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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2 Journal article
Duncton M.A.J., Piatnitski Chekler E.L., Katoch-Rouse R., Sherman D., Wong W.C., Smith II L.M., Kawakami J.K., Kiselyov A.S., Milligan D.L., Balagtas C., Hadari Y.R., Wang Y., Patel S.N., Rolster R.L., Tonra J.R., Surguladze D., Mitelman S., Kussie P., Bohlen P., Doody J.F.. Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2[J]. Bioorganic and Medicinal Chemistry, 2009, 17(2), 731-740.
Authors:  Duncton M.A.J.;  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Sherman D.;  Wong W.C.; et al.
Favorite | TC[WOS]:38 TC[Scopus]:38 | Submit date：2019/01/16
Angiogenesis  Arylphthalazine  Inhibitor  Kdr  Kinase  Phthalazine  Vegfr-2  
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Smith II L., Wong W.C., Kiselyov A.S., Burdzovic-Wizemann S., Mao Y., Xu Y., Duncton M.A.J., Kim K., Piatnitski E.L., Doody J.F., Wang Y., Rosler R.L., Milligan D., Columbus J., Balagtas C., Lee S.P., Konovalov A., Hadari Y.R.. Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase[J]. Bioorganic and Medicinal Chemistry Letters, 2006, 16(19), 5102-5106.
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.; et al.
Favorite | TC[WOS]:33 TC[Scopus]:38 | Submit date：2019/01/16
Diazepine  Epidermal Growth Factor Receptor  Kinase Inhibitor  Oxazepine  Thiazepine  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Ouyang X., Chen X., Piatnitski E.L., Kiselyov A.S., He H.-Y., Mao Y., Pattaropong V., Yu Y., Kim K.H., Kincaid J., Smith II L., Wong W.C., Lee S.P., Milligan D.L., Malikzay A., Fleming J., Gerlak J., Deevi D., Doody J.F., Chiang H.-H., Patel S.N., Wang Y., Rolser R.L., Kussie P., Labelle M., Tuma M.C.. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors[J]. Bioorganic and Medicinal Chemistry Letters, 2005, 15(23), 5154-5159.
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.; et al.
Favorite | TC[WOS]:66 TC[Scopus]:70 | Submit date：2019/01/16
1,2,4-triazole  Antimitotic  Tubulin Inhibitor  Tubulin Polymerization  Tumor Vasculature  Vascular Disrupting Agent