA, Li Xiong, Liwei Li, Luyao Li, Qin Yu, Linjie Chen, Wei Wang, Guang Liang, Xia Zhao. YOD1 regulates microglial homeostasis by deubiquitinating MYH9 to promote the pathogenesis of Alzheimer's disease[J]. Acta Pharmaceutica Sinica B, 2024.
Authors:  Jinfeng Sun;  Fan Chen;  Lingyu She;  Yuqing Zeng;  Hao Tang; et al.
Favorite |   IF:14.7/14.1 | Submit date：2024/08/31
ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction Journal article
Xu, Shiqiang, Ma, Qilian, Shen, Junwen, Li, Ningning, Sun, Shan, Wang, Nana, Chen, Yang, Dong, Chunsheng, Tam, Kin Yip, Prehn, Jochen H.M., Wang, Hongfeng, Ying, Zheng. ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction[J]. Acta Pharmaceutica Sinica B, 2024, 14(5), 2026-2038.
Authors:  Xu, Shiqiang;  Ma, Qilian;  Shen, Junwen;  Li, Ningning;  Sun, Shan; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:14.7/14.1 | Submit date：2024/05/16
Amyotrophic Lateral Sclerosis  Autophagy  Bcl2  Becn1/beclin 1  C9orf72  Dipeptide Repeat  Frontotemporal Dementia  Neurodegeneration  
Triple three-dimensional MS/MS spectrum facilitates quantitative ginsenosides-targeted sub-metabolome characterization in notoginseng Journal article
Zhang, Ke, Jia, Jinru, Li, Ting, Liu, Wenjing, Tu, Pengfei, Wan, Jian Bo, Li, Jun, Song, Yuelin. Triple three-dimensional MS/MS spectrum facilitates quantitative ginsenosides-targeted sub-metabolome characterization in notoginseng[J]. Acta Pharmaceutica Sinica B, 2024.
Authors:  Zhang, Ke;  Jia, Jinru;  Li, Ting;  Liu, Wenjing;  Tu, Pengfei; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:14.7/14.1 | Submit date：2024/06/05
Full Exciting Energy Ramp-ms3 Spectrum  Ginsenosides  Notoginseng  Quantitative Sub-metabolome Characterization  Structural Identification  
Heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke Journal article
Li, Ru, Wei, Riqing, Liu, Chenxin, Zhang, Keying, He, Sixiao, Liu, Zhifeng, Huang, Junhao, Tang, Youyong, An, Qiyuan, Lin, Ligen, Gan, Lishe, Zhao, Liying, Zou, Xiaoming, Wang, Fudi, Ping, Yuan, Ma, Qiang. Heme oxygenase 1-mediated ferroptosis in Kupffer cells initiates liver injury during heat stroke[J]. Acta Pharmaceutica Sinica B, 2024.
Authors:  Li, Ru;  Wei, Riqing;  Liu, Chenxin;  Zhang, Keying;  He, Sixiao; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:14.7/14.1 | Submit date：2024/07/04
Early Growth Response Factor 1  Ferroptosis  Heat Stroke  Heme Oxygenase 1  Kupffer Cells  Liver Injury  Nlrp3  Phosphatidylinositol 4-kinase Beta  
Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy Journal article
Fan, Yu, Feng, Ruibing, Zhang, Xinya, Wang, Zhen Liang, Xiong, Feng, Zhang, Shuihua, Zhong, Zhang Feng, Yu, Hua, Zhang, Qing Wen, Zhang, Zhang, Wang, Yitao, Li, Guodong. Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy[J]. Acta Pharmaceutica Sinica B, 2024.
Authors:  Fan, Yu;  Feng, Ruibing;  Zhang, Xinya;  Wang, Zhen Liang;  Xiong, Feng; et al.
Favorite | TC[WOS]:4 TC[Scopus]:6  IF:14.7/14.1 | Submit date：2024/05/16
Clinical Drugs  Dna-encoded Chemical Libraries  Phage Display  
GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progresses of gastric cancer Journal article
Jiang, Qiwei, Li, Yong, Cai, Songwang, Shi, Xingyuan, Yang, Yang, Xing, Zihao, He, Zhenjie, Wang, Shengte, Su, Yubin, Chen, Meiwan, Chen, Zhesheng, Shi, Zhi. GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progresses of gastric cancer[J]. Acta Pharmaceutica Sinica B, 2023, 14(2), 698-711.
Authors:  Jiang, Qiwei;  Li, Yong;  Cai, Songwang;  Shi, Xingyuan;  Yang, Yang; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:14.7/14.1 | Submit date：2024/02/22
Enzyme  Gastric Cancer  Glul  N-cadherin  Protein Stability  Protein-protein Interaction  Ubiquitination  Β-catenin  
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice Other
2023-08-01
Authors:  Fan XiaoQing;  Mai Chutian;  Zuo Ling;  Huang, Jumin;  Xie Chun; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/09/04
Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils Journal article
Peng Hua, Ruifeng Liang, Yanbei Tu, Yuying Yin, Man-Kay Law, Meiwan Chen. Reactive oxygen species and nitric oxide scavenging nanoparticles alleviating rheumatoid arthritis through adjusting the seeds and growing soils[J]. Acta Pharmaceutica Sinica B, 2023, 13(12), 5016-5029.
Authors:  Peng Hua;  Ruifeng Liang;  Yanbei Tu;  Yuying Yin;  Man-Kay Law; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:14.7/14.1 | Submit date：2023/08/21
Anti-inflammatory  Bilirubin  Cartilage Protection  Jak-stat Pathway  Notopterol  O-phenylenediamine  Rheumatoid Arthritis  Ros And No Scavenging