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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation
Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:
Gong, Xiaoqing
;
Li, Shuli
;
Huang, Junli
;
Tan, Shuoyan
;
Zhang, Qianqian
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
6.0
/
6.1
|
Submit date:2024/10/10
Fingerprint
Lrrk2
Molecular Docking
Pharmacophore
Virtual Screening
Zebrafish
Exploration and validation of ceRNA regulatory networks in colorectal cancer based on associations whole transcriptome sequencing
Journal article
Zhang, Lulu, Li, Yulei, Fu, Chao, Yang, Li Xia, Li, Gang, Wu, Yiyang, Tong, Huanjun, Tian, Guojiang, Wang, Kaifang, Wang, Jun, Ying, Xiaojiang, Li, Zhenjun. Exploration and validation of ceRNA regulatory networks in colorectal cancer based on associations whole transcriptome sequencing[J]. Scientific Reports, 2024, 14(1), 20446.
Authors:
Zhang, Lulu
;
Li, Yulei
;
Fu, Chao
;
Yang, Li Xia
;
Li, Gang
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
3.8
/
4.3
|
Submit date:2024/10/10
Competing Endogenous Rna
Crc
Expression Pattern
Non-coding Rna
Whole Transcriptome
Characterization of deglycosylated metabolites of platycosides reveals their biotransformation after oral administration
Journal article
Yau, Lee Fong, Huang, Hao, Tong, Tian Tian, Bai, Long Bo, Zhu, Guo Yuan, Hou, Yuanyuan, Bai, Gang, Jiang, Zhi Hong. Characterization of deglycosylated metabolites of platycosides reveals their biotransformation after oral administration[J]. Food Chemistry, 2022, 393.
Authors:
Yau, Lee Fong
;
Huang, Hao
;
Tong, Tian Tian
;
Bai, Long Bo
;
Zhu, Guo Yuan
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
3
IF:
8.5
/
8.2
|
Submit date:2023/01/31
3-o-β-d-glucopyranosyl Platycosides
Alkaline Hydrolysis
Deglycosylated Metabolites
Functional Foods
Platycodon Grandiflorus
Improvement of tissue-specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol
Journal article
Bai, Long Bo, Yau, Lee Fong, Tong, Tian Tian, Chan, Wai Him, Zhang, Wei, Jiang, Zhi Hong. Improvement of tissue-specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol[J]. Pharmacology Research and Perspectives, 2022, 10(4).
Authors:
Bai, Long Bo
;
Yau, Lee Fong
;
Tong, Tian Tian
;
Chan, Wai Him
;
Zhang, Wei
; et al.
Favorite
|
TC[WOS]:
6
TC[Scopus]:
6
IF:
2.9
/
2.9
|
Submit date:2023/01/30
Combination Therapy
Ginsenosides
Lc-mrm
Nad++
Nmn
Resveratrol
Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3
Journal article
Li, Dan, Yang, Chao, Zhu, Jian zhong, Lopez, Eduardo, Zhang, Tian, Tong, Qiang, Peng, Cheng, Lin, Li gen. Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3[J]. ACTA PHARMACOLOGICA SINICA, 2022, 43(5), 1285-1298.
Authors:
Li, Dan
;
Yang, Chao
;
Zhu, Jian zhong
;
Lopez, Eduardo
;
Zhang, Tian
; et al.
Favorite
|
TC[WOS]:
38
TC[Scopus]:
42
IF:
6.9
/
7.6
|
Submit date:2022/05/13
Adipose Tissue Inflammation
Berberine
Fibrosis
Insulin Resistance
Liver Injury
Sirtuin 3
Glycomic Analysis Reveals That Sialyltransferase Inhibition Is Involved in the Antiviral Effects of Arbidol
Journal article
Kang, Yue, Mai, Zhi Tong, Yau, Lee Fong, Li, Run Feng, Tong, Tian Tian, Yang, Chun Guang, Chan, Ka Man, Jiang, Zhi Hong, Wang, Yutao, Yang, Zi Feng, Wang, Jing Rong. Glycomic Analysis Reveals That Sialyltransferase Inhibition Is Involved in the Antiviral Effects of Arbidol[J]. Journal of Virology, 2022, 96(6).
Authors:
Kang, Yue
;
Mai, Zhi Tong
;
Yau, Lee Fong
;
Li, Run Feng
;
Tong, Tian Tian
; et al.
Favorite
|
TC[WOS]:
3
TC[Scopus]:
3
IF:
4.0
/
4.0
|
Submit date:2023/01/30
Arbidol
Glycomic
Influenza Virus
Sialic Acid Receptor
Sialyltransferase
A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer
Journal article
Li,Guodong, Henry,Stuart Adam, Liu,Hao, Kang,Tian Shu, Nao,Sang Cuo, Zhao,Yichao, Wu,Chun, Jin,Jianwen, Zhang,Jia Tong, Leung,Chung Hang, Wai Hong Chan,Philip, Ma,Dik Lung. A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer[J]. Chemical Science, 2020, 11(7), 1750-1760.
Authors:
Li,Guodong
;
Henry,Stuart Adam
;
Liu,Hao
;
Kang,Tian Shu
;
Nao,Sang Cuo
; et al.
Favorite
|
TC[WOS]:
29
TC[Scopus]:
31
IF:
7.6
/
8.0
|
Submit date:2021/03/01
SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK
Journal article
Zhang,Tian, Liu,Jingxin, Tong,Qiang, Lin,Ligen. SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK[J]. International Journal of Molecular Sciences, 2020, 21(2), 372.
Authors:
Zhang,Tian
;
Liu,Jingxin
;
Tong,Qiang
;
Lin,Ligen
Favorite
|
TC[WOS]:
50
TC[Scopus]:
50
IF:
4.9
/
5.6
|
Submit date:2021/03/01
Ampk
Chaperone-mediated Autophagy
Lipid Metabolism
Macroautophagy
Sirtuin 3
Polyunsaturated fatty acids from microalgae Spirulina platensis modulates lipid metabolism disorders and gut microbiota in high-fat diet rats
Journal article
Li, Tian Tian, Tong, Ai Jun, Liu, Yuan Yuan, Huang, Zi Rui, Wan, Xu Zhi, Pan, Yu Yang, Jia, Rui Bo, Liu, Bin, Chen, Xin Hua, Zhao, Chao. Polyunsaturated fatty acids from microalgae Spirulina platensis modulates lipid metabolism disorders and gut microbiota in high-fat diet rats[J]. Food and Chemical Toxicology, 2019, 131.
Authors:
Li, Tian Tian
;
Tong, Ai Jun
;
Liu, Yuan Yuan
;
Huang, Zi Rui
;
Wan, Xu Zhi
; et al.
Favorite
|
TC[WOS]:
62
TC[Scopus]:
64
IF:
3.9
/
4.5
|
Submit date:2022/05/17
Gut Microbiota
Hyperlipidaemia
Polyunsaturated Fatty Acids
Signal Pathway
Spirulina Platensis
Enhancing the Efficiency and Stability of NiOx-Based Silicon Photoanode via Interfacial Engineering
Journal article
Zhiqin Ying, Xi Yang, Rui Tong, Qing Zhu, Tian Chen, Zhubing He, Hui Pan. Enhancing the Efficiency and Stability of NiOx-Based Silicon Photoanode via Interfacial Engineering[J]. ACS Applied Energy Materials, 2019, 2(9), 6883-6890.
Authors:
Zhiqin Ying
;
Xi Yang
;
Rui Tong
;
Qing Zhu
;
Tian Chen
; et al.
Favorite
|
TC[WOS]:
8
TC[Scopus]:
9
IF:
5.4
/
5.9
|
Submit date:2021/03/09
Au Nanoparticles
Niox
Photoelectrochemical Water-splitting
Pinch-off Effect
Silicon Photoanode