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BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance Journal article
Xiaodong Shu, Jianjie Li, Un In Chan, Sek Man Su, Changxiang Shi, Xin Zhang, Tingting An, Jun Xu, Lihua Mo, Jianlin Liu, Yuqing Wang, Xiaoling Li, Min Deng, Josh Haipeng Lei, Chunfei Wang, Hao Tian, Sun Heng, Joong Sup Shim, Xuanjun Zhang, Yunlu Dai, Zhicheng Yao, Xiaying Kuang, Ying Lin, Chu-Xia Deng, Xiaoling Xu. BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance[J]. CANCER RESEARCH, 2023, 83(15), 2614-2633.
Authors:  Xiaodong Shu;  Jianjie Li;  Un In Chan;  Sek Man Su;  Changxiang Shi; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:12.5/11.6 | Submit date：2023/08/30
An ultrasensitive fluorescent breath ammonia sensor for noninvasive diagnosis of chronic kidney disease and helicobacter pylori infection Journal article
Song, Guangjie, Jiang, Di, Wu, Jianchang, Sun, Xiangzhong, Deng, Mengyu, Wang, Lei, Hao, Changxiang, Shi, Jiayan, Liu, Hongtian, Tian, Yanqing, Chen, Meiwan. An ultrasensitive fluorescent breath ammonia sensor for noninvasive diagnosis of chronic kidney disease and helicobacter pylori infection[J]. Chemical Engineering Journal, 2022, 440, 135979.
Authors:  Song, Guangjie;  Jiang, Di;  Wu, Jianchang;  Sun, Xiangzhong;  Deng, Mengyu; et al.
Favorite | TC[WOS]:42 TC[Scopus]:42  IF:13.3/13.2 | Submit date：2022/05/13
Breath Ammonia  Chronic Kidney Disease  Fluorescence Sensor  Helicobacter Pylori  Non-invasive Diagnosis  
Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation Journal article
Changxiang Shi, Shishi Tao, Guowen Ren, Eun Ju Yang, Xiaodong Shu, Pui Kei Mou, Yifan Liu, Yongjun Dang, Xiaoling Xu, Joong Sup Shim. Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation[J]. Oncogene, 2022, 41(19), 2734-2748.
Authors:  Changxiang Shi;  Shishi Tao;  Guowen Ren;  Eun Ju Yang;  Xiaodong Shu; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.9/7.5 | Submit date：2022/05/31
Natural products targeting cancer cell dependency Review article
2021
Authors:  Changxiang Shi;  Eun Ju Yang;  Shishi Tao;  Guowen Ren;  Pui Kei Mou; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:2.1/2.5 | Submit date：2021/12/08
Aurora kinase A, a synthetic lethal target for precision cancer medicine Review article
2021
Authors:  Mou, Pui Kei;  Yang, Eun Ju;  Shi, Changxiang;  Ren, Guowen;  Tao, Shishi; et al.
Favorite | TC[WOS]:63 TC[Scopus]:63  IF:9.5/11.7 | Submit date：2021/12/07
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Shi,Changxiang, Yang,Eun Ju, Liu,Yifan, Mou,Pui Kei, Ren,Guowen, Shim,Joong Sup. Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression[J]. Oncogene, 2021, 40(5), 937-950.
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:6.9/7.5 | Submit date：2021/03/04
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics Journal article
Lyu,Junfang, Yang,Eun Ju, Zhang,Baoyuan, Wu,Changjie, Pardeshi,Lakhansing, Shi,Changxiang, Mou,Pui Kei, Liu,Yifan, Tan,Kaeling, Shim,Joong Sup. Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics[J]. Nature Communications, 2020, 11(1), 5105.
Authors:  Lyu,Junfang;  Yang,Eun Ju;  Zhang,Baoyuan;  Wu,Changjie;  Pardeshi,Lakhansing; et al.
Favorite | TC[WOS]:37 TC[Scopus]:36  IF:14.7/16.1 | Submit date：2021/03/04
Histone acetyltransferase (HAT) P300/CBP inhibitors induce synthetic lethality in pten-deficient colorectal cancer cells through destabilizing AKT Journal article
Liu,Yifan, Yang,Eun Ju, Shi,Changxiang, Mou,Pui Kei, Zhang,Baoyuan, Wu,Changjie, Lyu,Junfang, Shim,Joong Sup. Histone acetyltransferase (HAT) P300/CBP inhibitors induce synthetic lethality in pten-deficient colorectal cancer cells through destabilizing AKT[J]. International Journal of Biological Sciences, 2020, 16(11), 1774-1784.
Authors:  Liu,Yifan;  Yang,Eun Ju;  Shi,Changxiang;  Mou,Pui Kei;  Zhang,Baoyuan; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:8.2/8.3 | Submit date：2021/03/04
Akt  Anacardic Acid  Histone Acetyltransferases  Hsp70  Pten  Synthetic Lethality  
Dual pH and oxygen luminescent nanoprobes based on graft polymers for extracellular metabolism monitoring and intracellular imaging Journal article
Tingting Pan, Cheng Yang, Jiayan Shi, Changxiang Hao, Yuan Qiao, Jiaze Li, Mengyu Deng, Yanqing Tian, Meiwan Chen. Dual pH and oxygen luminescent nanoprobes based on graft polymers for extracellular metabolism monitoring and intracellular imaging[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2019, 291, 306-318.
Authors:  Tingting Pan;  Cheng Yang;  Jiayan Shi;  Changxiang Hao;  Yuan Qiao; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:8.0/7.0 | Submit date：2020/01/07
Dual Ph And Oxygen Probes  Amphiphilic Graft Copolymers  Nanoprobes  Extracellular Sensing  Intracellular Imaging