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A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway Journal article
Hou, Ying, Zhong, Bingling, Zhao, Lin, Wang, Heng, Zhu, Yanyan, Wang, Xianzhe, Zheng, Haoyi, Yu, Jie, Liu, Guokai, Wang, Xin, Martin-Garcia, Jose M., Chen, Xiuping. A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway[J]. Acta Pharmaceutica Sinica B, 2025.
Authors:  Hou, Ying;  Zhong, Bingling;  Zhao, Lin;  Wang, Heng;  Zhu, Yanyan; et al.
Favorite | TC[Scopus]:0  IF:14.7/14.1 | Submit date：2025/01/22
Calcium  Cancer  Cryptotanshinone  Ferroptosis  Iron  Nad++ Depletion  Nqo1  Targeted Therapy  
The modulation of calcium and chloride channels induces cardiomyocytes from human pluripotent stem cells Journal article
Meng, Ya, Deng, Chunhao, Xiao, Xia, Wei, Shengnan, Song, Chengcheng, Wang, Jiaxian, Lei, Chon Lok, Liu, Weiwei, Chen, Guokai. The modulation of calcium and chloride channels induces cardiomyocytes from human pluripotent stem cells[J]. International Journal of Biological Sciences, 2025, 21(1), 95-108.
Authors:  Meng, Ya;  Deng, Chunhao;  Xiao, Xia;  Wei, Shengnan;  Song, Chengcheng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2025/01/22
Calcium Channel  Cardiomyocyte Derivation  Chloride Channel  Human Pluripotent Stem Cells  Ryanodine Receptor 2  
Medium acidosis drives cardiac differentiation during mesendoderm cell fate specification from human pluripotent stem cells Journal article
Weiwei Liu, Hsun-Ting Hsieh, Ziqing He, Xia Xiao, Chengcheng Song, En Xin Lee, Ji Dong, Chon Lok Lei, Jiaxian Wang, Guokai Chen. Medium acidosis drives cardiac differentiation during mesendoderm cell fate specification from human pluripotent stem cells[J]. Stem Cell Reports, 2024, 19(9), 1304-1319.
Authors:  Weiwei Liu;  Hsun-Ting Hsieh;  Ziqing He;  Xia Xiao;  Chengcheng Song; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:5.9/5.9 | Submit date：2024/08/26
ERK5 promotes autocrine expression to sustain mitogenic balance for cell fate specification in human pluripotent stem cells Journal article
Song, Chengcheng, Zhang, Zhaoying, Leng, Dongliang, He, Ziqing, Wang, Xuepeng, LIU, Weiwei, Zhang, Wensheng, Wu, Qiang, Zhao, Qi, Chen, Guokai. ERK5 promotes autocrine expression to sustain mitogenic balance for cell fate specification in human pluripotent stem cells[J]. Stem Cell Reports, 2024, 19(9), 1320-1335.
Authors:  Song, Chengcheng;  Zhang, Zhaoying;  Leng, Dongliang;  He, Ziqing;  Wang, Xuepeng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.9/5.9 | Submit date：2024/08/27
Carbon Dots Crosslinked Egg White Hydrogel for Tissue Engineering Journal article
Wu, Jun, Lei, Josh Haipeng, Li, Moxin, Zhang, Aiping, Li, Yuan, Liang, Xiao, de Souza, Senio Campos, Yuan, Zhen, Wang, Chunming, Chen, Guokai, Liu, Tzu Ming, Deng, Chu Xia, Tang, Zikang, Qu, Songnan. Carbon Dots Crosslinked Egg White Hydrogel for Tissue Engineering[J]. Advanced Science, 2024, 2404702.
Authors:  Wu, Jun;  Lei, Josh Haipeng;  Li, Moxin;  Zhang, Aiping;  Li, Yuan; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:14.3/16.3 | Submit date：2024/10/10
Carbon Dots  Egg White  Hair Follicle Regeneration  Protein Hydrogels  Wound Healing  
Review immune response of targeting CD39 in cancer Journal article
Yao Liu, Zhongliang Li, Xiaoguang Zhao, Jing Xiao, Jiacheng Bi, Xian-Yang Li, Guokai Chen, Ligong Lu. Review immune response of targeting CD39 in cancer[J]. Biomarker Research, 2023, 11(1).
Authors:  Yao Liu;  Zhongliang Li;  Xiaoguang Zhao;  Jing Xiao;  Jiacheng Bi; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:9.5/9.4 | Submit date：2023/08/03
Adenosine Pathway  Cd39  Immune Checkpoint Blockade (Icb)  Pd-1  
BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells Journal article
Wang, Xuepeng, Song, Chengcheng, Ye, Ying, Gu, Yashi, Li, Xuemei, Chen, Peixin, Leng, Dongliang, Xiao, Jing, Wu, Hao, Xie, Sisi, Liu, Weiwei, Zhao, Qi, Chen, Di, Chen, Xi, Wu, Qiang, Chen, Guokai, Zhang, Wensheng. BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells[J]. Nucleic Acids Research, 2023, 51(21), 11634-11651.
Authors:  Wang, Xuepeng;  Song, Chengcheng;  Ye, Ying;  Gu, Yashi;  Li, Xuemei; et al.
Favorite | TC[WOS]:10 TC[Scopus]:9  IF:16.6/16.1 | Submit date：2024/01/10
Cardiac Differentiation  Pluripotency  Complex  Resistance  Nanog  Brd9  Baf  
Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells Journal article
Yumeng Zhang, Ye Yi, Xia Xiao, Lingling Hu, Jiaqi Xu, Dejin Zheng, Ho Cheng Koc, Un In Chan, Ya Meng, Ligong Lu, Weiwei Liu, Xiaoling Xu, Ningyi Shao, Edwin Chong Wing Cheung, Ren-He Xu, Guokai Chen. Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells[J]. Communications Biology, 2023, 6(1), 476.
Authors:  Yumeng Zhang;  Ye Yi;  Xia Xiao;  Lingling Hu;  Jiaqi Xu; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:5.2/5.6 | Submit date：2023/08/03
Androgen Signaling Contributes to Sex Differences in Cancer by Inhibiting NF-κB Activation in T Cells and Suppressing Antitumor Immunity Journal article
Zhang, Xiaomin, Cheng, Limin, Gao, Chengqi, Chen, Jing, Liao, Shuangye, Zheng, Yongqiang, Xu, Liping, He, Jingjing, Wang, Danyang, Fang, Ziqian, Zhang, Jianeng, Yan, Min, Luan, Yi, Chen, Siyu, Chen, Likun, Xia, Xiaojun, Deng, Chunhao, Chen, Guokai, Li, Wende, Liu, Zexian, Zhou, Penghui. Androgen Signaling Contributes to Sex Differences in Cancer by Inhibiting NF-κB Activation in T Cells and Suppressing Antitumor Immunity[J]. Cancer Research, 2023, 83(6), 906-921.
Authors:  Zhang, Xiaomin;  Cheng, Limin;  Gao, Chengqi;  Chen, Jing;  Liao, Shuangye; et al.
Favorite | TC[WOS]:34 TC[Scopus]:31  IF:12.5/11.6 | Submit date：2023/04/03
Protein Kinase C Modulation Determines the Mesoderm/ Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells Journal article
Godoy-Parejo, Carlos, Deng, Chunhao, Xu, Jiaqi, Zhang, Zhaoying, Ren, Zhili, Ai, Nana, Liu, Weiwei, Ge, Wei, Deng, Chuxia, Xu, Xiaoling, Chin, Y. Eugene, Chen, Guokai. Protein Kinase C Modulation Determines the Mesoderm/ Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells[J]. Stem Cells, 2023, 41(6), 578-591.
Authors:  Godoy-Parejo, Carlos;  Deng, Chunhao;  Xu, Jiaqi;  Zhang, Zhaoying;  Ren, Zhili; et al.
Favorite | TC[WOS]:2 TC[Scopus]:1  IF:4.0/4.9 | Submit date：2023/07/19
Bmp4  Extraembryonic  Fgf  Gf109203x  Human Embryonic Stem Cells  Mesoderm  Protein Kinase c  Signaling Boundary  Trophoblast  Wnt