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Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1 Journal article
Peng-xi Deng, Marta Silva, Na Yang, Qing Wang, Xin Meng, Ke-qiang Ye, Hong-chang Gao, ZHENG WENHUA. Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1[J]. Acta Pharmacologica Sinica, 2024.
Authors:  Peng-xi Deng;  Marta Silva;  Na Yang;  Qing Wang;  Xin Meng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.9/7.6 | Submit date：2024/08/31
Alzheimer's Disease  Artemisinin  Ferroptosis  Keap1  Nrf2  Hippocampus  
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1 Journal article
Duan, Chunyan, Li, Yue, Zhi, Haoyu, Tian, Yao, Huang, Zhengyun, Chen, Suping, Zhang, Yang, Liu, Qing, Zhou, Liang, Jiang, Xiaogang, Ullah, Kifayat, Guo, Qing, Liu, Zhaohui, Xu, Ying, Han, Junhai, Hou, Jiajie, O’Connor, Darran P., Xu, Guo qiang. E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1[J]. ACTA PHARMACOLOGICA SINICA, 2024, 45, 1793-1808.
Authors:  Duan, Chunyan;  Li, Yue;  Zhi, Haoyu;  Tian, Yao;  Huang, Zhengyun; et al.
Favorite | TC[WOS]:2 TC[Scopus]:1  IF:6.9/7.6 | Submit date：2024/06/05
Bmal1  Circadian Rhythm  Proteomics  Transcriptional Activity  Ubiquitination  Ubr5  
Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma Journal article
Zhang, Qi Yi, Ding, Wen, Mo, Jian Shan, Ou-yang, Shu Min, Lin, Zi You, Peng, Ke Ren, Liu, Guo Pin, Lu, Jin Jian, Yue, Pei Bin, Lei, Jin Ping, Wang, Yan Dong, Zhang, Xiao Lei. Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma[J]. ACTA PHARMACOLOGICA SINICA, 2024.
Authors:  Zhang, Qi Yi;  Ding, Wen;  Mo, Jian Shan;  Ou-yang, Shu Min;  Lin, Zi You; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:6.9/7.6 | Submit date：2024/05/16
Acquired Sorafenib-resistance  Antisense Oligonucleotide  Hepatocellular Carcinoma  Stat3  
Paraptosis: a non-classical paradigm of cell death for cancer therapy Journal article
Xu, Chun cao, Lin, Yi fan, Huang, Mu yang, Zhang, Xiao lei, Wang, Pei, Huang, Ming qing, Lu, Jin jian. Paraptosis: a non-classical paradigm of cell death for cancer therapy[J]. Acta Pharmacologica Sinica, 2024, 45(2), 223-237.
Authors:  Xu, Chun cao;  Lin, Yi fan;  Huang, Mu yang;  Zhang, Xiao lei;  Wang, Pei; et al.
Favorite | TC[WOS]:20 TC[Scopus]:17  IF:6.9/7.6 | Submit date：2024/05/16
cancer therapy  endoplasmic reticulum  ER stress  mitochondria  paraptosis  
Paraptosis: a non-classical paradigm of cell death for cancer therapy Review article
2024
Authors:  Xu, Chun cao;  Lin, Yi fan;  Huang, Mu yang;  Zhang, Xiao lei;  Wang, Pei; et al.
Favorite | TC[WOS]:20 TC[Scopus]:17  IF:6.9/7.6 | Submit date：2024/02/22
Cancer Therapy  Endoplasmic Reticulum  Er Stress  Mitochondria  Paraptosis  
Correction to: E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1 (Acta Pharmacologica Sinica, (2024), 10.1038/s41401-024-01290-z) Other
2024-01-01
Authors:  Duan, Chun Yan;  Li, Yue;  Zhi, Hao Yu;  Tian, Yao;  Huang, Zheng Yun; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2024/07/04
Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β Journal article
Shao-Ru Chen, Zheng-Qing Li, Jun Xu, Mo-Yu Ding, Yaming Shan, Yung-Chi Cheng, Gao-Xiao Zhang, Ye-Wei Sun, Yuqiang Wang, Wang Y(王穎). Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β[J]. ACTA PHARMACOLOGICA SINICA, 2023, 44, 1637-1648.
Authors:  Shao-Ru Chen;  Zheng-Qing Li;  Jun Xu;  Mo-Yu Ding;  Yaming Shan; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.9/7.6 | Submit date：2023/07/06
Celastrol  Heat Shock Protein 90β  Hepatitis c Virus  Inflammatory Response  Rna-dependent Rna Polymerase  
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Zhu, Zhou, Liu, Liang feng, Su, Cheng fu, Liu, Jia, Tong, Benjamin Chun Kit, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Guan, Xin jie, Kan, Yu xuan, Xie, Wen jian, Zhao, Chen liang, Cheung, King ho, Lu, Jia hong, Tan, Jie qiong, Zhang, Hong jie, Song, Ju xian, Li, Min. Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy[J]. Acta Pharmacologica Sinica, 2022, 43(10), 2511-2526.
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit; et al.
Favorite | TC[WOS]:25 TC[Scopus]:21  IF:6.9/7.6 | Submit date：2022/05/17
Autophagy  Corynoxine b  Dopaminergic Neuron  
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling Journal article
Jia-li Chen, Zhe-ling Feng, Fei Zhou, Ruo-han Lou, Cheng Peng, Yang Ye, Li-gen Lin. 14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling[J]. Acta Pharmacologica Sinica, 2022, 44, 434–445.
Authors:  Jia-li Chen;  Zhe-ling Feng;  Fei Zhou;  Ruo-han Lou;  Cheng Peng; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:6.9/7.6 | Submit date：2023/01/30
14-deoxygarcinol  Adipose Tissue Inflammation  Insulin Resistance  Interleukin-1β  Nlrp3 Inflammasome  Sirtuin 2  
Novel treatment for refractory rheumatoid arthritis with total glucosides of paeony and nobiletin codelivered in a self-nanoemulsifying drug delivery system Journal article
Qu, Biao, Wang, Xiao lin, Zheng, De chong, Mai, Chu tian, Liu, Zhong qiu, Zhou, Hua, Xie, Ying. Novel treatment for refractory rheumatoid arthritis with total glucosides of paeony and nobiletin codelivered in a self-nanoemulsifying drug delivery system[J]. Acta Pharmacologica Sinica, 2022, 43(8), 2094-2108.
Authors:  Qu, Biao;  Wang, Xiao lin;  Zheng, De chong;  Mai, Chu tian;  Liu, Zhong qiu; et al.
Favorite | TC[WOS]:11 TC[Scopus]:10  IF:6.9/7.6 | Submit date：2023/01/30
Nobiletin  P-glycoprotein  Refractory Rheumatoid Arthritis  Self-nanoemulsifying Drug Delivery Systems  Total Glucosides Of Paeony