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Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency Journal article
Zhou, Xiaoxiao, Ren, Zhili, Xu, Jiaqi, Deng, Chunhao, Zhang, Zhaoying, Godoy-Parejo, Carlos, Xu, Faxiang, Huang, Esther Chi Cheng, Wang, Jiajia, Cai, Zheyu, Liu, Weiwei, Hu, Guang, Chen, Guokai. Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency[J]. International Journal of Biological Sciences, 2022, 18(9), 3562-3575.
Authors:  Zhou, Xiaoxiao;  Ren, Zhili;  Xu, Jiaqi;  Deng, Chunhao;  Zhang, Zhaoying; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date:2022/08/05
Cell Survival  Insulin  Akt  Noxa/pmaip1  Mtor  Eif4e  Pluripotency  Proliferation  Translation  Human Pluripotent Stem Cell (Hpsc)  
Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells Journal article
Chunhao Deng, Zhaoying Zhang, Faxiang Xu, Jiaqi Xu, Zhili Ren, Carlos Godoy-Parejo, Xia Xiao, Weiwei Liu, Zhou Zhou, Guokai Chen. Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells[J]. Stem Cell Research and Therapy, 2022, 13(1).
Authors:  Chunhao Deng;  Zhaoying Zhang;  Faxiang Xu;  Jiaqi Xu;  Zhili Ren; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:7.1/7.9 | Submit date:2022/05/13
Cell Culture  Hpscs  Pluripotency  Thyroid Hormone  Triiodothyronine (T3)  Trophoblast  
Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells Journal article
Xu, Faxiang, Deng, Chunhao, Ren, Zhili, Sun, Liangyu, Meng, Ya, Liu, Weiwei, Wan, Jianbo, Chen, Guokai. Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells[J]. Cell Reports, 2021, 37(9), 110063.
Authors:  Xu, Faxiang;  Deng, Chunhao;  Ren, Zhili;  Sun, Liangyu;  Meng, Ya; et al.
Favorite | TC[WOS]:13 TC[Scopus]:13  IF:7.5/8.5 | Submit date:2021/12/08
Cellular State  Hpsc  Lipid  Lpa  Metabolism  Mitochondria  Pluripotency  Transcriptome  
Protocol for intracellular and extracellular metabolite detection in human embryonic stem cells Journal article
Xu, Faxiang, Song, Chengcheng, Liu, Weiwei, Chen, Guokai. Protocol for intracellular and extracellular metabolite detection in human embryonic stem cells[J]. STAR Protocols, 2021, 2(3), 100740.
Authors:  Xu, Faxiang;  Song, Chengcheng;  Liu, Weiwei;  Chen, Guokai
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:1.3/1.5 | Submit date:2021/12/08
Cell Culture  Cell Differentiation  Flow Cytometry/mass Cytometry  Metabolism  Metabolomics  Stem Cells  
Generation of a human induced pluripotent stem cell line (NCCDFWi001-A) from a Marfan syndrome patient carrying two FBN1 variants (c.2613A > C and c.684_736 + 4del) Journal article
Ma,Baihui, Luo,Mingyao, Yang,Hang, Li,Tianjiao, Liu,Weiwei, Xu,Faxiang, Shu,Chang, Chen,Guokai, Zhou,Zhou. Generation of a human induced pluripotent stem cell line (NCCDFWi001-A) from a Marfan syndrome patient carrying two FBN1 variants (c.2613A > C and c.684_736 + 4del)[J]. Stem Cell Research, 2020, 42, 101690.
Authors:  Ma,Baihui;  Luo,Mingyao;  Yang,Hang;  Li,Tianjiao;  Liu,Weiwei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:0.8/1.1 | Submit date:2021/03/02
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal article
Yang,Yang, Ren,Zhili, Xu,Faxiang, Meng,Ya, Zhang,Yumeng, Ai,Nana, Long,Yan, Fok,Hio Ian, Deng,Chunhao, Zhao,Xianyang, Huang,Liancheng, Zhao,Qi, Wang,Jiaxian, Liu,Weiwei, Ge,Wei, Chen,Guokai. Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells[J]. Cell Reports, 2019, 29(11), 3374-3384.e5.
Authors:  Yang,Yang;  Ren,Zhili;  Xu,Faxiang;  Meng,Ya;  Zhang,Yumeng; et al.
Favorite | TC[WOS]:17 TC[Scopus]:17  IF:7.5/8.5 | Submit date:2021/03/02
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
Chengcheng Song, Faxiang Xu, Zhili Ren, Yumeng Zhang, Ya Meng, Yiqi Yang, Shreyas Lingadahalli, Edwin Cheung, Gang Li, Weiwei Liu, Jianbo Wan, Yang Zhao, Guokai Chen. Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells[J]. STEM CELL REPORTS, 2019, 13(2), 338-351.
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng; et al.
Favorite | TC[WOS]:29 TC[Scopus]:34  IF:5.9/5.9 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation