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Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis Journal article
Head, Sarah A., Shi, Wei Q., Yang, Eun Ju, Nacev, Benjamin A., Hong, Sam Y., Pasunooti, Kalyan K., Li, Ruo-Jing, Shim, Joong Sup, Liu, Jun O.. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis[J]. ACS CHEMICAL BIOLOGY, 2017, 12(1), 174-182.
Authors:  Head, Sarah A.;  Shi, Wei Q.;  Yang, Eun Ju;  Nacev, Benjamin A.;  Hong, Sam Y.; et al.
Favorite | TC[WOS]:65 TC[Scopus]:66  IF:3.5/3.9 | Submit date：2018/10/30
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Sarah A. Head, Wei Shi, Liang Zhao, Kirill Gorshkov, Kalyan Pasunooti, Yue Chen, Zhiyou Deng, Ruo-jing Li, Joong Sup Shim, Wenzhi Tan, Thomas Hartung, Jin Zhang, Yingming Zhao, Marco Colombini, Jun O. Liu. The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112(52), E7276-E7285.
Authors:  Sarah A. Head;  Wei Shi;  Liang Zhao;  Kirill Gorshkov;  Kalyan Pasunooti; et al.
Favorite | TC[WOS]:85 TC[Scopus]:91  IF:9.4/10.8 | Submit date：2019/01/24
Angiogenesis  Mitochondria  Metabolism  Itraconazole  Vdac1