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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2 Journal article
Duncton M.A.J., Piatnitski Chekler E.L., Katoch-Rouse R., Sherman D., Wong W.C., Smith II L.M., Kawakami J.K., Kiselyov A.S., Milligan D.L., Balagtas C., Hadari Y.R., Wang Y., Patel S.N., Rolster R.L., Tonra J.R., Surguladze D., Mitelman S., Kussie P., Bohlen P., Doody J.F.. Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2[J]. Bioorganic and Medicinal Chemistry, 2009, 17(2), 731-740.
Authors:  Duncton M.A.J.;  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Sherman D.;  Wong W.C.; et al.
Favorite | TC[WOS]:38 TC[Scopus]:38 | Submit date：2019/01/16
Angiogenesis  Arylphthalazine  Inhibitor  Kdr  Kinase  Phthalazine  Vegfr-2  
Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors Journal article
Piatnitski Chekler E.L., Katoch-Rouse R., Kiselyov A.S., Sherman D., Ouyang X., Kim K., Wang Y., Hadari Y.R., Doody J.F.. Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors[J]. Bioorganic and Medicinal Chemistry Letters, 2008, 18(15), 4344-4347.
Authors:  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Kiselyov A.S.;  Sherman D.;  Ouyang X.; et al.
Favorite | TC[WOS]:11 TC[Scopus]:11 | Submit date：2019/01/16
Angiogenesis  Kinase Inhibitor  Vascular Endothelial Growth Factor  
Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non-small cell lung cancers Journal article
Doody J.F., Wang Y., Patel S.N., Joynes C., Sui P.L., Gerlak J., Rolser R.L., Li Y., Steiner P., Bassi R., Hicklin D.J., Hadari Y.R.. Inhibitory activity of cetuximab on epidermal growth factor receptor mutations in non-small cell lung cancers[J]. Molecular Cancer Therapeutics, 2007, 6(10), 2642-2651.
Authors:  Doody J.F.;  Wang Y.;  Patel S.N.;  Joynes C.;  Sui P.L.; et al.
Favorite | TC[WOS]:47 TC[Scopus]:52 | Submit date：2019/01/16
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Smith II L., Wong W.C., Kiselyov A.S., Burdzovic-Wizemann S., Mao Y., Xu Y., Duncton M.A.J., Kim K., Piatnitski E.L., Doody J.F., Wang Y., Rosler R.L., Milligan D., Columbus J., Balagtas C., Lee S.P., Konovalov A., Hadari Y.R.. Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase[J]. Bioorganic and Medicinal Chemistry Letters, 2006, 16(19), 5102-5106.
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.; et al.
Favorite | TC[WOS]:33 TC[Scopus]:38 | Submit date：2019/01/16
Diazepine  Epidermal Growth Factor Receptor  Kinase Inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Smith II L., Piatnitski E.L., Kiselyov A.S., Ouyang X., Chen X., Burdzovic-Wizemann S., Xu Y., Wang Y., Rosler R.L., Patel S.N., Chiang H.-H., Milligan D.L., Columbus J., Wong W.C., Doody J.F., Hadari Y.R.. Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors[J]. Bioorganic and Medicinal Chemistry Letters, 2006, 16(6), 1643-1646.
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:19 | Submit date：2019/01/16
Benzoxazepine  Epidermal Growth Factor Receptor  Kinase Inhibitor  Kinase Selectivity