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Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Botkjaer K.A., Kwok H.F., Terp M.G., Karatt-Vellatt A., Santamaria S., McCafferty J., Andreasen P.A., Itoh Y., Ditzel H.J., Murphy G.. Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo[J]. Oncotarget, 2016, 7(13), 16773-16792.
Authors:  Botkjaer K.A.;  Kwok H.F.;  Terp M.G.;  Karatt-Vellatt A.;  Santamaria S.; et al.
Favorite | TC[WOS]:33 TC[Scopus]:34 | Submit date：2018/12/19
Antibody  In Vivo targetIng  Metastasis  Mt1-mmp  Non-catalytic Sites  
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Botkjaer, K.A., Kwok, H. F., Terp, M.G., Karatt-Vellatt, A., Santamaria, S., McCafferty, J., Andreasen, P.A., Itoh, Y., Ditzel, H.J., Murphy, G.. Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo[J]. Oncotarget, 2016, 1-20.
Authors:  Botkjaer, K.A.;  Kwok, H. F.;  Terp, M.G.;  Karatt-Vellatt, A.;  Santamaria, S.; et al.
Favorite |   IF:5.168/5.312 | Submit date：2022/06/02
MT1-MMP  antibody  non-catalytic sites  in vivo targeting  metastasis  
Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy Journal article
Kwok H.F., Botkjaer K.A., Tape C.J., Huang Y., McCafferty J., Murphy G.. Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy[J]. Protein engineering, design & selection : PEDS Oxford University Press, 2014, 27(6), 179-190.
Authors:  Kwok H.F.;  Botkjaer K.A.;  Tape C.J.;  Huang Y.;  McCafferty J.; et al.
Favorite | TC[WOS]:29 TC[Scopus]:30 | Submit date：2018/12/19
Anti-tace Antibody  Exosite  Immunoreactivity  Phage-display Randomization Libraries  Sub-nanomolar Affinity