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Tauroursodeoxycholic Acid Reverses Dextran Sulfate Sodium-Induced Colitis in Mice via Modulation of Intestinal Barrier Dysfunction and Microbiome Dysregulation Journal article
Luo, Longbiao, Zhao, Yi, Zhang, Guangji, Dong, Sijing, Xu, Yin Yue, Shi, Hehe, Zhang, Menggai, Liu, Xue, Wang, Sicen, Luo, Hua, Jing, Wanghui. Tauroursodeoxycholic Acid Reverses Dextran Sulfate Sodium-Induced Colitis in Mice via Modulation of Intestinal Barrier Dysfunction and Microbiome Dysregulation[J]. Journal of Pharmacology and Experimental Therapeutics, 2024, 390(1), 116-124.
Authors:  Luo, Longbiao;  Zhao, Yi;  Zhang, Guangji;  Dong, Sijing;  Xu, Yin Yue; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.1/3.3 | Submit date：2024/07/04
Complex in vitro 3D models of digestive system tumors to advance precision medicine and drug testing: Progress, challenges, and trends Review article
2022
Authors:  Song, Sheng Lei;  Li, Bo;  Carvalho, Mariana R.;  Wang, Hui Jin;  Mao, De Li; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:12.0/12.5 | Submit date：2022/12/01
Cancer-on-a-chip  Digestive System Cancer  In Vitro 3d Models  Organoids  Tumor Microenvironment  
Applications of BGUSs inhibition in tumor prevention and chemotherapy Journal article
Wu RR(吴蓉蓉), Chen ZQ(陈智强), Jia YF(贾翼菲), Chen HQ(陈宏绮), Wang PP(王盼盼), Yan R(燕茹). Applications of BGUSs inhibition in tumor prevention and chemotherapy[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2021, 26(8), 964-974.
Authors:  Wu RR(吴蓉蓉);  Chen ZQ(陈智强);  Jia YF(贾翼菲);  Chen HQ(陈宏绮);  Wang PP(王盼盼); et al.
Favorite |  | Submit date：2022/07/31
Gut Microbiota  Β-glucuronidases  Cancer Risk  Chemotherapy  Gus Inhibitor  
Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Huang,Mu Yang, Jiang,Xiao Ming, Wang,Bing Lin, Sun,Yang, Lu,Jin Jian. Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms[J]. Pharmacology and Therapeutics, 2021, 219, 107694.
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
Favorite | TC[WOS]:88 TC[Scopus]:90  IF:12.0/12.5 | Submit date：2021/03/02
Challenge  Combination Therapy  Immunotherapy  Mechanism  Nsclc  Pd-1/pd-l1  
The sphingosine kinase-1/sphingosine-1-phosphate axis in cancer: Potential target for anticancer therapy Journal article
Zheng,Xiangjin, Li,Wan, Ren,Liwen, Liu,Jinyi, Pang,Xiaocong, Chen,Xiuping, Kang,De, Wang,Jinhua, Du,Guanhua. The sphingosine kinase-1/sphingosine-1-phosphate axis in cancer: Potential target for anticancer therapy[J]. Pharmacology and Therapeutics, 2018, 195, 85-99.
Authors:  Zheng,Xiangjin;  Li,Wan;  Ren,Liwen;  Liu,Jinyi;  Pang,Xiaocong; et al.
Favorite | TC[WOS]:84 TC[Scopus]:86  IF:12.0/12.5 | Submit date：2021/03/01
Cancer  Inhibitor  Mechanism  Sphingosine Kinase 1  
Berberine upregulates P-glycoprotein in human caco-2 cells and in an experimental model of colitis in the rat via activation of Nrf2-dependent mechanismss Journal article
Jing W., Safarpour Y., Zhang T., Guo P., Chen G., Wu X., Fu Q., Wang Y.. Berberine upregulates P-glycoprotein in human caco-2 cells and in an experimental model of colitis in the rat via activation of Nrf2-dependent mechanismss[J]. Journal of Pharmacology and Experimental Therapeutics, 2018, 366(2), 332.
Authors:  Jing W.;  Safarpour Y.;  Zhang T.;  Guo P.;  Chen G.; et al.
Favorite | TC[WOS]:47 TC[Scopus]:52  IF:3.1/3.3 | Submit date：2018/10/31
Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
Muhamad A. Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J. Piva, Robel Getachew, Yingnan Cao, Wenhua Zheng, Narin Osman, Peter J. Little. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2[J]. Journal of pharmacology and experimental therapeutics, 2018, 156-164.
Authors:  Muhamad A. Rostam;  Aravindra Shajimoon;  Danielle Kamato;  Partha Mitra;  Terrence J. Piva; et al.
Favorite |   IF:3.1/3.3 | Submit date：2022/08/31
Flavopiridol  Tgf-β  
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
Rostam, Muhamad A., Shajimoon, Aravindra, Kamato, Danielle, Mitra, Partha, Piva, Terrence J., Getachew, Robel, Cao, Yingnan, Zheng, Wenhua, Osman, Narin, Little, Peter J.. Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2[J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018, 365(1), 156-164.
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:24  IF:3.1/3.3 | Submit date：2018/10/30
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Rostam M.A., Shajimoon A., Kamato D., Mitra P., Piva T.J., Getachew R., Cao Y., Zheng W., Osman N., Little P.J.. Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2[J]. Journal of Pharmacology and Experimental Therapeutics, 2018, 365(1), 156-164.
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:24 | Submit date：2018/12/21
Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-kappa B Inhibition Journal article
Zou, Zheng-Qiang, Chen, Jia-Jia, Feng, Hong-Fang, Cheng, Yu-Fang, Wang, Hai-Tao, Zhou, Zhong-Zhen, Guo, Hai-Biao, Zheng, Wenhua, Xu, Jiang-Ping. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-kappa B Inhibition[J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2017, 362(1), 67-77.
Authors:  Zou, Zheng-Qiang;  Chen, Jia-Jia;  Feng, Hong-Fang;  Cheng, Yu-Fang;  Wang, Hai-Tao; et al.
Favorite | TC[WOS]:37 TC[Scopus]:40  IF:3.1/3.3 | Submit date：2018/10/30