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Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling Journal article
Lu, Changcheng, Huang, Chen, Qu, Shuhui, Lin, Huiyuan, Zhong, Hai Jing, Chong, Cheong Meng. Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling[J]. Biomedicine and Pharmacotherapy, 2024, 173, 116379.
Authors:  Lu, Changcheng;  Huang, Chen;  Qu, Shuhui;  Lin, Huiyuan;  Zhong, Hai Jing; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/05/02
Microglia  Neuroinflammation  Nf-κb P65  Oxyimperatorin  Pro-inflammatory Cytokines  
A comprehensive review of the classical prescription Yiguan Jian: Phytochemistry, quality control, clinical applications, pharmacology, and safety profile Review article
2024
Authors:  Lu, Changcheng;  Zhang, Siyuan;  Lei, Si San;  Wang, Danni;  Peng, Bo; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:4.8/4.8 | Submit date：2023/12/11
Chinese Medicine  Classical Prescription  Clinical Application  Herbal Medicine  Quality Control  Yiguan Jian  
Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells Journal article
Yumeng Zhang, Ye Yi, Xia Xiao, Lingling Hu, Jiaqi Xu, Dejin Zheng, Ho Cheng Koc, Un In Chan, Ya Meng, Ligong Lu, Weiwei Liu, Xiaoling Xu, Ningyi Shao, Edwin Chong Wing Cheung, Ren-He Xu, Guokai Chen. Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells[J]. Communications Biology, 2023, 6(1), 476.
Authors:  Yumeng Zhang;  Ye Yi;  Xia Xiao;  Lingling Hu;  Jiaqi Xu; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:5.2/5.6 | Submit date：2023/08/03
The effects of bioactive components from the rhizome of gastrodia elata blume (Tianma) on the characteristics of Parkinson’s disease Journal article
Lu, Changcheng, Qu, Shuhui, Zhong, Zhangfeng, Luo, Hua, Lei, Si San, Zhong, Hai Jing, Su, Huanxing, Wang, Yitao, Chong, Cheong Meng. The effects of bioactive components from the rhizome of gastrodia elata blume (Tianma) on the characteristics of Parkinson’s disease[J]. Frontiers in Pharmacology, 2022, 13, 963327.
Authors:  Lu, Changcheng;  Qu, Shuhui;  Zhong, Zhangfeng;  Luo, Hua;  Lei, Si San; et al.
Favorite | TC[WOS]:19 TC[Scopus]:20  IF:4.4/5.0 | Submit date：2023/01/30
Dopaminergic Neurons  Neuroinflmamation  Parkisnon’s Disease  Synuclein  Tianma (Gastrodia Elata Blume)  
Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19 Journal article
Yong, Yuan Yuan, Zhang, Li, Hu, Yu Jiao, Wu, Jian Ming, Yan, Lu, Pan, Yi Ru, Tang, Yong, Yu, Lu, Law, Betty Yuen Kwan, Yu, Chong Lin, Zhou, Jie, Li, Mao, Qin, Da Lian, Zhou, Xiao Gang, Wu, An Guo. Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19[J]. Clinical Immunology, 2022, 244.
Authors:  Yong, Yuan Yuan;  Zhang, Li;  Hu, Yu Jiao;  Wu, Jian Ming;  Yan, Lu; et al.
Favorite | TC[WOS]:9 TC[Scopus]:10  IF:4.5/4.7 | Submit date：2023/01/31
Autophagy Regulation  Covid-19  Lung Inflammation  Nlrp3 Inflammasome  Sars-cov-2  
Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway Journal article
Chong, Cheong Meng, Tan, Yuan, Tong, Jiaqi, Ke, Minjing, Zhang, Ke, Yan, Lingli, Cen, Xiaotong, Lu, Jia Hong, Chen, Guobing, Su, Huanxing, Qin, Dajiang. Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway[J]. Cell and Bioscience, 2022, 12(1), 131.
Authors:  Chong, Cheong Meng;  Tan, Yuan;  Tong, Jiaqi;  Ke, Minjing;  Zhang, Ke; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.1/7.0 | Submit date：2023/01/30
Mtor  Presenilin-1  Ipsc  Crispr/cas9  
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease Journal article
Zhou, Xiao Gang, Qiu, Wen Qiao, Yu, Lu, Pan, Rong, Teng, Jin Feng, Sang, Zhi Pei, Law, Betty Yuen Kwan, Zhao, Ya, Zhang, Li, Yan, Lu, Tang, Yong, Sun, Xiao Lei, Wong, Vincent Kam Wai, Yu, Chong Lin, Wu, Jian Ming, Qin, Da Lian, Wu, An Guo. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease[J]. Inflammation and Regeneration, 2022, 42(1).
Authors:  Zhou, Xiao Gang;  Qiu, Wen Qiao;  Yu, Lu;  Pan, Rong;  Teng, Jin Feng; et al.
Favorite | TC[WOS]:23 TC[Scopus]:23  IF:5.0/7.2 | Submit date：2023/01/30
Alzheimer’s Disease  Ampk/ulk1  Autophagy  Nlrp3 Inflammasome  Raf/mek/erk  Thonningianin a  
Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals Journal article
Wu, An Guo, Yong, Yuan Yuan, Pan, Yi Ru, Zhang, Li, Wu, Jian Ming, Zhang, Yue, Tang, Yong, Wei, Jing, Yu, Lu, Law, Betty Yuen Kwan, Yu, Chong Lin, Liu, Jian, Lan, Cai, Xu, Ru Xiang, Zhou, Xiao Gang, Qin, Da Lian. Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals[J]. Oxidative Medicine and Cellular Longevity, 2022, 2022.
Authors:  Wu, An Guo;  Yong, Yuan Yuan;  Pan, Yi Ru;  Zhang, Li;  Wu, Jian Ming; et al.
Favorite | TC[WOS]:45 TC[Scopus]:45  IF:7.310/8.427 | Submit date：2023/01/30
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Sun, Chong, Zhao, Lin, Wang, Xianzhe, Hou, Ying, Guo, Xiuli, Lu, Jin Jian, Chen, Xiuping. Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells[J]. Journal of Biochemical and Molecular Toxicology, 2022, 36(7), e23051.
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli; et al.
Favorite | TC[WOS]:8 TC[Scopus]:10  IF:3.2/3.3 | Submit date：2022/05/17
Apoptosis  Colon Cancer  Jnk1/2  Chinese Medicine  Psoralidin  Ros  
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy Journal article
Qiu, Wen Qiao, Ai, Wei, Zhu, Feng Dan, Zhang, Yue, Guo, Min Song, Law, Betty Yuen Kwan, Wu, Jian Ming, Wong, Vincent Kam Wai, Tang, Yong, Yu, Lu, Chen, Qi, Yu, Chong Lin, Liu, Jian, Qin, Da Lian, Zhou, Xiao Gang, Wu, An Guo. Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy[J]. Free Radical Biology and Medicine, 2022, 179, 76-94.
Authors:  Qiu, Wen Qiao;  Ai, Wei;  Zhu, Feng Dan;  Zhang, Yue;  Guo, Min Song; et al.
Favorite | TC[WOS]:44 TC[Scopus]:48  IF:7.1/7.9 | Submit date：2023/01/30
Mitophagy  Neurodegenerative Disease  Nlrp3 Inflammasome  Polygala Saponins  Radix Polygalae  Shp-2