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Design of novel analogues of t-DPH1 with reduced cytotoxicity, taking the three conserved characteristics of the dermaseptin family as the feasible starting point Journal article
Qin, Haixin, Zuo, Weimin, Luo, Siyuan, Ge, Lilin, Wang, Lei, Chen, Xiaoling, Ma, Chengbang, Li, Hong Ye, Chen, Tianbao, Zhou, Mei, Kwok, Hang Fai. Design of novel analogues of t-DPH1 with reduced cytotoxicity, taking the three conserved characteristics of the dermaseptin family as the feasible starting point[J]. Arabian Journal of Chemistry, 2024, 17(1), 105420.
Authors:  Qin, Haixin;  Zuo, Weimin;  Luo, Siyuan;  Ge, Lilin;  Wang, Lei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.3/5.6 | Submit date：2024/02/22
Antibiotic And Antiancer Protoype Drug  Antimicrobial Peptide  C. Elegans  Dermaseptin Peptide  Peptide Cytotoxicity  Peptide Modification  
Discovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue Journal article
Qin,Haixin, Zuo,Weimin, Ge,Lilin, Siu,Shirley W.I., Wang,Lei, Chen,Xiaoling, Ma,Chengbang, Chen,Tianbao, Zhou,Mei, Cao,Zhijian, Kwok,Hang Fai. Discovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue[J]. Computational and Structural Biotechnology Journal, 2023, 21, 2960-2972.
Authors:  Qin,Haixin;  Zuo,Weimin;  Ge,Lilin;  Siu,Shirley W.I.;  Wang,Lei; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.4/5.0 | Submit date：2023/08/03
Anticancer Peptide  Antimicrobial Peptide  Brevinin Peptide  Molecular Dynamic Simulation  Peptide Modification  
In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug Journal article
Ye, Zhuming, Zhou, Xiaowei, Xi, Xinping, Zai, Yu, Zhou, Mei, Chen, Xiaoling, Ma, Chengbang, Chen, Tianbao, Wang, Lei, Kwok, Hang Fai. In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug[J]. Pharmaceutics, 2022, 14(3), 604.
Authors:  Ye, Zhuming;  Zhou, Xiaowei;  Xi, Xinping;  Zai, Yu;  Zhou, Mei; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:4.9/5.5 | Submit date：2022/03/28
Antimicrobial Activity  Branched Peptide  Galleria Mellonella Larva Model  Temporin  
Structure–activity relationship and molecular docking of a Kunitz-like trypsin inhibitor, Kunitzin-ah, from the skin secretion of Amolops hainanensis Journal article
Chen, Yuqing, Xi, Xinping, Ma, Chengbang, Zhou, Mei, Chen, Xiaoling, Ye, Zhuming, Ge, Lilin, Wu, Qinan, Chen, Tianbao, Wang, Lei, Kwok, Hang Fai. Structure–activity relationship and molecular docking of a Kunitz-like trypsin inhibitor, Kunitzin-ah, from the skin secretion of Amolops hainanensis[J]. Pharmaceutics, 2021, 13(7), 966.
Authors:  Chen, Yuqing;  Xi, Xinping;  Ma, Chengbang;  Zhou, Mei;  Chen, Xiaoling; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:4.9/5.5 | Submit date：2021/12/08
Kunitz-like Trypsin Inhibitors  Molecular Docking  Structure–activity Relationship  
Aggregation and its influence on the bioactivities of a novel antimicrobial peptide, temporin-pf, and its analogues Journal article
Yu Zai, Xinping Xi, Zhuming Ye, Chengbang Ma, Mei Zhou, Xiaoling Chen, Shirley W.I. Siu, Tianbao Chen, Lei Wang, Hang Fai Kwok. Aggregation and its influence on the bioactivities of a novel antimicrobial peptide, temporin-pf, and its analogues[J]. International Journal of Molecular Sciences, 2021, 22(9), 4509.
Authors:  Yu Zai;  Xinping Xi;  Zhuming Ye;  Chengbang Ma;  Mei Zhou; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26 | Submit date：2021/12/07
Antimicrobial Activity  Md Simulation  Peptide Aggregation  Temporin  
A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway Journal article
Wei, Ran, Wu, Qiushuang, Ai, Nana, Wang, Lei, Zhou, Mei, Shaw, Chris, Chen, Tianbao, Ye, Richard Dequan, Ge, Wei, Siu, Shirley W.I., Kwok, Hang Fai. A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway[J]. Computational and Structural Biotechnology Journal, 2021, 19, 2664-2675.
Authors:  Wei, Ran;  Wu, Qiushuang;  Ai, Nana;  Wang, Lei;  Zhou, Mei; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.4/5.0 | Submit date：2021/09/17
Anti-angiogenesis  Chromogranin a  Vasostatin-1  Vegfr2  
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from the Skin Secretion of Odorrana schmackeri Journal article
Zhou,Xiaowei, Liu,Yue, Gao,Yitian, Wang,Yuanxing, Xia,Qiang, Zhong,Ruimin, Ma,Chengbang, Zhou,Mei, Xi,Xinping, Shaw,Chris, Chen,Tianbao, Wu,Di, Kwok,Hang Fai, Wang,Lei. Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from the Skin Secretion of Odorrana schmackeri[J]. Toxins, 2020, 12(8).
Authors:  Zhou,Xiaowei;  Liu,Yue;  Gao,Yitian;  Wang,Yuanxing;  Xia,Qiang; et al.
Favorite | TC[WOS]:24 TC[Scopus]:25  IF:3.9/4.2 | Submit date：2021/03/04
Antimicrobial Activity  Skin-derived Peptides  Stability  Waxworm Model  
Pharmacological effects of a novel bradykinin-related peptide (RR-18) from the skin secretion of the hejiang frog (Ordorrana hejiangensis) on smooth muscle Journal article
Zhou,Xiaowei, Xu,Jie, Zhong,Ruimin, Ma,Chengbang, Zhou,Mei, Cao,Zhijian, Xi,Xinping, Shaw,Chris, Chen,Tianbao, Wang,Lei, Kwok,Hang Fai. Pharmacological effects of a novel bradykinin-related peptide (RR-18) from the skin secretion of the hejiang frog (Ordorrana hejiangensis) on smooth muscle[J]. Biomedicines, 2020, 8(7), 225.
Authors:  Zhou,Xiaowei;  Xu,Jie;  Zhong,Ruimin;  Ma,Chengbang;  Zhou,Mei; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.9/4.1 | Submit date：2021/03/04
Antagonist  Bradykinin Related Peptide  Frog  Skin Secretion  Smooth Muscle  
LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi Journal article
Bin Li, Peng Lyu, Shuping Xie, Haixin Qin, Wenyuan Pu, Houxi Xu, Tianbao Chen, Chris Shaw, Lilin Ge, Hang Fai Kwok. LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi[J]. BIOMOLECULES, 2019, 9(6).
Authors:  Bin Li;  Peng Lyu;  Shuping Xie;  Haixin Qin;  Wenyuan Pu; et al.
Favorite | TC[WOS]:20 TC[Scopus]:22  IF:4.8/5.4 | Submit date：2020/05/20
Amphibian  Brevinin-like Peptide  Antimicrobial Peptides  Drug Discovery  
Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and Its Truncated Analogues Journal article
Xiaowei Zhou, Daning Shi, Ruimin Zhong, Zhuming Ye, Chengbang Ma, Mei Zhou, Xinping Xi, Lei Wang, Tianbao Chen, Hang Fai Kwok. Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and Its Truncated Analogues[J]. BIOMOLECULES, 2019, 9(6).
Authors:  Xiaowei Zhou;  Daning Shi;  Ruimin Zhong;  Zhuming Ye;  Chengbang Ma; et al.
Favorite | TC[WOS]:19 TC[Scopus]:20  IF:4.8/5.4 | Submit date：2020/05/20
Ranatuerin  Antimicrobial Peptides  Α-helix  Membrane Permeability  Waxworm Model