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Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis Journal article
Hu, Xin Yue, Luo, Hui Juan, Wei, Xin, Wang, Yu Zhuo, Ye, Yan Song, Wan, Shi Jie, Zheng, Dan, Zhou, Yu, Xu, Hong Xi, Li, Xing Ren, Lin, Li Gen, Xu, Gang. Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis[J]. Bioorganic Chemistry, 2024, 153, 107864.
Authors:  Hu, Xin Yue;  Luo, Hui Juan;  Wei, Xin;  Wang, Yu Zhuo;  Ye, Yan Song; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.5/4.7 | Submit date：2024/11/05
1l-1β  Anti-inflammatory Activity  Bpap  Garcinia Yunnanensis  Nlrp3  
Polycyclic polyprenylated acylphloroglucinols from the pericarps of Garcinia multiflora champ. ex Benth. with cytotoxic property Journal article
Cao, Jun, Lyu, Wen Yu, Zhang, Yujia, Su, Zhicheng, Li, Ting, Zhang, Qingwen, Gan, Lishe, Lu, Jin Jian, Lin, Ligen. Polycyclic polyprenylated acylphloroglucinols from the pericarps of Garcinia multiflora champ. ex Benth. with cytotoxic property[J]. Phytochemistry, 2024, 228, 114242.
Authors:  Cao, Jun;  Lyu, Wen Yu;  Zhang, Yujia;  Su, Zhicheng;  Li, Ting; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.2/3.4 | Submit date：2024/09/03
Apoptosis  Cell Cycle Arrest  Clusiaceae  Cytotoxicity  Garcinia Multiflora  Polycyclic Polyprenylated Acylphloroglucinols  
Bioactivity-based molecular networking guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate Presentation
会议地点: Belgrade, Serbia, 会议日期: 22/10/2024-24/10/2024, 报告日期: 2024-10-01
Authors:  LIN LIGEN
Favorite |  | Submit date：2024/10/18
诱导脂肪褐变小分子靶向递送系统的设计与合成，及其改善肥胖的作用研究 Conference paper
Chen Qiyan, Zhou Fei, LIN LIGEN. 诱导脂肪褐变小分子靶向递送系统的设计与合成，及其改善肥胖的作用研究[C], 2024.
Authors:  Chen Qiyan;  Zhou Fei;  LIN LIGEN
Favorite |  | Submit date：2024/10/18
Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB Journal article
Linghu, Kegang, Cui, Wenqing, Li, Taiqin, Tuo, Yueting, Wang, Dasong, Pan, Huiqi, Zhang, Tian, Lin, Ligen, Yu, Hua, Hu, Xiaoxia, Li, Haiyang, Shen, Xiangchun. Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB[J]. Acta Pharmaceutica Sinica B, 2024, 14(8), 3561-3575.
Authors:  ; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:14.7/14.1 | Submit date：2024/05/16
A-methylene-g-  Butyrolactone  Rheumatoid Arthritis  Nf-kb P65  Synovial  Microenvironment  Sesquiterpene Lactones  
SIRT3 and NAFLD: hit two or more birds with one stone Presentation
会议地点: Institute of Materia Medica, CAMS, Beijing, 报告日期: 2024-07-01
Authors:  LIN LIGEN
Favorite |  | Submit date：2024/07/29
Myricanol prevents aging-related Sarcopenia via targeting peroxiredoxin 5 and Nampt Conference paper
LIN LIGEN. Myricanol prevents aging-related Sarcopenia via targeting peroxiredoxin 5 and Nampt[C], 2024.
Authors:  LIN LIGEN
Favorite |  | Submit date：2024/07/29
Strategies to discover lead compounds from traditional Chinese medicine Presentation
会议地点: 广东江门中医药职业学院, Jiangmen, 报告日期: 2024-06-01
Authors:  LIN LIGEN
Favorite |  | Submit date：2024/07/29
Myricanol prevents aging-related sarcopenia by rescuing mitochondrial dysfunction via targeting peroxiredoxin 5 Journal article
Shen, Shengnan, Liao, Qiwen, Lyu, Peng, Wang, Jigang, Lin, Ligen. Myricanol prevents aging-related sarcopenia by rescuing mitochondrial dysfunction via targeting peroxiredoxin 5[J]. MedComm, 2024, 5(6), e566.
Authors:  Shen, Shengnan;  Liao, Qiwen;  Lyu, Peng;  Wang, Jigang;  Lin, Ligen
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2024/07/04
Healthy Aging  Mitochondria  Myricanol  Peroxiredoxin 5  Redox Homeostasis  Sarcopenia  
Exosomal miRNA-155-5p from M1-polarized macrophages interrupt diabetic wound healing Conference paper
Lou Ruohan, Chen Jiali, LIN LIGEN. Exosomal miRNA-155-5p from M1-polarized macrophages interrupt diabetic wound healing[C], 2024.
Authors:  Lou Ruohan;  Chen Jiali;  LIN LIGEN
Favorite |  | Submit date：2024/07/29