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N-terminal α-amino group modification of antibodies using a site-selective click chemistry method Journal article
Li, D., Han, B., Wei, R., Yao, G., Chen, Z., Liu, J., Poon, C. W., Su, W., Zhu, Z., Dimitrov, D., Zhao, Q.. N-terminal α-amino group modification of antibodies using a site-selective click chemistry method[J]. mAbs, 2018, 712-719.
Authors:  Li, D.;  Han, B.;  Wei, R.;  Yao, G.;  Chen, Z.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26  IF:5.6/5.8 | Submit date：2022/08/31
Antibody  Antibody Engineering  Antibody-drug Conjugate  Clickchemistry  Site-specific Modification  
Engineered antibody CH2 domains binding to nucleolin: isolation, characterization and improvement of aggregation Journal article
Li, D., Gong, R., Zheng, J., Chen, X., Dimitrov, D., Zhao, Q.. Engineered antibody CH2 domains binding to nucleolin: isolation, characterization and improvement of aggregation[J]. Biochemical and Biophysical Research Communications, 2017, 446-453.
Authors:  Li, D.;  Gong, R.;  Zheng, J.;  Chen, X.;  Dimitrov, D.; et al.
Favorite |   IF:2.5/2.7 | Submit date：2023/08/30
antibody domain  CH2  nucleolin  yeast display  monoclonal antibody  aggregation prone region  
A dual‐specific anti‐IGF‐1/IGF‐2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma Journal article
Zhao, Q., Tran, H., Dimitrov, D., Cheung, N.. A dual‐specific anti‐IGF‐1/IGF‐2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma[J]. International Journal of Cancer, 2015, 2243-2252.
Authors:  Zhao, Q.;  Tran, H.;  Dimitrov, D.;  Cheung, N.
Favorite |   IF:5.7/6.0 | Submit date：2023/08/30
IGF-1  IGF-2  chemotherapy  neuroblastoma  temsirolimus  
A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaques Journal article
Feng, Y., Zhao, Q., Chen, W., Wang, Y., Crowder, K., Dimitrov, D.. A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaques[J]. Experimental and molecular pathology, 2014, 359-367.
Authors:  Feng, Y.;  Zhao, Q.;  Chen, W.;  Wang, Y.;  Crowder, K.; et al.
Favorite |   IF:2.8/2.7 | Submit date：2023/08/30
Bispecific antibodies  Cynomolgus macaques  Half-life  IGF ligand.  
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies Journal article
Zhu, Z., Qin, H., Chen, W., Zhao, Q., Shen, X., Schutte, R., Wang, Y., Ofek, G., Streaker, E., Prabakaran, P., Fouda, G., Liao, H., Owens, J., Louder, M., Yang, Y., Klaric, K., Moody, M., Mascola, J., Scott, J., Kwong, P., Montefiori, D., Haynes, B., Tomaras, G., Dimitrov, D.. Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies[J]. Journal of Virology, 2011, 11401-11408.
Authors:  Zhu, Z.;  Qin, H.;  Chen, W.;  Zhao, Q.;  Shen, X.; et al.
Favorite |   IF:4.0/4.0 | Submit date：2023/08/30
HIV-1  neutralizing antibody  2F5-like antibodies  
Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens Journal article
Chen, W., Feng, Y., Gong, R., Zhu, Z., Wang, Y., Zhao, Q., Dimitrov, D.. Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens[J]. Journal of virology, 2011, 9395-9405.
Authors:  Chen, W.;  Feng, Y.;  Gong, R.;  Zhu, Z.;  Wang, Y.; et al.
Favorite |   IF:4.0/4.0 | Submit date：2023/08/30
CD4  HIV-1  vaccine immunogen  
Human monoclonal antibody fragments binding to insulin-like growth factors I and II with picomolar affinity Journal article
Zhao, Q., Feng, Y., Zhu, Z., Dimitrov, D.. Human monoclonal antibody fragments binding to insulin-like growth factors I and II with picomolar affinity[J]. Molecular cancer therapeutics, 2011, 1677-1685.
Authors:  Zhao, Q.;  Feng, Y.;  Zhu, Z.;  Dimitrov, D.
Favorite |   IF:5.3/5.4 | Submit date：2023/08/30
monoclonal antibody  IGF-I  IGF-II  
Shortened engineered human antibody CH2 domains increased stability and binding to the human neonatal Fc receptor Journal article
Gong, R., Wang, Y., Feng, Y., Zhao, Q., Dimitrov, D.. Shortened engineered human antibody CH2 domains increased stability and binding to the human neonatal Fc receptor[J]. Journal of Biological Chemistry, 2011, 27288-27293.
Authors:  Gong, R.;  Wang, Y.;  Feng, Y.;  Zhao, Q.;  Dimitrov, D.
Favorite |   IF:4.0/4.4 | Submit date：2023/08/30
Antibodies  CH2  engineered antibody domains  Fc neonatal receptor  
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies Journal article
Zhongyu Zhu, Haiyan Rebekah Qin, Weizao Chen, Qi Zhao, Xiaoying Shen, Robert Schutte, Yanping Wang, Gilad Ofek, Emily Streaker, Ponraj Prabakaran, Genevieve G. Fouda, Hua-Xin Liao, John Owens, Mark Louder, Yongping Yang, Kristina-Ana Klaric, M. Anthony Moody, John R. Mascola, Jamie K. Scott, Peter D. Kwong, David Montefiori, Barton F. Haynes, Georgia D. Tomaras, Dimiter S. Dimitrov. Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies[J]. JOURNAL OF VIROLOGY, 2011, 85(21), 11401-11408.
Authors:  Zhongyu Zhu;  Haiyan Rebekah Qin;  Weizao Chen;  Qi Zhao;  Xiaoying Shen; et al.
Favorite | TC[WOS]:72 TC[Scopus]:77  IF:4.0/4.0 | Submit date：2019/01/23