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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:  Gong, Xiaoqing;  Li, Shuli;  Huang, Junli;  Tan, Shuoyan;  Zhang, Qianqian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.1 | Submit date：2024/10/10
Fingerprint  Lrrk2  Molecular Docking  Pharmacophore  Virtual Screening  Zebrafish  
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications Journal article
Huang, Miaodan, Liu, Yong U., Yao, Xiaoli, Qin, Dajiang, Su, Huanxing. Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications[J]. Translational Neurodegeneration, 2024, 13(1).
Authors:  Huang, Miaodan;  Liu, Yong U.;  Yao, Xiaoli;  Qin, Dajiang;  Su, Huanxing
Favorite | TC[WOS]:1 TC[Scopus]:3  IF:10.8/11.6 | Submit date：2024/09/03
Amyotrophic lateral sclerosis  Genetic therapy  Genotype  Geographic pattern  SOD1 variants  
Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA Journal article
Zhang, Mengjie, Hussain, Abid, Hu, Bo, Yang, Haiyin, Li, Chunhui, Guo, Shuai, Han, Xiaofeng, Li, Bei, Dai, Yunlu, Cao, Yuhong, Chi, Hang, Weng, Yuhua, Qin, Cheng Feng, Huang, Yuanyu. Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA[J]. Nature Communications, 2024, 15(1), 6463.
Authors:  Zhang, Mengjie;  Hussain, Abid;  Hu, Bo;  Yang, Haiyin;  Li, Chunhui; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:14.7/16.1 | Submit date：2024/09/03
Serum Uric-acid  Urate Oxidase  Delivery  Sirna  Risk  Endocytosis  Therapy  
A simple model incorporating foam rheology to quantify foam penetration behaviour in EPB shield tunnelling Journal article
Huang, He, Zhou, Wan Huan, Qin, Su, Bezuijen, Adam. A simple model incorporating foam rheology to quantify foam penetration behaviour in EPB shield tunnelling[J]. Transportation Geotechnics, 2024, 49, 101380.
Authors:  Huang, He;  Zhou, Wan Huan;  Qin, Su;  Bezuijen, Adam
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.9/5.1 | Submit date：2024/10/10
Earth Pressure Balance Shield  Foam Penetration  Laboratory Experiments  Model Simulation  Soil Conditioning  
MHCI trafficking signal-based mRNA vaccines strengthening immune protection against RNA viruses Journal article
Yupei Zhang, Songhui Zhai, Shugang Qin, Yuting Chen, Kepan Chen, Zhiying Huang, Xing Lan, Yaoyao Luo, Guohong Li, Hao Li, Xi He, Meiwan Chen, Zhongwei Zhang, Xingchen Peng, Xin Jiang, Hai Huang, Xiangrong Song. MHCI trafficking signal-based mRNA vaccines strengthening immune protection against RNA viruses[J]. Bioengineering & Translational Medicine, 2024, e10709.
Authors:  Yupei Zhang;  Songhui Zhai;  Shugang Qin;  Yuting Chen;  Kepan Chen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.1/7.2 | Submit date：2024/08/20
Framework  Immune Protection  Mitd  Mrna Vaccines  Rna Virus  
Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency Journal article
Yao, Yuxiao, Jin, Chenchen, Liao, Yilie, Huang, Xiang, Wei, Ziying, Zhang, Yahong, Li, Dongwei, Su, Huanxing, Han, Weiping, Qin, Dajiang. Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency[J]. Aging and Disease, 2024, 15(4), 1952-1968.
Authors:  Yao, Yuxiao;  Jin, Chenchen;  Liao, Yilie;  Huang, Xiang;  Wei, Ziying; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:7.0/7.1 | Submit date：2024/09/03
Hippocampus  Metabolism  Neuron  Prodh  Proline  Schizophrenia  
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications Review article
2024
Authors:  Huang, Miaodan;  Liu, Yong U.;  Yao, Xiaoli;  Qin, Dajiang;  Su, Huanxing
Favorite | TC[WOS]:1 TC[Scopus]:3  IF:10.8/11.6 | Submit date：2024/07/04
Amyotrophic Lateral Sclerosis  Genetic Therapy  Genotype  Geographic Pattern  Sod1 Variants  
Efficient signal sequence of mRNA vaccines enhances the antigen expression to expand the immune protection against viral infection Journal article
Zhang, Yupei, Zhai, Songhui, Huang, Hai, Qin, Shugang, Sun, Min, Chen, Yuting, Lan, Xing, Li, Guohong, Huang, Zhiying, Wang, Denggang, Luo, Yaoyao, Xiao, Wen, Li, Hao, He, Xi, Chen, Meiwan, Peng, Xingchen, Song, Xiangrong. Efficient signal sequence of mRNA vaccines enhances the antigen expression to expand the immune protection against viral infection[J]. Journal of Nanobiotechnology, 2024, 22(1), 295.
Authors:  Zhang, Yupei;  Zhai, Songhui;  Huang, Hai;  Qin, Shugang;  Sun, Min; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:10.6/11.4 | Submit date：2024/07/04
Immune Response  Mrna Vaccines  Signal Sequence  Srp  Virus  
Pressure infiltration behavior and fluid loss of bentonite slurry: a comparative study of two bentonite slurries Journal article
Qin, Su, Cheng, Yang, Huang, He, Zhou, Wan Huan. Pressure infiltration behavior and fluid loss of bentonite slurry: a comparative study of two bentonite slurries[J]. Canadian Geotechnical Journal, 2024, 61(5), 945-958.
Authors:  Qin, Su;  Cheng, Yang;  Huang, He;  Zhou, Wan Huan
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.0/3.9 | Submit date：2024/06/05
Bentonite  Filter Cake  Laboratory Tests  Slurry Infiltration  Tbm Tunnel  
DNA polymerase delta governs parental histone transfer to DNA replication lagging strand Journal article
Tian, Congcong, Zhang, Qin, Jia, Jing, Zhou, Jiaqi, Zhang, Ziwei, Karri, Srinivasu, Jiang, Jiuhang, Dickinson, Quinn, Yao, Yuan, Tang, Xiaorong, Huang, Yuxin, Guo, Ting, He, Ziwei, Liu, Zheng, Gao, Yuan, Yang, Xinran, Wu, Yuchun, Chan, Kui Ming, Zhang, Daoqin, Han, Junhong, Yu, Chuanhe, Gan, Haiyun. DNA polymerase delta governs parental histone transfer to DNA replication lagging strand[J]. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(20), e2400610121.
Authors:  Tian, Congcong;  Zhang, Qin;  Jia, Jing;  Zhou, Jiaqi;  Zhang, Ziwei; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:9.4/10.8 | Submit date：2024/06/05
Dna Polymerase δ  Epigenetic Inheritance  Histone Chaperone  Parental Histone Transfer  Pol32