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Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment Journal article
Zheng, Yanfang, Wang, Chenxiang, Liu, Wenjing, Chen, Jiaying, Sun, Yibin, Chang, Dennis, Wang, Huan, Xu, Wen, Lu, Jin Jian, Zhou, Xian, Huang, Mingqing. Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116579.
Authors:  Zheng, Yanfang;  Wang, Chenxiang;  Liu, Wenjing;  Chen, Jiaying;  Sun, Yibin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/6.8 | Submit date：2024/05/16
Baicalin  Diabetes-associated Cognitive Deficits  Keap1-nrf2  Neuroinflammation  Nlrp3 Inflammasome  Oxidative Stress  
Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma Journal article
Zhang, Qi Yi, Ding, Wen, Mo, Jian Shan, Ou-yang, Shu Min, Lin, Zi You, Peng, Ke Ren, Liu, Guo Pin, Lu, Jin Jian, Yue, Pei Bin, Lei, Jin Ping, Wang, Yan Dong, Zhang, Xiao Lei. Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma[J]. ACTA PHARMACOLOGICA SINICA, 2024.
Authors:  Zhang, Qi Yi;  Ding, Wen;  Mo, Jian Shan;  Ou-yang, Shu Min;  Lin, Zi You; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:6.9/7.6 | Submit date：2024/05/16
Acquired Sorafenib-resistance  Antisense Oligonucleotide  Hepatocellular Carcinoma  Stat3  
Paraptosis: a non-classical paradigm of cell death for cancer therapy Review article
2024
Authors:  Xu, Chun cao;  Lin, Yi fan;  Huang, Mu yang;  Zhang, Xiao lei;  Wang, Pei; et al.
Favorite | TC[WOS]:20 TC[Scopus]:17  IF:6.9/7.6 | Submit date：2024/02/22
Cancer Therapy  Endoplasmic Reticulum  Er Stress  Mitochondria  Paraptosis  
Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia Journal article
Mo, Jianshan, Deng, Lin, Peng, Keren, Ouyang, Shumin, Ding, Wen, Lou, Linlin, Lin, Ziyou, Zhu, Jianzheng, Li, Jingwei, Zhang, Qiyi, Wang, Pengyan, Wen, Yuanzhen, Chen, Xiaobing, Yue, Peibin, Lu, Jin Jian, Zhu, Kai, Zheng, Yongjiang, Wang, Yuanxiang, Zhang, Xiaolei. Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia[J]. Journal of Hematology & Oncology, 2023, 16(1), 15.
Authors:  Mo, Jianshan;  Deng, Lin;  Peng, Keren;  Ouyang, Shumin;  Ding, Wen; et al.
Favorite | TC[WOS]:15 TC[Scopus]:14  IF:29.5/26.9 | Submit date：2023/03/06
Aml  Immunotherapy  Stat3 Inhibitor  Vista  
Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer Journal article
Wang, Xianzhe, Shi, Wei, Wang, Xumei, Lu, Jin Jian, He, Ping, Zhang, Hongjie, Chen, Xiuping. Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer[J]. Cell Death Discovery, 2023, 9(1), 355.
Authors:  Wang, Xianzhe;  Shi, Wei;  Wang, Xumei;  Lu, Jin Jian;  He, Ping; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.1/6.0 | Submit date：2024/01/02
Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1) Journal article
Zhao, Lin, Zhong, Bingling, Zhu, Yanyan, Zheng, Haoyi, Wang, Xumei, Hou, Ying, Lu, Jin Jian, Ai, Nana, Guo, Xiuli, Ge, Wei, Ma, Yan Yan, Chen, Xiuping. Nitrovin (difurazone), an antibacterial growth promoter, induces ROS-mediated paraptosis-like cell death by targeting thioredoxin reductase 1 (TrxR1)[J]. Biochemical Pharmacology, 2023, 210, 115487.
Authors:  Zhao, Lin;  Zhong, Bingling;  Zhu, Yanyan;  Zheng, Haoyi;  Wang, Xumei; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:5.3/5.2 | Submit date：2023/05/02
Nitrovin  Paraptosis  Trxr1  Ros  Glioblastoma  
Ophiopogon japonicus and its active compounds: A review of potential anticancer effects and underlying mechanisms Journal article
Liu, Qiao, Lu, Jin-Jian, Hong, Hui-Jie, Yang, Qi, Wang, Yitao, Chen, Xiao-jia. Ophiopogon japonicus and its active compounds: A review of potential anticancer effects and underlying mechanisms[J]. Phytomedicine, 2023, 113, 154718.
Authors:  Liu, Qiao;  Lu, Jin-Jian;  Hong, Hui-Jie;  Yang, Qi;  Wang, Yitao; et al.
Favorite | TC[WOS]:16 TC[Scopus]:19  IF:6.7/6.2 | Submit date：2023/03/22
Ophiopogon Japonicus  Anticancer  Mechanism  Cell Cycle Arrest  Apoptosis  Metastasis  
Comparison of Ophiopogon japonicus and Liriope spicata var. prolifera from Different Origins Based on Multi-Component Quantification and Anticancer Activity Journal article
Chen, Min-Hui, Leong, Fong, Gao, Si-Jia, Chen, Xin, Lu, Jin-Jian, Lin, Li-Gen, Wang, Yitao, Chen, Xiao-jia. Comparison of Ophiopogon japonicus and Liriope spicata var. prolifera from Different Origins Based on Multi-Component Quantification and Anticancer Activity[J]. Molecules, 2023, 28(3), 1045.
Authors:  Chen, Min-Hui;  Leong, Fong;  Gao, Si-Jia;  Chen, Xin;  Lu, Jin-Jian; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.2/4.6 | Submit date：2023/02/01
Ophiopogon Japonicus  Liriope Spicata Var. Prolifera  Hplc-dad-elsd  Anticancer  Steroidal Saponins  Homoisoflavonoids  
Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer Journal article
Li,Jingjing, Wang,Yuan, Wang,Li, Hao,Dapeng, Li,Peipei, Su,Minxia, Zhao,Zhiqiang, Liu,Tianyu, Tai,Lixin, Lu,Jinjian, Di,Li Jun. Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer[J]. International journal of biological sciences, 2023, 19(7), 2081-2096.
Authors:  Li,Jingjing;  Wang,Yuan;  Wang,Li;  Hao,Dapeng;  Li,Peipei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:8.2/8.3 | Submit date：2023/08/03
Cisplatin  Ctbp  Drug Resistance  Metformin  Ovarian Cancer  
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis Journal article
Qing-Xin Ji, Fei-Yan Zeng, Jian Zhou, Wen-Bin Wu, Xu-Jie Wang, Zhen Zhang, Guo-Yan Zhang, Jie Tong, Di-Yang Sun, Jia-Bao Zhang, Wen-Xiang Cao, Fu-Ming Shen, Jin-Jian Lu, Dong-Jie Li, Pei Wang. Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis[J]. Cell Death and Differentiation, 2022, 30(2), 457-474.
Authors:  Qing-Xin Ji;  Fei-Yan Zeng;  Jian Zhou;  Wen-Bin Wu;  Xu-Jie Wang; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26  IF:13.7/13.7 | Submit date：2023/01/30
Oxidative Stress  Apoptosis  Receptor  Growth  Inhibition  Death  Motor  Gpx4