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Toosendanin, a novel potent vacuolar-type H+-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy
Journal article
Dong, Yu, Zhu, Guoyuan, Wang, Sheng Fang, Keon, Kristine A., Rubinstein, John L., Zeng, Si Xin, Zhang, Shuang, Chen, Qiu Ling, Fu, Jing, Li, Min, Shen, Han Ming, Lu, Jin Jian, Chen, Xiu Ping, Lu, Jia Hong. Toosendanin, a novel potent vacuolar-type H+-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy[J]. International Journal of Biological Sciences, 2022, 18(7), 2684-2702.
Authors:
Dong, Yu
;
Zhu, Guoyuan
;
Wang, Sheng Fang
;
Keon, Kristine A.
;
Rubinstein, John L.
; et al.
Favorite
|
TC[WOS]:
18
TC[Scopus]:
19
IF:
8.2
/
8.3
|
Submit date:2022/07/20
Toosendanin
V-atpase Inhibitor
Autophagy Inhibitor
Protective Autophagy
Anti-cancer Effect
Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach
Journal article
Song,Min, Zhang,Jian, Chan,Ging, Hou,Ying, Chen,Xiu Ping, Zhang,Xiao Qi, Ye,Wen Cai, Zhang,Qing Wen. Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach[J]. Journal of Natural Products, 2020, 83(12), 3502-3510.
Authors:
Song,Min
;
Zhang,Jian
;
Chan,Ging
;
Hou,Ying
;
Chen,Xiu Ping
; et al.
Favorite
|
TC[WOS]:
9
TC[Scopus]:
10
IF:
3.3
/
3.9
|
Submit date:2021/03/01
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance
Journal article
Jiang,Xiao ming, Xu,Yu lian, Yuan,Luo wei, Zhang,Le le, Huang,Mu yang, Ye,Zi han, Su,Min xia, Chen,Xiu ping, Zhu,Hong, Ye,Richard D., Lu,Jin jian. TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance[J]. Acta Pharmacologica Sinica, 2020, 42(3), 451-459.
Authors:
Jiang,Xiao ming
;
Xu,Yu lian
;
Yuan,Luo wei
;
Zhang,Le le
;
Huang,Mu yang
; et al.
Favorite
|
TC[WOS]:
40
TC[Scopus]:
39
IF:
6.9
/
7.6
|
Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer
Emt
Nf-κb
Osimertinib Resistance
Tgfβ2
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells
Journal article
CHEN,Yu Chi, HUANG,Mu Yang, ZHANG,Le Le, FENG,Zhe Ling, JIANG,Xiao Ming, YUAN,Luo Wei, HUANG,Run Yue, LIU,Bo, YU,Hua, WANG,Yi Tao, CHEN,Xiu Ping, LIN,Li Gen, LU,Jin Jian. Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells[J]. Chinese Journal of Natural Medicines, 2020, 18(7), 517-525.
Authors:
CHEN,Yu Chi
;
HUANG,Mu Yang
;
ZHANG,Le Le
;
FENG,Zhe Ling
;
JIANG,Xiao Ming
; et al.
Favorite
|
TC[WOS]:
15
TC[Scopus]:
15
IF:
4.0
/
3.7
|
Submit date:2021/03/01
Programmed Death Ligand 1
Nagilactone e
Lung Cancer
C-jun
Jnk
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity
Journal article
Zhang,Le le, Guo,Jing, Jiang,Xiao ming, Chen,Xiu ping, Wang,Yi tao, Li,Ao, Lin,Li gen, Li,Hua, Lu,Jin jian. Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity[J]. Acta Pharmacologica Sinica, 2020, 41(5), 698-705.
Authors:
Zhang,Le le
;
Guo,Jing
;
Jiang,Xiao ming
;
Chen,Xiu ping
;
Wang,Yi tao
; et al.
Favorite
|
TC[WOS]:
14
TC[Scopus]:
14
IF:
6.9
/
7.6
|
Submit date:2021/03/01
Nagilactone e
Diterpenoids
Human Lung Cancer A549 Cell Line Xenograft
Rna-seq
Cmap
Click-it
Molecular Docking
Riok2
Protein Synthesis Inhibitor
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation
Journal article
Cai,Cui Zan, Zhou,He Feng, Yuan,Ning Ning, Wu,Ming Yue, Lee,Simon Ming Yuen, Ren,Jiao Yan, Su,Huan Xing, Lu,Jin Jian, Chen,Xiu Ping, Li,Min, Tan,Jie Qiong, Lu,Jia Hong. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation[J]. Phytomedicine, 2019, 61.
Authors:
Cai,Cui Zan
;
Zhou,He Feng
;
Yuan,Ning Ning
;
Wu,Ming Yue
;
Lee,Simon Ming Yuen
; et al.
Favorite
|
TC[WOS]:
34
TC[Scopus]:
38
IF:
6.7
/
6.2
|
Submit date:2021/03/01
-synuclein
Harmine
Parkinson's Disease
Protein Kinase a
Ubiquitin-proteasome System
Cissampelini Methiodidum
Book chapter
出自: Natural Small Molecule Drugs from Plants, 2018, 页码:215-220
Authors:
Yu,Jie
;
Du,Li Da
;
Chen,Xiu Ping
;
Wang,Shou Bao
;
Du,Guan Hua
Favorite
|
TC[Scopus]:
0
|
Submit date:2021/03/01
Alkaloid
Cissampelini Methiodidum
Muscle relaxant
Shikonin
Book chapter
出自: Natural Small Molecule Drugs from Plants:Singapore : Springer Singapore : Imprint: Springer, 2018, 页码:731-736
Authors:
Sun,Wen
;
Du,Li Da
;
Wang,Shou Bao
;
Chen,Xiu Ping
;
Du,Guan Hua
Favorite
|
TC[Scopus]:
3
|
Submit date:2021/03/01
Anti-inflammatory
Arnebia Euchroma (Royle) Johnst
Shikonin