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Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment Journal article
Zheng, Yanfang, Wang, Chenxiang, Liu, Wenjing, Chen, Jiaying, Sun, Yibin, Chang, Dennis, Wang, Huan, Xu, Wen, Lu, Jin Jian, Zhou, Xian, Huang, Mingqing. Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116579.
Authors:  Zheng, Yanfang;  Wang, Chenxiang;  Liu, Wenjing;  Chen, Jiaying;  Sun, Yibin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/6.8 | Submit date:2024/05/16
Baicalin  Diabetes-associated Cognitive Deficits  Keap1-nrf2  Neuroinflammation  Nlrp3 Inflammasome  Oxidative Stress  
Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma Journal article
Zhang, Qi Yi, Ding, Wen, Mo, Jian Shan, Ou-yang, Shu Min, Lin, Zi You, Peng, Ke Ren, Liu, Guo Pin, Lu, Jin Jian, Yue, Pei Bin, Lei, Jin Ping, Wang, Yan Dong, Zhang, Xiao Lei. Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma[J]. ACTA PHARMACOLOGICA SINICA, 2024.
Authors:  Zhang, Qi Yi;  Ding, Wen;  Mo, Jian Shan;  Ou-yang, Shu Min;  Lin, Zi You; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:6.9/7.6 | Submit date:2024/05/16
Acquired Sorafenib-resistance  Antisense Oligonucleotide  Hepatocellular Carcinoma  Stat3  
Metabolic Reprogramming Driven by IGF2BP3 Promotes Acquired Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer Journal article
Lin,Ziyou, Li,Jingwei, Zhang,Jian, Feng,Weineng, Lu,Jiaye, Ma,Xiaofan, Ding,Wen, Ouyang,Shumin, Lu,Jinjian, Yue,Peibin, Wan,Guohui, Liu,Peiqing, Zhang,Xiaolei. Metabolic Reprogramming Driven by IGF2BP3 Promotes Acquired Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer[J]. Cancer research, 2023, 83(13), 2187-2207.
Authors:  Lin,Ziyou;  Li,Jingwei;  Zhang,Jian;  Feng,Weineng;  Lu,Jiaye; et al.
Favorite | TC[WOS]:32 TC[Scopus]:31  IF:12.5/11.6 | Submit date:2023/08/03
Ophiopogon japonicus and its active compounds: A review of potential anticancer effects and underlying mechanisms Journal article
Liu, Qiao, Lu, Jin-Jian, Hong, Hui-Jie, Yang, Qi, Wang, Yitao, Chen, Xiao-jia. Ophiopogon japonicus and its active compounds: A review of potential anticancer effects and underlying mechanisms[J]. Phytomedicine, 2023, 113, 154718.
Authors:  Liu, Qiao;  Lu, Jin-Jian;  Hong, Hui-Jie;  Yang, Qi;  Wang, Yitao; et al.
Favorite | TC[WOS]:17 TC[Scopus]:20  IF:6.7/6.2 | Submit date:2023/03/22
Ophiopogon Japonicus  Anticancer  Mechanism  Cell Cycle Arrest  Apoptosis  Metastasis  
Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer Journal article
Li,Jingjing, Wang,Yuan, Wang,Li, Hao,Dapeng, Li,Peipei, Su,Minxia, Zhao,Zhiqiang, Liu,Tianyu, Tai,Lixin, Lu,Jinjian, Di,Li Jun. Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer[J]. International journal of biological sciences, 2023, 19(7), 2081-2096.
Authors:  Li,Jingjing;  Wang,Yuan;  Wang,Li;  Hao,Dapeng;  Li,Peipei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:8.2/8.3 | Submit date:2023/08/03
Cisplatin  Ctbp  Drug Resistance  Metformin  Ovarian Cancer  
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo Journal article
Hou, Ying, Liu, Rong, Xia, Mengwei, Sun, Chong, Zhong, Bingling, Yu, Jie, Ai, Nana, Lu, Jin Jian, Ge, Wei, Liu, Bo, Chen, Xiuping. Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo[J]. Pharmacological Research, 2021, 173, 105870.
Authors:  Hou, Ying;  Liu, Rong;  Xia, Mengwei;  Sun, Chong;  Zhong, Bingling; et al.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:9.1/9.0 | Submit date:2021/12/08
Apoptosis  Cyclin D1  G1 Cell Cycle Arrest  Nannocystin Ax  
Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells Journal article
Sun, Chong, Liu, Rong, Xia, Mengwei, Hou, Ying, Wang, Xumei, Lu, Jin jian, Liu, Bo, Chen, Xiuping. Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells[J]. Toxicology and Applied Pharmacology, 2021, 420, 115535.
Authors:  Sun, Chong;  Liu, Rong;  Xia, Mengwei;  Hou, Ying;  Wang, Xumei; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:3.3/3.6 | Submit date:2021/12/08
Emt  Lung Cancer  Metastasis  Nannocystin Ax  
Garcinone E blocks autophagy through lysosomal functional destruction in ovarian cancer cells Journal article
Xu, Xiao Huang, Chen, Yu Chi, Xu, Yu Lian, Feng, Zhe Ling, Liu, Qian Yu, Guo, Xia, Lin, Li Gen, Lu, Jin Jian. Garcinone E blocks autophagy through lysosomal functional destruction in ovarian cancer cells[J]. World Journal of Traditional Chinese Medicine, 2021, 7(2), 209-216.
Authors:  Xu, Xiao Huang;  Chen, Yu Chi;  Xu, Yu Lian;  Feng, Zhe Ling;  Liu, Qian Yu; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:4.3/0 | Submit date:2021/12/07
Anticancer  Autophagy  Garcinone e  Lysosome  Tfeb  
Pien-Tze-Huang attenuates neuroinflammation in cerebral ischaemia-reperfusion injury in rats through the TLR4/NF-κB/MAPK pathway Journal article
Zhang, Xiaoqin, Zhang, Qing, Huang, Lili, Liu, Mingzhen, Cheng, Zaixing, Zheng, Yanfang, Xu, Wen, Lu, Jinjian, Liu, Jian, Huang, Mingqing. Pien-Tze-Huang attenuates neuroinflammation in cerebral ischaemia-reperfusion injury in rats through the TLR4/NF-κB/MAPK pathway[J]. Pharmaceutical Biology, 2021, 59(1), 828-839.
Authors:  Zhang, Xiaoqin;  Zhang, Qing;  Huang, Lili;  Liu, Mingzhen;  Cheng, Zaixing; et al.
Favorite | TC[WOS]:19 TC[Scopus]:24  IF:3.9/4.0 | Submit date:2022/05/13
Ischaemic Stroke  Neuroprotection  Signalling Pathways  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Yao,Nan, Wang,Chen Ran, Liu,Ming Qun, Li,Ying Jie, Chen,Wei Min, Li,Zheng Qiu, Qi,Qi, Lu,Jin Jian, Fan,Chun Lin, Chen,Min Feng, Qi,Ming, Li,Xiao Bo, Hong,Jian, Zhang,Dong Mei, Ye,Wen Cai. Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth[J]. Signal Transduction and Targeted Therapy, 2020, 5(1), 214.
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min; et al.
Favorite | TC[WOS]:28 TC[Scopus]:28  IF:40.8/40.5 | Submit date:2021/03/02