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YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment Journal article
Yang, Zhenyun, Wang, Xin, Fu, Yizhen, Wu, Weijie, Hu, Zili, Lin, Qingyang, Peng, Wei, Pan, Yangxun, Wang, Juncheng, Chen, Jinbin, Hu, Dandan, Zhou, Zhongguo, Xu, Li, Zhang, Yaojun, Hou, Jiajie, Chen, Minshan. YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment[J]. Molecular Cancer, 2024, 23(1), 186.
Authors:  Yang, Zhenyun;  Wang, Xin;  Fu, Yizhen;  Wu, Weijie;  Hu, Zili; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:27.7/31.3 | Submit date：2024/10/10
TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response Journal article
Zheng, Mengqi, Zhai, Yunjiao, Yu, Yanbo, Shen, Jing, Chu, Shuzheng, Focaccia, Enrico, Tian, Wenyu, Wang, Sui, Liu, Xuesong, Yuan, Xi, Wang, Yue, Li, Lixiang, Feng, Bingcheng, Li, Zhen, Guo, Xiaohuan, Qiu, Ju, Zhang, Cuijuan, Hou, Jiajie, Sun, Yiyuan, Yang, Xiaoyun, Zuo, Xiuli, Heikenwalder, Mathias, Li, Yanqing, Yuan, Detian, Li, Shiyang. TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response[J]. Cell Metabolism, 2024, 36(9), 2086-2103.
Authors:  Zheng, Mengqi;  Zhai, Yunjiao;  Yu, Yanbo;  Shen, Jing;  Chu, Shuzheng; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:27.7/31.2 | Submit date：2024/08/05
Bile Acid  Detoxification  Infliximab  Tumor Necrosis Factor  Ulcerative Colitis  
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1 Journal article
Duan, Chunyan, Li, Yue, Zhi, Haoyu, Tian, Yao, Huang, Zhengyun, Chen, Suping, Zhang, Yang, Liu, Qing, Zhou, Liang, Jiang, Xiaogang, Ullah, Kifayat, Guo, Qing, Liu, Zhaohui, Xu, Ying, Han, Junhai, Hou, Jiajie, O’Connor, Darran P., Xu, Guo qiang. E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1[J]. ACTA PHARMACOLOGICA SINICA, 2024, 45, 1793-1808.
Authors:  Duan, Chunyan;  Li, Yue;  Zhi, Haoyu;  Tian, Yao;  Huang, Zhengyun; et al.
Favorite | TC[WOS]:2 TC[Scopus]:1  IF:6.9/7.6 | Submit date：2024/06/05
Bmal1  Circadian Rhythm  Proteomics  Transcriptional Activity  Ubiquitination  Ubr5  
Noncanonical Regulation of HOIL-1 on Cancer Stemness and Sorafenib Resistance Identifies Pixantrone as A Novel Therapeutic Agent for Hepatocellular Carcinoma Journal article
Chen, Peng, Dong, Zheyu, Zhu, Wei, Chen, Junling, Zhou, Yuxin, Ye, Qiuyue, Liao, Xinxin, Tan, Yongfa, Li, Chuanjiang, Wang, Yuhao, Pang, Huajin, Wen, Chunhua, Jiang, Yuchuan, Li, Xiaoqing, Li, Bo, Aimaier, Aihetaimu, Lin, Li, Sun, Jian, Hou, Jiajie, Tang, Libo, Hou, Jinlin, Li, Yongyin. Noncanonical Regulation of HOIL-1 on Cancer Stemness and Sorafenib Resistance Identifies Pixantrone as A Novel Therapeutic Agent for Hepatocellular Carcinoma[J]. Hepatology, 2024.
Authors:  Chen, Peng;  Dong, Zheyu;  Zhu, Wei;  Chen, Junling;  Zhou, Yuxin; et al.
Favorite |   IF:12.9/15.5 | Submit date：2023/08/31
Noncanonical regulation of HOIL-1 on cancer stemness and sorafenib resistance identifies pixantrone as a novel therapeutic agent for HCC Journal article
Chen, Peng, Dong, Zheyu, Zhu, Wei, Chen, Junling, Zhou, Yuxin, Ye, Qiuyue, Liao, Xinxin, Tan, Yongfa, Li, Chuanjiang, Wang, Yuhao, Pang, Huajin, Wen, Chunhua, Jiang, Yuchuan, Li, Xiaoqing, Li, Bo, Aimaier, Aihetaimu, Lin, Li, Sun, Jian, Hou, Jiajie, Tang, Libo, Hou, Jinlin, Li, Yongyin. Noncanonical regulation of HOIL-1 on cancer stemness and sorafenib resistance identifies pixantrone as a novel therapeutic agent for HCC[J]. Hepatology, 2024, 80(2), 330-345.
Authors:  Chen, Peng;  Dong, Zheyu;  Zhu, Wei;  Chen, Junling;  Zhou, Yuxin; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:12.9/15.5 | Submit date：2024/08/05
Hepatocellular-carcinoma  Up-regulation  Inhibition  Activation  Growth  Cells  
YTHDF2 upregulation and relocation dictate CD8 T cell polyfunctionality in tumor immunity Presentation
报告日期: 2024-05-01
Authors:  HOU JIAJIE
Favorite |  | Submit date：2024/08/27
Oxygen self-supplying small size magnetic nanoenzymes for synergistic photodynamic and catalytic therapy of breast cancer Journal article
Cai, Xinyi, Xu, Tiantian, Ding, Rui, Zhang, Dou, Chen, Guiquan, Zhao, Wenchang, Hou, Jiajie, Pan, Hong, Zhang, Qian, Yin, Ting. Oxygen self-supplying small size magnetic nanoenzymes for synergistic photodynamic and catalytic therapy of breast cancer[J]. NANOSCALE, 2024, 16(8), 4095-4104.
Authors:  Cai, Xinyi;  Xu, Tiantian;  Ding, Rui;  Zhang, Dou;  Chen, Guiquan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:5.8/6.1 | Submit date：2024/05/16
Correction to: E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1 (Acta Pharmacologica Sinica, (2024), 10.1038/s41401-024-01290-z) Other
2024-01-01
Authors:  Duan, Chun Yan;  Li, Yue;  Zhi, Hao Yu;  Tian, Yao;  Huang, Zheng Yun; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2024/07/04
Acquired TGFβ-NR4A1 signal in tumor-associated γδ T cells confers liver-specific resistance to immune checkpoint blockade Presentation
报告日期: 2023-12-01
Authors:  HOU JIAJIE
Favorite |  | Submit date：2024/08/27
METTL4 limits T cell function in the post-chemotherapeutic tumor microenvironment Project
项目类型: SRG, 项目编号: SRG2023-00005-FHS, 资助机构: UM, 2023-2026
Authors:  HOU JIAJIE
Favorite |  | Submit date：2023/03/29