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Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Botkjaer K.A., Kwok H.F., Terp M.G., Karatt-Vellatt A., Santamaria S., McCafferty J., Andreasen P.A., Itoh Y., Ditzel H.J., Murphy G.. Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo[J]. Oncotarget, 2016, 7(13), 16773-16792.
Authors:  Botkjaer K.A.;  Kwok H.F.;  Terp M.G.;  Karatt-Vellatt A.;  Santamaria S.; et al.
Favorite | TC[WOS]:33 TC[Scopus]:34 | Submit date：2018/12/19
Antibody  In Vivo targetIng  Metastasis  Mt1-mmp  Non-catalytic Sites  
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Botkjaer, K.A., Kwok, H. F., Terp, M.G., Karatt-Vellatt, A., Santamaria, S., McCafferty, J., Andreasen, P.A., Itoh, Y., Ditzel, H.J., Murphy, G.. Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo[J]. Oncotarget, 2016, 1-20.
Authors:  Botkjaer, K.A.;  Kwok, H. F.;  Terp, M.G.;  Karatt-Vellatt, A.;  Santamaria, S.; et al.
Favorite |   IF:5.168/5.312 | Submit date：2022/06/02
MT1-MMP  antibody  non-catalytic sites  in vivo targeting  metastasis  
Discovery and Development of Therapeutic TACE (ADAM17) Antibodies Conference paper
Kwok, H. F., Botkjaer, K., Tape, C., Huang, Y., McCafferty, J., Murphy, G.. Discovery and Development of Therapeutic TACE (ADAM17) Antibodies[C], 2015.
Authors:  Kwok, H. F.;  Botkjaer, K.;  Tape, C.;  Huang, Y.;  McCafferty, J.; et al.
Favorite |  | Submit date：2022/06/02
Cross-Reactive  Anti-TACE Antibody  Mouse Models  
Development of a ‘mouse and human cross-reactive’ affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy Journal article
Kwok, H. F., Botkjaer, K. A., Tape, C. J., Huang, Y., McCafferty, J., Murphy, G.. Development of a ‘mouse and human cross-reactive’ affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy[J]. Protein engineering, design & selection : PEDS Oxford University Press, 2014, 179-190.
Authors:  Kwok, H. F.;  Botkjaer, K. A.;  Tape, C. J.;  Huang, Y.;  McCafferty, J.; et al.
Favorite |   IF:2.6/2.0 | Submit date：2022/06/02
anti-TACE antibody  exosite  immunoreactivity  phage-display randomization libraries  sub-nanomolar affinity  
Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy Journal article
Kwok H.F., Botkjaer K.A., Tape C.J., Huang Y., McCafferty J., Murphy G.. Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy[J]. Protein engineering, design & selection : PEDS Oxford University Press, 2014, 27(6), 179-190.
Authors:  Kwok H.F.;  Botkjaer K.A.;  Tape C.J.;  Huang Y.;  McCafferty J.; et al.
Favorite | TC[WOS]:29 TC[Scopus]:30 | Submit date：2018/12/19
Anti-tace Antibody  Exosite  Immunoreactivity  Phage-display Randomization Libraries  Sub-nanomolar Affinity