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Uncover the anticancer potential of lycorine Journal article
Zhang, Yan Ming, Li, Ting, Xu, Chun Cao, Qian, Jia Yu, Guo, Hongwei, Zhang, Xiaolei, Zhan, Zha Jun, Lu, Jin Jian. Uncover the anticancer potential of lycorine[J]. Chinese Medicine (United Kingdom), 2024, 19(1), 121.
Authors:  Zhang, Yan Ming;  Li, Ting;  Xu, Chun Cao;  Qian, Jia Yu;  Guo, Hongwei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2024/10/10
Anticancer Mechanism  Lycorine  Lycorine Hydrochloride  Pharmacokinetics  Target  
Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma Journal article
Zhang, Qi Yi, Ding, Wen, Mo, Jian Shan, Ou-yang, Shu Min, Lin, Zi You, Peng, Ke Ren, Liu, Guo Pin, Lu, Jin Jian, Yue, Pei Bin, Lei, Jin Ping, Wang, Yan Dong, Zhang, Xiao Lei. Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma[J]. ACTA PHARMACOLOGICA SINICA, 2024.
Authors:  Zhang, Qi Yi;  Ding, Wen;  Mo, Jian Shan;  Ou-yang, Shu Min;  Lin, Zi You; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:6.9/7.6 | Submit date：2024/05/16
Acquired Sorafenib-resistance  Antisense Oligonucleotide  Hepatocellular Carcinoma  Stat3  
Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1) Journal article
Zhao, Lin, Zhong, Bingling, Zhu, Yanyan, Zheng, Haoyi, Wang, Xumei, Hou, Ying, Lu, Jin Jian, Ai, Nana, Guo, Xiuli, Ge, Wei, Ma, Yan Yan, Chen, Xiuping. Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1)[J]. Biochemical Pharmacology, 2023, 210, 115487.
Authors:  Zhao, Lin;  Zhong, Bingling;  Zhu, Yanyan;  Zheng, Haoyi;  Wang, Xumei; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:5.3/5.2 | Submit date：2023/05/02
Nitrovin  Paraptosis  Trxr1  Ros  Glioblastoma  
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis Journal article
Qing-Xin Ji, Fei-Yan Zeng, Jian Zhou, Wen-Bin Wu, Xu-Jie Wang, Zhen Zhang, Guo-Yan Zhang, Jie Tong, Di-Yang Sun, Jia-Bao Zhang, Wen-Xiang Cao, Fu-Ming Shen, Jin-Jian Lu, Dong-Jie Li, Pei Wang. Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis[J]. Cell Death and Differentiation, 2022, 30(2), 457-474.
Authors:  Qing-Xin Ji;  Fei-Yan Zeng;  Jian Zhou;  Wen-Bin Wu;  Xu-Jie Wang; et al.
Favorite | TC[WOS]:27 TC[Scopus]:26  IF:13.7/13.7 | Submit date：2023/01/30
Oxidative Stress  Apoptosis  Receptor  Growth  Inhibition  Death  Motor  Gpx4  
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Sun, Chong, Zhao, Lin, Wang, Xianzhe, Hou, Ying, Guo, Xiuli, Lu, Jin Jian, Chen, Xiuping. Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells[J]. Journal of Biochemical and Molecular Toxicology, 2022, 36(7), e23051.
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli; et al.
Favorite | TC[WOS]:8 TC[Scopus]:10  IF:3.2/3.3 | Submit date：2022/05/17
Apoptosis  Colon Cancer  Jnk1/2  Chinese Medicine  Psoralidin  Ros  
Garcinone E blocks autophagy through lysosomal functional destruction in ovarian cancer cells Journal article
Xu, Xiao Huang, Chen, Yu Chi, Xu, Yu Lian, Feng, Zhe Ling, Liu, Qian Yu, Guo, Xia, Lin, Li Gen, Lu, Jin Jian. Garcinone E blocks autophagy through lysosomal functional destruction in ovarian cancer cells[J]. World Journal of Traditional Chinese Medicine, 2021, 7(2), 209-216.
Authors:  Xu, Xiao Huang;  Chen, Yu Chi;  Xu, Yu Lian;  Feng, Zhe Ling;  Liu, Qian Yu; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:4.3/0 | Submit date：2021/12/07
Anticancer  Autophagy  Garcinone e  Lysosome  Tfeb  
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Zhang,Le le, Guo,Jing, Jiang,Xiao ming, Chen,Xiu ping, Wang,Yi tao, Li,Ao, Lin,Li gen, Li,Hua, Lu,Jin jian. Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity[J]. Acta Pharmacologica Sinica, 2020, 41(5), 698-705.
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:6.9/7.6 | Submit date：2021/03/01
Nagilactone e  Diterpenoids  Human Lung Cancer A549 Cell Line Xenograft  Rna-seq  Cmap  Click-it  Molecular Docking  Riok2  Protein Synthesis Inhibitor  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Li,Ting, Xu,Xiao Huang, Guo,Xia, Yuan,Tao, Tang,Zheng Hai, Jiang,Xiao Ming, Xu,Yu Lian, Zhang,Le Le, Chen,Xiuping, Zhu,Hong, Shi,Jia Jie, Lu,Jin Jian. Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus[J]. Biochemical Pharmacology, 2020, 175.
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai; et al.
Favorite | TC[WOS]:17 TC[Scopus]:19  IF:5.3/5.2 | Submit date：2021/03/01
Lung Cancer  Notch 3  C-myc  Chop  Apoptosis  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Wen-Xiang Cao, Ting Li, Zheng-Hai Tang, Le-Le Zhang, Zhao-Yu Wang, Xia Guo, Min-Xia Su, Xiuping Chen, Jin-Jian Lu. MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation[J]. Apoptosis, 2018, 23(9-10), 521-531.
Authors:  Wen-Xiang Cao;  Ting Li;  Zheng-Hai Tang;  Le-Le Zhang;  Zhao-Yu Wang; et al.
Favorite | TC[WOS]:13 TC[Scopus]:14 | Submit date：2018/12/28
Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Conference paper
Cao, Wengxiang, Li, Ting, Tang, Zhenghai, Zhang, Lele, Wang, Zhaoyu, Guo, Xia, Su, Minxia, Chen, Xiuping, Lu, Jinjian. MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation[C], 2018.
Authors:  Cao, Wengxiang;  Li, Ting;  Tang, Zhenghai;  Zhang, Lele;  Wang, Zhaoyu; et al.
Favorite |  | Submit date：2023/08/25