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Toosendanin, a novel potent vacuolar-type H+-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy Journal article
Dong, Yu, Zhu, Guoyuan, Wang, Sheng Fang, Keon, Kristine A., Rubinstein, John L., Zeng, Si Xin, Zhang, Shuang, Chen, Qiu Ling, Fu, Jing, Li, Min, Shen, Han Ming, Lu, Jin Jian, Chen, Xiu Ping, Lu, Jia Hong. Toosendanin, a novel potent vacuolar-type H+-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy[J]. International Journal of Biological Sciences, 2022, 18(7), 2684-2702.
Authors:  Dong, Yu;  Zhu, Guoyuan;  Wang, Sheng Fang;  Keon, Kristine A.;  Rubinstein, John L.; et al.
Favorite | TC[WOS]:18 TC[Scopus]:19  IF:8.2/8.3 | Submit date:2022/07/20
Toosendanin  V-atpase Inhibitor  Autophagy Inhibitor  Protective Autophagy  Anti-cancer Effect  
Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach Journal article
Song,Min, Zhang,Jian, Chan,Ging, Hou,Ying, Chen,Xiu Ping, Zhang,Xiao Qi, Ye,Wen Cai, Zhang,Qing Wen. Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach[J]. Journal of Natural Products, 2020, 83(12), 3502-3510.
Authors:  Song,Min;  Zhang,Jian;  Chan,Ging;  Hou,Ying;  Chen,Xiu Ping; et al.
Favorite | TC[WOS]:9 TC[Scopus]:10  IF:3.3/3.9 | Submit date:2021/03/01
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Jiang,Xiao ming, Xu,Yu lian, Yuan,Luo wei, Zhang,Le le, Huang,Mu yang, Ye,Zi han, Su,Min xia, Chen,Xiu ping, Zhu,Hong, Ye,Richard D., Lu,Jin jian. TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance[J]. Acta Pharmacologica Sinica, 2020, 42(3), 451-459.
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang; et al.
Favorite | TC[WOS]:40 TC[Scopus]:39  IF:6.9/7.6 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Emt  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
CHEN,Yu Chi, HUANG,Mu Yang, ZHANG,Le Le, FENG,Zhe Ling, JIANG,Xiao Ming, YUAN,Luo Wei, HUANG,Run Yue, LIU,Bo, YU,Hua, WANG,Yi Tao, CHEN,Xiu Ping, LIN,Li Gen, LU,Jin Jian. Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells[J]. Chinese Journal of Natural Medicines, 2020, 18(7), 517-525.
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:4.0/3.7 | Submit date:2021/03/01
Programmed Death Ligand 1  Nagilactone e  Lung Cancer  C-jun  Jnk  
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Zhang,Le le, Guo,Jing, Jiang,Xiao ming, Chen,Xiu ping, Wang,Yi tao, Li,Ao, Lin,Li gen, Li,Hua, Lu,Jin jian. Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity[J]. Acta Pharmacologica Sinica, 2020, 41(5), 698-705.
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:6.9/7.6 | Submit date:2021/03/01
Nagilactone e  Diterpenoids  Human Lung Cancer A549 Cell Line Xenograft  Rna-seq  Cmap  Click-it  Molecular Docking  Riok2  Protein Synthesis Inhibitor  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Cai,Cui Zan, Zhou,He Feng, Yuan,Ning Ning, Wu,Ming Yue, Lee,Simon Ming Yuen, Ren,Jiao Yan, Su,Huan Xing, Lu,Jin Jian, Chen,Xiu Ping, Li,Min, Tan,Jie Qiong, Lu,Jia Hong. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation[J]. Phytomedicine, 2019, 61.
Authors:  Cai,Cui Zan;  Zhou,He Feng;  Yuan,Ning Ning;  Wu,Ming Yue;  Lee,Simon Ming Yuen; et al.
Favorite | TC[WOS]:34 TC[Scopus]:38  IF:6.7/6.2 | Submit date:2021/03/01
-synuclein  Harmine  Parkinson's Disease  Protein Kinase a  Ubiquitin-proteasome System  
Cissampelini Methiodidum Book chapter
出自: Natural Small Molecule Drugs from Plants, 2018, 页码:215-220
Authors:  Yu,Jie;  Du,Li Da;  Chen,Xiu Ping;  Wang,Shou Bao;  Du,Guan Hua
Favorite | TC[Scopus]:0 | Submit date:2021/03/01
Alkaloid  Cissampelini Methiodidum  Muscle relaxant  
Shikonin Book chapter
出自: Natural Small Molecule Drugs from Plants:Singapore : Springer Singapore : Imprint: Springer, 2018, 页码:731-736
Authors:  Sun,Wen;  Du,Li Da;  Wang,Shou Bao;  Chen,Xiu Ping;  Du,Guan Hua
Favorite | TC[Scopus]:3 | Submit date:2021/03/01
Anti-inflammatory  Arnebia Euchroma (Royle) Johnst  Shikonin