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Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo Journal article
Shao, Min, Zhao, Chen, Pan, Zhijian, Yang, Xuanjun, Gao, Cheng, Kam, Gloria Hio Cheng, Zhou, Hefeng, Lee, Simon Ming Yuen. Oxyphylla A exerts antiparkinsonian effects by ameliorating 6-OHDA-induced mitochondrial dysfunction and dyskinesia in vitro and in vivo[J]. Chemico-Biological Interactions, 2024, 403, 111224.
Authors:  Shao, Min;  Zhao, Chen;  Pan, Zhijian;  Yang, Xuanjun;  Gao, Cheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.6 | Submit date：2024/10/10
6-ohda  Mitochondria  Neuroprotection  Oxyphylla a  Parkinson's Disease  Target Prediction  
J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice Journal article
Pan, Zhijian, Shao, Min, Zhao, Chen, Yang, Xuanjun, Li, Haitao, Cui, Guozhen, Liang, Xiaonan, Yu, Chao Wu, Ye, Qingqing, Gao, Cheng, Di, Lijun, Chern, Ji Wang, Zhou, Hefeng, Lee, Simon Ming Yuen. J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice[J]. European Journal of Pharmaceutical Sciences, 2024, 194, 106696.
Authors:  Pan, Zhijian;  Shao, Min;  Zhao, Chen;  Yang, Xuanjun;  Li, Haitao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.2 | Submit date：2024/04/02
6-ohda  J24335  Mitochondria Dysfunction  Neurotoxicity  Parkinson's Disease  Target Prediction  
Oral chondroitin sulfate functionalized natural polyphenol for targeted therapy of ulcerative colitis Journal article
Chen, Yi, Shui, Mingju, Yuan, Qin, Li, Hongyi, Zhou, Hefeng, Wang, Yitao, Chen, Zhejie, Wang, Shengpeng. Oral chondroitin sulfate functionalized natural polyphenol for targeted therapy of ulcerative colitis[J]. Materials and Design, 2024, 238, 112645.
Authors:  Chen, Yi;  Shui, Mingju;  Yuan, Qin;  Li, Hongyi;  Zhou, Hefeng; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:7.6/8.4 | Submit date：2024/02/22
Chondroitin Sulfate  Epigallocatechin Gallate  Gut Microbiota  Ros  Ulcerative Colitis  
Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome Journal article
Pan, Zhijian, Yu, Chao Wu, Zhao, Chen, Shao, Min, Yang, Xuanjun, Liang, Xiaonan, Li, Haitao, Lu, Yucong, Ye, Qingqing, Chern, Ji Wang, Lu, Jiahong, Zhou, Hefeng, Lee, Simon Ming Yuen. Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome[J]. Toxicology and Applied Pharmacology, 2023, 480, 116745.
Authors:  Pan, Zhijian;  Yu, Chao Wu;  Zhao, Chen;  Shao, Min;  Yang, Xuanjun; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date：2024/01/02
Immunoproteasome  J24335  Lmp7  Parkinson's Disease  Protein Degradation  Α-synuclein  
Oral Delivery of Transformable Bilirubin Self-Assembled System for Targeted Therapy of Colitis Journal article
Chen,Zhejie, Chen,Yi, Hao,Wei, Shui,Mingju, Zhang,Jinming, Zhou,Hefeng, Zhang,Chen, Wang,Yitao, Wang,Shengpeng. Oral Delivery of Transformable Bilirubin Self-Assembled System for Targeted Therapy of Colitis[J]. Advanced Healthcare Materials, 2023, 12(26), 2300946.
Authors:  Chen,Zhejie;  Chen,Yi;  Hao,Wei;  Shui,Mingju;  Zhang,Jinming; et al.
Favorite | TC[WOS]:7 TC[Scopus]:10  IF:10.0/11.3 | Submit date：2023/08/03
Bilirubin  Chondroitin Sulfate  Intermolecular Hydrogen Bonds  Self-assembled Systems  Ulcerative Colitis  
Ginger polysaccharides relieve ulcerative colitis via maintaining intestinal barrier integrity and gut microbiota modulation Journal article
Hao, Wei, Chen, Zhejie, Yuan, Qin, Ma, Meiling, Gao, Caifang, Zhou, Yangyang, Zhou, Hefeng, Wu, Xu, Wu, Dingtao, Farag, Mohamed A., Wang, Shengpeng, Wang, Yitao. Ginger polysaccharides relieve ulcerative colitis via maintaining intestinal barrier integrity and gut microbiota modulation[J]. International Journal of Biological Macromolecules, 2022, 219, 730-739.
Authors:  Hao, Wei;  Chen, Zhejie;  Yuan, Qin;  Ma, Meiling;  Gao, Caifang; et al.
Favorite | TC[WOS]:28 TC[Scopus]:34  IF:7.7/7.7 | Submit date：2022/11/07
Ginger  Polysaccharides  Ulcerative Colitis  
Targeted delivery of Chinese herb pair-based berberine/tannin acid self-assemblies for the treatment of ulcerative colitis Journal article
Chen, Shiyun, Chen, Zhejie, Wang, Yi, Hao, Wei, Yuan, Qin, Zhou, Hefeng, Gao, Caifang, Wang, Yitao, Wu, Xu, Wang, Shengpeng. Targeted delivery of Chinese herb pair-based berberine/tannin acid self-assemblies for the treatment of ulcerative colitis[J]. Journal of Advanced Research, 2022, 40, 263-276.
Authors:  Chen, Shiyun;  Chen, Zhejie;  Wang, Yi;  Hao, Wei;  Yuan, Qin; et al.
Favorite | TC[WOS]:37 TC[Scopus]:37  IF:11.4/11.0 | Submit date：2022/05/13
Berberine  Drug Delivery  Gut Microbiome  Tannin Acid  Ulcerative Colitis  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Zhou,Hefeng, Li,Shengnan, Li,Chuwen, Yang,Xuanjun, Li,Haitao, Zhong,Hanbing, Lu,Jia Hong, Lee,Simon Ming Yuen. Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome[J]. Aging and Disease, 2020, 11(3), 559-574.
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao; et al.
Favorite | TC[WOS]:13 TC[Scopus]:15  IF:7.0/7.1 | Submit date：2021/03/01
Parkinson's Disease  Α-synuclein  Degradation  Proteasome  Neuroprotection  
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Zhou,Hefeng, Shao,Min, Yang,Xuanjun, Li,Chuwen, Cui,Guozhen, Gao,Cheng, Di,Lijun, Zhong,Hanbing, Wang,Yuqiang, Zhang,Zaijun, Lee,Simon Ming Yuen. Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo[J]. Oxidative Medicine and Cellular Longevity, 2019, 2019.
Authors:  Zhou,Hefeng;  Shao,Min;  Yang,Xuanjun;  Li,Chuwen;  Cui,Guozhen; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:7.310/8.427 | Submit date：2021/03/01
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Zhou,Hefeng, Shao,Min, Guo,Baojian, Li,Chuwen, Lu,Yucong, Yang,Xuanjun, ShengnanLi,, Li,Haitao, Zhu,Qi, Zhong,Hanbing, Wang,Yuqiang, Zhang,Zaijun, Lu,Jiahong, Lee,Simon Ming Yuen. Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models[J]. Neurotherapeutics, 2019, 16(4), 1225-1236.
Authors:  Zhou,Hefeng;  Shao,Min;  Guo,Baojian;  Li,Chuwen;  Lu,Yucong; et al.
Favorite | TC[WOS]:26 TC[Scopus]:28  IF:5.6/6.9 | Submit date：2021/03/01
Degradation  Lmp7  Parkinson’s Disease  Proteasome Activity  Α-synuclein