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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:  Gong, Xiaoqing;  Li, Shuli;  Huang, Junli;  Tan, Shuoyan;  Zhang, Qianqian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.1 | Submit date：2024/10/10
Fingerprint  Lrrk2  Molecular Docking  Pharmacophore  Virtual Screening  Zebrafish  
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice Other
2023-08-01
Authors:  Fan XiaoQing;  Mai Chutian;  Zuo Ling;  Huang, Jumin;  Xie Chun; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/09/04
Androgen Signaling Contributes to Sex Differences in Cancer by Inhibiting NF-κB Activation in T Cells and Suppressing Antitumor Immunity Journal article
Zhang, Xiaomin, Cheng, Limin, Gao, Chengqi, Chen, Jing, Liao, Shuangye, Zheng, Yongqiang, Xu, Liping, He, Jingjing, Wang, Danyang, Fang, Ziqian, Zhang, Jianeng, Yan, Min, Luan, Yi, Chen, Siyu, Chen, Likun, Xia, Xiaojun, Deng, Chunhao, Chen, Guokai, Li, Wende, Liu, Zexian, Zhou, Penghui. Androgen Signaling Contributes to Sex Differences in Cancer by Inhibiting NF-κB Activation in T Cells and Suppressing Antitumor Immunity[J]. Cancer Research, 2023, 83(6), 906-921.
Authors:  Zhang, Xiaomin;  Cheng, Limin;  Gao, Chengqi;  Chen, Jing;  Liao, Shuangye; et al.
Favorite | TC[WOS]:21 TC[Scopus]:21  IF:12.5/11.6 | Submit date：2023/04/03
Herbal formula BWBDS alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice Journal article
Fan XiaoQing, Mai ChuTian, Zuo Ling, Huang JuMin, Xie Chun, Jiang ZeBo, Li RunZe, Yao XiaoJun, Fan XingXing, Wu QiBiao, Yan PeiYu, Liu Liang, Chen JianXin, Xie Ying, Leung Elaine Lai Han. Herbal formula BWBDS alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice[J]. Acta Pharmaceutica Sinica B, 2023, 13(3), 1164-1179.
Authors:  Fan XiaoQing;  Mai ChuTian;  Zuo Ling;  Huang JuMin;  Xie Chun; et al.
Adobe PDF | Favorite | TC[WOS]:25 TC[Scopus]:28  IF:14.7/14.1 | Submit date：2023/10/24
16s Pacbio Smrt Sequencing  Baweibaidusan  Interleukin-10  Lactobacillus Johnsonii  Macrophages  Network Pharmacology  Sepsis-induced Liver Injury  
Upgrade of Chrysomycin A as a novel Topoisomerase II inhibitor to Curb KRAS-mutant lung adenocarcinoma progression. Journal article
Zhang JunMin, Liu Pei, Chen JianWei, Yao DaHong, Liu Qing, Zhang JuanHong, Zhang HuaWei, Leung Elaine Lai Han, Yao XiaoJun, Liu Liang. Upgrade of Chrysomycin A as a novel Topoisomerase II inhibitor to Curb KRAS-mutant lung adenocarcinoma progression.[J]. Pharmacological Research, 2023.
Authors:  Zhang JunMin;  Liu Pei;  Chen JianWei;  Yao DaHong;  Liu Qing; et al.
Adobe PDF | Favorite |   IF:9.1/9.0 | Submit date：2023/10/23
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression Journal article
Zhang JunMin, Liu Pei, Chen JianWei, Yao DaHong, Liu Qing, Zhang JuanHong, Zhang Hua Wei, Leung Elaine Lai Han, Yao XiaoJun, Liu Liang. Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression[J]. Pharmacological Research, 2023, 187.
Authors:  Zhang JunMin;  Liu Pei;  Chen JianWei;  Yao DaHong;  Liu Qing; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:9.1/9.0 | Submit date：2023/02/08
Apoptosis  Chrysomycin a  Dna Damage  Reactive Oxygen Species  Topoisomerase Ii Activity  
One-step self-assembling multiple hydrophobic quantum dots and hydrophilic biomolecules into all-inclusive tags for ultrasensitive immunosensors Journal article
Guan, Tian, Shen, Yudong, Jiang, Zhuo, Liu, Yingju, Aori, Qileng, Koidis, Anastasios, Yao, Xiaojun, Lei, Hongtao. One-step self-assembling multiple hydrophobic quantum dots and hydrophilic biomolecules into all-inclusive tags for ultrasensitive immunosensors[J]. Sensors and Actuators B: Chemical, 2022, 373.
Authors:  Guan, Tian;  Shen, Yudong;  Jiang, Zhuo;  Liu, Yingju;  Aori, Qileng; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:8.0/7.0 | Submit date：2023/01/30
Hydrophobic Quantum Dots  Multiplex Immunochromatography Assay  One-step  Ped-5 Inhibitors  Self-assemble  
In Silico Study of the Acquired Resistance Caused by the Secondary Mutations of KRAS G12C Protein Using Long Time Molecular Dynamics Simulation and Markov State Model Analysis Journal article
Tu Gao, Liu Qing, Qiu Yue, Leung Elaine Lai Han, Yao XiaoJun. In Silico Study of the Acquired Resistance Caused by the Secondary Mutations of KRAS G12C Protein Using Long Time Molecular Dynamics Simulation and Markov State Model Analysis[J]. International Journal of Molecular Sciences, 2022, 23(22), 13845.
Authors:  Tu Gao;  Liu Qing;  Qiu Yue;  Leung Elaine Lai Han;  Yao XiaoJun
Favorite | TC[WOS]:6 TC[Scopus]:8 | Submit date：2023/01/31
Kras G12c Inhibitor  Drug Resistance  Molecular Dynamics  Markov State Model  
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice Journal article
Fan, Xiaoqing, Mai, Chutian, Zuo, Ling, Huang, Jumin, Xie, Chun, Jiang, Zebo, Li, Runze, Yao, Xiaojun, Fan, Xingxing, Wu, Qibiao, Yan, Peiyu, Liu, Liang, Chen, Jianxin, Xie, Ying, Elaine Lai-Han Leung. Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice[J]. Acta Pharmaceutica Sinica B, 2022, 13(3), 1164-1179.
Authors:  Fan, Xiaoqing;  Mai, Chutian;  Zuo, Ling;  Huang, Jumin;  Xie, Chun; et al.
Favorite | TC[WOS]:25 TC[Scopus]:28  IF:14.7/14.1 | Submit date：2023/01/30
16s Pacbio Smrt Sequencing  Baweibaidusan  Interleukin-10  Lactobacillus Johnsonii  Macrophages  Network Pharmacology  Sepsis-induced Liver Injury  
Novel clinical biomarkers in blood and pleural effusion for diagnosing patients with tuberculosis distinguishing from malignant tumor Journal article
Wang Jian, Feng ZheXiang, Ren Tao, Meng WeiYu, Khan Imran, Fan XingXing, Pan HuDan, Liu Liang, Tang YiJun, Yao XiaoJun, Li RunZe, Wang MeiFang, Leung Elaine Lai Han. Novel clinical biomarkers in blood and pleural effusion for diagnosing patients with tuberculosis distinguishing from malignant tumor[J]. MEDICINE, 2022, 101(41), E31027.
Authors:  Wang Jian;  Feng ZheXiang;  Ren Tao;  Meng WeiYu;  Khan Imran; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:1.3/1.6 | Submit date：2022/11/07
Biomarker  Cancerous  Diagnosis  Pleural Effusion  Tuberculous