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Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome Journal article
Pan, Zhijian, Yu, Chao Wu, Zhao, Chen, Shao, Min, Yang, Xuanjun, Liang, Xiaonan, Li, Haitao, Lu, Yucong, Ye, Qingqing, Chern, Ji Wang, Lu, Jiahong, Zhou, Hefeng, Lee, Simon Ming Yuen. Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome[J]. Toxicology and Applied Pharmacology, 2023, 480, 116745.
Authors:  Pan, Zhijian;  Yu, Chao Wu;  Zhao, Chen;  Shao, Min;  Yang, Xuanjun; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date:2024/01/02
Immunoproteasome  J24335  Lmp7  Parkinson's Disease  Protein Degradation  Α-synuclein  
Corrigendum to “Decabromodiphenyl ether-induced PRKACA hypermethylation contributed to glycolipid metabolism disorder via regulating PKA/AMPK pathway in rat and L-02 cells” [Environ. Toxicol. Pharmacol., 2022, 90, 103808] (Environmental Toxicology and Pharmacology (2022) 90, (S1382668922000011), (10.1016/j.etap.2022.103808)) Other
2023-10-01
Authors:  Zhu, Yupeng;  Jing, Li;  Li, Xiangyang;  Zhou, Guiqing;  Zhang, Yue; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date:2023/11/01
Corrigendum to “Decabromodiphenyl ether-induced PRKACA hypermethylation contributed to glycolipid metabolism disorder via regulating PKA/AMPK pathway in rat and L-02 cells” [Environ. Toxicol. Pharmacol., 2022, 90, 103808] (Environmental Toxicology and Pharmacology (2022) 90, (S1382668922000011), (10.1016/j.etap.2022.103808)) Other
2023-10-01
Authors:  Zhu, Yupeng;  Jing, Li;  Li, Xiangyang;  Zhou, Guiqing;  Zhang, Yue; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date:2023/11/01
Bulleyaconitine A is a sensitive substrate and competitive inhibitor of CYP3A4: One of the possible explanations for clinical adverse reactions Journal article
Li, Xiaocui, Ou, Xiaowen, Ni, Jiadong, Xu, Yihong, Zuo, Huilin, Fu, Yu, Yang, Caihua, Zhao, Zhongxiang, Li, Na, Zhou, Hua, Zhang, Rong, Liu, Zhongqiu, Fu, Ling, Zhu, Lijun. Bulleyaconitine A is a sensitive substrate and competitive inhibitor of CYP3A4: One of the possible explanations for clinical adverse reactions[J]. Toxicology and Applied Pharmacology, 2022, 445.
Authors:  Li, Xiaocui;  Ou, Xiaowen;  Ni, Jiadong;  Xu, Yihong;  Zuo, Huilin; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:3.3/3.6 | Submit date:2023/01/30
Adverse Reaction  Bulleyaconitine a  Cytochrome P450 Enzymes  Drug-drug Interactions  Human Liver Microsomes  Metabolism  
Decabromodiphenyl ether-induced PRKACA hypermethylation contributed to glycolipid metabolism disorder via regulating PKA/AMPK pathway in rat and L-02 cells Journal article
Zhu, Yupeng, Jing, Li, Li, Xiangyang, Zhou, Guiqing, Zhang, Yue, Sang, Yujian, Gao, Leqiang, Liu, Sitong, Shi, Zhixiong, Sun, Zhiwei, Ge, Wei, Zhou, Xianqing. Decabromodiphenyl ether-induced PRKACA hypermethylation contributed to glycolipid metabolism disorder via regulating PKA/AMPK pathway in rat and L-02 cells[J]. Environmental Toxicology and Pharmacology, 2022, 90(103808).
Authors:  Zhu, Yupeng;  Jing, Li;  Li, Xiangyang;  Zhou, Guiqing;  Zhang, Yue; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.2/4.4 | Submit date:2022/03/04
Decabromodiphenyl Ether  Glycolipid Metabolism  Pka/ampk Signaling Pathway  Prkaca  Dna Hypermethylation  
Improved up-and-down procedure for acute toxicity measurement with reliable LD50 verified by typical toxic alkaloids and modified Karber method Journal article
Zhang, Yan Yu, Huang, Yu Feng, Liang, Jie, Zhou, Hua. Improved up-and-down procedure for acute toxicity measurement with reliable LD50 verified by typical toxic alkaloids and modified Karber method[J]. BMC Pharmacology and Toxicology, 2022, 23(1).
Authors:  Zhang, Yan Yu;  Huang, Yu Feng;  Liang, Jie;  Zhou, Hua
Favorite | TC[WOS]:25 TC[Scopus]:26 | Submit date:2023/01/30
Acute Toxicity  Berberine Hydrochloride  Improved Up-and-down Procedure  Median Lethal Dose  Modified Karber Method  Nicotine  Sinomenine Hydrochloride  
Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells Journal article
Sun, Chong, Liu, Rong, Xia, Mengwei, Hou, Ying, Wang, Xumei, Lu, Jin jian, Liu, Bo, Chen, Xiuping. Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells[J]. Toxicology and Applied Pharmacology, 2021, 420, 115535.
Authors:  Sun, Chong;  Liu, Rong;  Xia, Mengwei;  Hou, Ying;  Wang, Xumei; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:3.3/3.6 | Submit date:2021/12/08
Emt  Lung Cancer  Metastasis  Nannocystin Ax  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Liu,Xin, Zhang,Yiying, ZHOU,Guang Ju, Hou,Ying, Kong,Qi, Lu,Jin Jian, Zhang,Qingwen, Chen,Xiuping. Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 404, 115179.
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:3.3/3.6 | Submit date:2021/03/01
Emt  Metastasis  Tgf-β1  Chinese Medicine  
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway Journal article
Li,Ao, Xiao,Xiao, Feng,Zhe Ling, Chen,Xiuping, Liu,Li Juan, Lin,Li Gen, Lu,Jin Jian, Zhang,Le Le. Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway[J]. Toxicology and Applied Pharmacology, 2020, 389, 114882.
Authors:  Li,Ao;  Xiao,Xiao;  Feng,Zhe Ling;  Chen,Xiuping;  Liu,Li Juan; et al.
Favorite | TC[WOS]:19 TC[Scopus]:21  IF:3.3/3.6 | Submit date:2021/03/01
Bleomycin  Fibrotic Process  Nagilactone d  Pulmonary Fibrosis  Tgf-β1  
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator Journal article
Xiao,Xiao, Li,Shuo, Zhang,Xiaoxun, Lu,Jinjian, Wang,Weiguang, Zhou,Shijia, Zhang,Jingyao, Wang,Rui, Li,Ao. HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator[J]. Toxicology and Applied Pharmacology, 2019, 373, 10-25.
Authors:  Xiao,Xiao;  Li,Shuo;  Zhang,Xiaoxun;  Lu,Jinjian;  Wang,Weiguang; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:3.3/3.6 | Submit date:2021/03/02
Breast Cancer Cells  Glucose Deprivation  Glucose-regulated Protein 78  Hhq-4  Unfolded Protein Response