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Characterization of a polysaccharide from Amauroderma rugosum and its proangiogenic activities in vitro and in vivo Journal article
Nie, Xin, Li, Jingjing, Cheng, Yanfen, Rangsinth, Panthakarn, Wu, Xiaoping, Zheng, Chengwen, Shiu, Polly Ho Ting, Li, Renkai, Xu, Nan, He, Yulin, Lau, Benson Wui Man, Seto, Sai Wang, Zhang, Jinming, Lee, Simon Ming Yuen, Leung, George Pak Heng. Characterization of a polysaccharide from Amauroderma rugosum and its proangiogenic activities in vitro and in vivo[J]. International Journal of Biological Macromolecules, 2024, 271, 132533.
Authors:  Nie, Xin;  Li, Jingjing;  Cheng, Yanfen;  Rangsinth, Panthakarn;  Wu, Xiaoping; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:7.7/7.7 | Submit date：2024/06/05
Amauroderma Rugosum  Polysaccharides  Proangiogenesis  
A new invertebrate NPY-like polypeptide, ZoaNPY, from the Zoanthus sociatus, as a novel ligand of human NPY Y2 receptor rescues vascular insufficiency via PLC/PKC and Src- FAK-dependent signaling pathways Journal article
Chen, Qian, Xu, Nan, Zhao, Chen, He, Yulin, Kam, Sandy Hio Tong, Wu, Xue, Huang, Pan, Yang, Min, Wong, Clarence Tsun Ting, Radis-Baptista, Gandhi, Tang, Benqin, Fan, Guangyi, Gong, Guiyi, Lee, Simon Ming Yuen. A new invertebrate NPY-like polypeptide, ZoaNPY, from the Zoanthus sociatus, as a novel ligand of human NPY Y2 receptor rescues vascular insufficiency via PLC/PKC and Src- FAK-dependent signaling pathways[J]. Pharmacological Research, 2024, 203, 107173.
Authors:  Chen, Qian;  Xu, Nan;  Zhao, Chen;  He, Yulin;  Kam, Sandy Hio Tong; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:9.1/9.0 | Submit date：2024/05/16
Angiogenesis  Cnidarian  Invertebrate Neuropeptide y  Npy Y2r  Transcriptome  
J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice Journal article
Pan, Zhijian, Shao, Min, Zhao, Chen, Yang, Xuanjun, Li, Haitao, Cui, Guozhen, Liang, Xiaonan, Yu, Chao Wu, Ye, Qingqing, Gao, Cheng, Di, Lijun, Chern, Ji Wang, Zhou, Hefeng, Lee, Simon Ming Yuen. J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice[J]. European Journal of Pharmaceutical Sciences, 2024, 194, 106696.
Authors:  Pan, Zhijian;  Shao, Min;  Zhao, Chen;  Yang, Xuanjun;  Li, Haitao; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.2 | Submit date：2024/04/02
6-ohda  J24335  Mitochondria Dysfunction  Neurotoxicity  Parkinson's Disease  Target Prediction  
A Systematic Review of the Design of Serious Games for Innovative Learning: Augmented Reality, Virtual Reality, or Mixed Reality? Review article
2024
Authors:  Lee, Lap Kei;  Wei, Xiaodong;  Chui, Kwok Tai;  Cheung, Simon K.S.;  Wang, Fu Lee; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:2.6/2.6 | Submit date：2024/05/16
Augmented Reality  Blended Learning  E-learning  Hybrid Learning  Immersive Learning  Innovative Learning  Mixed Reality  Serious Games  Smart Education  Virtual Reality  
Structure and activity relationship analysis of xanthones from mangosteen: Identifying garcinone E as a potent dual EGFR and VEGFR2 inhibitor Journal article
Li, Jingjing, Nie, Xin, Panthakarn Rangsinth,, Wu, Xiaoping, Zheng, Chengwen, Cheng, Yanfen, Shiu, Polly Ho Ting, Li, Renkai, Lee, Simon Ming Yuen, Fu, Chaomei, Zhang, Jinming, Leung, George Pak Heng. Structure and activity relationship analysis of xanthones from mangosteen: Identifying garcinone E as a potent dual EGFR and VEGFR2 inhibitor[J]. Phytomedicine, 2024, 122, 155140.
Authors:  Li, Jingjing;  Nie, Xin;  Panthakarn Rangsinth,;  Wu, Xiaoping;  Zheng, Chengwen; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:6.7/6.2 | Submit date：2024/02/22
Epidermal Growth Factor Receptor  Garcinone e  Mangosteen  Vascular Endothelial Growth Factor Receptor 2  Xanthones  
Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome Journal article
Pan, Zhijian, Yu, Chao Wu, Zhao, Chen, Shao, Min, Yang, Xuanjun, Liang, Xiaonan, Li, Haitao, Lu, Yucong, Ye, Qingqing, Chern, Ji Wang, Lu, Jiahong, Zhou, Hefeng, Lee, Simon Ming Yuen. Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome[J]. Toxicology and Applied Pharmacology, 2023, 480, 116745.
Authors:  Pan, Zhijian;  Yu, Chao Wu;  Zhao, Chen;  Shao, Min;  Yang, Xuanjun; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.3/3.6 | Submit date：2024/01/02
Immunoproteasome  J24335  Lmp7  Parkinson's Disease  Protein Degradation  Α-synuclein  
6-benzylaminopurine causes endothelial dysfunctions to human umbilical vein endothelial cells and exacerbates atorvastatin-induced cerebral hemorrhage in zebrafish Journal article
Gong, Guiyi, Kam, Hiotong, Bai, Yubin, Cheang, Wai San, Wu, Shuilong, Cheng, Xiaoning, Giesy, John P., Lee, Simon Ming-yuen. 6-benzylaminopurine causes endothelial dysfunctions to human umbilical vein endothelial cells and exacerbates atorvastatin-induced cerebral hemorrhage in zebrafish[J]. Environmental Toxicology, 2023, 39(3), 1258-1268.
Authors:  Gong, Guiyi;  Kam, Hiotong;  Bai, Yubin;  Cheang, Wai San;  Wu, Shuilong; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.4/4.2 | Submit date：2023/11/07
6-benzylaminopurine  Huvecs  Mapk Pathway  Cerebral Hemorrhage  Endothelial Toxicity  
Carrier-Free Gambogic Acid Dimer Self-Assembly Nanomedicines for Rheumatoid Arthritis Treatment Journal article
Liu, Yuling, Nie, Xin, Wu, Yihan, Lin, Longfei, Liao, Qian, Li, Jingjing, Lee, Simon Ming Yuen, Li, Hui, Zhang, Jinming. Carrier-Free Gambogic Acid Dimer Self-Assembly Nanomedicines for Rheumatoid Arthritis Treatment[J]. International Journal of Nanomedicine, 2023, 18, 5457-5472.
Authors:  Liu, Yuling;  Nie, Xin;  Wu, Yihan;  Lin, Longfei;  Liao, Qian; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4 | Submit date：2024/02/22
Carrier-free Nanoparticles  Gambogic Acid Dimers  Macrophage  Osteoclast  Rheumatoid Arthritis  Self-assembly  
Dual effect of aucubin on promoting VEGFR2 mediated angiogenesis and reducing RANKL-induced bone resorption Journal article
He, Yulin, Kam, Hiotong, Wu, Xue, Chen, Qian, Lee, Simon Ming Yuen. Dual effect of aucubin on promoting VEGFR2 mediated angiogenesis and reducing RANKL-induced bone resorption[J]. Chinese Medicine (United Kingdom), 2023, 18(1), 108.
Authors:  He, Yulin;  Kam, Hiotong;  Wu, Xue;  Chen, Qian;  Lee, Simon Ming Yuen
Favorite | TC[WOS]:4 TC[Scopus]:6  IF:5.3/5.5 | Submit date：2023/09/21
Aucubin  Endothelial Cells  Medaka  Osteogenesis  Pro-angiogenesis  Zebrafish  
Huangqin Decoction ameliorates ulcerative colitis by regulating fatty acid metabolism to mediate macrophage polarization via activating FFAR4-AMPK-PPARα pathway Journal article
Li,Min yao, Wu,Yu zhu, Qiu,Jian guo, Lei,Jun xuan, Li,Mu xia, Xu,Nan, Liu,Yu hong, Jin,Zhen, Su,Zi ren, Lee,Simon Ming Yuen, Zheng,Xue bao, Xiao-qi,Huang. Huangqin Decoction ameliorates ulcerative colitis by regulating fatty acid metabolism to mediate macrophage polarization via activating FFAR4-AMPK-PPARα pathway[J]. Journal of Ethnopharmacology, 2023, 311, 116430.
Authors:  Li,Min yao;  Wu,Yu zhu;  Qiu,Jian guo;  Lei,Jun xuan;  Li,Mu xia; et al.
Favorite | TC[WOS]:13 TC[Scopus]:15  IF:4.8/4.8 | Submit date：2023/08/03
Fatty Acid Metabolism  Ffar4-ampk-pparα Pathway  Gut Microbiota  Huangqin Decoction  Macrophage Polarization  Ulcerative Colitis