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Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB
Journal article
Linghu, Kegang, Cui, Wenqing, Li, Taiqin, Tuo, Yueting, Wang, Dasong, Pan, Huiqi, Zhang, Tian, Lin, Ligen, Yu, Hua, Hu, Xiaoxia, Li, Haiyang, Shen, Xiangchun. Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB[J]. Acta Pharmaceutica Sinica B, 2024, 14(8), 3561-3575.
Authors:
Linghu, Kegang
;
Cui, Wenqing
;
Li, Taiqin
;
Tuo, Yueting
;
Wang, Dasong
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
4
IF:
14.7
/
14.1
|
Submit date:2024/05/16
A-methylene-g-
Butyrolactone
Rheumatoid Arthritis
Nf-kb P65
Synovial
Microenvironment
Sesquiterpene Lactones
Novel Compound-Target Interactions Prediction for the Herbal Formula Hua-Yu-Qiang-Shen-Tong-Bi-Fang
Journal article
Zihao Wang, Hui-Heng Lin, Kegang Linghu, Run-Yue Huang, Guangyao Li, Huali Zuo, Hua Yu, Ging Chan, Yuanjia Hu. Novel Compound-Target Interactions Prediction for the Herbal Formula Hua-Yu-Qiang-Shen-Tong-Bi-Fang[J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 67(8), 778-785.
Authors:
Zihao Wang
;
Hui-Heng Lin
;
Kegang Linghu
;
Run-Yue Huang
;
Guangyao Li
; et al.
Favorite
|
TC[WOS]:
7
TC[Scopus]:
8
IF:
1.5
/
1.7
|
Submit date:2020/01/06
Herbal Formula
Hua-yu-qiang-shen-tong-bi-fang
Natural Product
In-silico Target Identification
Network Link Prediction
Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells
Journal article
Tingyan Hu, Kegang Linghu, Siqi Huang, Maurizio Battino, Milen I. Georgiev, Gokhan Zengin, Defang Li, Yun Deng, Y.T. Wang, Hui Cao. Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells[J]. Food and Chemical Toxicology, 2019, 127, 188-196.
Authors:
Tingyan Hu
;
Kegang Linghu
;
Siqi Huang
;
Maurizio Battino
;
Milen I. Georgiev
; et al.
Favorite
|
TC[WOS]:
18
TC[Scopus]:
21
IF:
3.9
/
4.5
|
Submit date:2020/03/27
Flaxseed
Mcf-7 cells
Apoptosis
Ros
Mitochondrial Membrane Potential
Dietary Supplement
Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation
Journal article
Sang, Wei, Zhong, Zhangfeng, Linghu, Kegang, Xiong, Wei, Tse, Anfernee Kai Wing, Cheang, Wai San, Yu, Hua, Wang, Yitao. Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation[J]. CHINESE MEDICINE, 2018, 13.
Authors:
Sang, Wei
;
Zhong, Zhangfeng
;
Linghu, Kegang
;
Xiong, Wei
;
Tse, Anfernee Kai Wing
; et al.
Favorite
|
TC[WOS]:
33
TC[Scopus]:
33
IF:
5.3
/
5.5
|
Submit date:2018/10/30
Siegesbeckia Pubescens Makino
Pam(3)Csk(4)
Inflammation
Toll-like Receptor 1/2
Nf-kappa b