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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:  Gong, Xiaoqing;  Li, Shuli;  Huang, Junli;  Tan, Shuoyan;  Zhang, Qianqian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.1 | Submit date：2024/10/10
Fingerprint  Lrrk2  Molecular Docking  Pharmacophore  Virtual Screening  Zebrafish  
Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer Journal article
Zhang YiZhong, Lai HuanLing, Huang Chen, Jiang ZeBo, Yan HaoXin, Wang XuanRun, Xie Chun, Huang JuMin, Ren WenKang, Li JiaXin, Zhai ZhiRan, Yao XiaoJun, Wu QiBiao, Leung Elaine Lai Han. Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer[J]. Phytomedicine, 2024, 128, 155431.
Authors:  Zhang YiZhong;  Lai HuanLing;  Huang Chen;  Jiang ZeBo;  Yan HaoXin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.7/6.2 | Submit date：2024/05/16
Er Stress  Jnk  Nfat2  Nsclc  Pd-l1  Tanshinone Iia  
Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice Other
2023-08-01
Authors:  Fan XiaoQing;  Mai Chutian;  Zuo Ling;  Huang, Jumin;  Xie Chun; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/09/04
Pharmacokinetics, absorption and transport mechanism for ginseng polysaccharides. Journal article
Zhang JuanHong, He JiaXin, Huang JuMin, Li XueFeng, Fan XiaoQing, Li WenBin, Wu GuoFan, Xie Chun, Fan XingXing, Zhang JunMin, Yao XiaoJun, Wang Rong, Leung Elaine Lai Han. Pharmacokinetics, absorption and transport mechanism for ginseng polysaccharides.[J]. Biomedicine and Pharmacotherapy, 2023.
Authors:  Zhang JuanHong;  He JiaXin;  Huang JuMin;  Li XueFeng;  Fan XiaoQing; et al.
Favorite |   IF:6.9/6.8 | Submit date：2023/06/15
Pharmacokinetics, absorption and transport mechanism for ginseng polysaccharides Journal article
Zhang JuanHong, He JiaXin, Huang JuMin, Li XueFeng, Fan XiaoQing, Li WenBin, Wu GuoFan, Xie Chun, Fan XingXing, Zhang JunMin, Yao XiaoJun, Wang Rong, Leung Elaine Lai Han. Pharmacokinetics, absorption and transport mechanism for ginseng polysaccharides[J]. Biomedicine and Pharmacotherapy, 2023, 162, 114610.
Authors:  Zhang JuanHong;  He JiaXin;  Huang JuMin;  Li XueFeng;  Fan XiaoQing; et al.
Favorite | TC[WOS]:12 TC[Scopus]:14  IF:6.9/6.8 | Submit date：2023/07/26
Absorption  Ginseng Polysaccharide  Hplc-ms/ms  Lattice Proteins  Panax Ginseng  Pharmacokinetics  
Herbal formula BWBDS alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice Journal article
Fan XiaoQing, Mai ChuTian, Zuo Ling, Huang JuMin, Xie Chun, Jiang ZeBo, Li RunZe, Yao XiaoJun, Fan XingXing, Wu QiBiao, Yan PeiYu, Liu Liang, Chen JianXin, Xie Ying, Leung Elaine Lai Han. Herbal formula BWBDS alleviates polymicrobial sepsis-induced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice[J]. Acta Pharmaceutica Sinica B, 2023, 13(3), 1164-1179.
Authors:  Fan XiaoQing;  Mai ChuTian;  Zuo Ling;  Huang JuMin;  Xie Chun; et al.
Adobe PDF | Favorite | TC[WOS]:25 TC[Scopus]:28  IF:14.7/14.1 | Submit date：2023/10/24
16s Pacbio Smrt Sequencing  Baweibaidusan  Interleukin-10  Lactobacillus Johnsonii  Macrophages  Network Pharmacology  Sepsis-induced Liver Injury  
Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy Journal article
Zhang JunMin, Zhang JuanHong, Leung Elaine Lai Han, Yao XiaoJun. Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy[J]. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2023, 32(2), 101-106.
Authors:  Zhang JunMin;  Zhang JuanHong;  Leung Elaine Lai Han;  Yao XiaoJun
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.9/5.3 | Submit date：2023/06/15
Kras G12c  Amg 510  Mrtx 849  Targeted Therapy  Drug Resistance  
Novel Anticancer Strategy by Targeting the Gut Microbial Neurotransmitter Signaling to Overcome Immunotherapy Resistance Journal article
Leung Elaine Lai Han, Huang JuMin, Zhang JunMin, Zhang JuanHong, Wang MeiFang, Zhu YingJie, Meng ZhiQiang, Yu HaiJie, Neher Erwin, Ma LiJuan, Yao XiaoJun. Novel Anticancer Strategy by Targeting the Gut Microbial Neurotransmitter Signaling to Overcome Immunotherapy Resistance[J]. ANTIOXIDANTS & REDOX SIGNALING, 2023, 38(4-6), 298-315.
Authors:  Leung Elaine Lai Han;  Huang JuMin;  Zhang JunMin;  Zhang JuanHong;  Wang MeiFang; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:5.9/10.5 | Submit date：2023/03/06
Neurotransmitters  Gut Microbiota  Tumor  Cancer Immunotherapy  
Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy. Journal article
Zhang JunMin, Zhang JuanHong, Leung Elaine Lai Han, Yao XiaoJun. Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy.[J]. Expert Opinion on Investigational Drugs, 2023.
Authors:  Zhang JunMin;  Zhang JuanHong;  Leung Elaine Lai Han;  Yao XiaoJun
Favorite |   IF:4.9/5.3 | Submit date：2023/10/23
Upgrade of Chrysomycin A as a novel Topoisomerase II inhibitor to Curb KRAS-mutant lung adenocarcinoma progression. Journal article
Zhang JunMin, Liu Pei, Chen JianWei, Yao DaHong, Liu Qing, Zhang JuanHong, Zhang HuaWei, Leung Elaine Lai Han, Yao XiaoJun, Liu Liang. Upgrade of Chrysomycin A as a novel Topoisomerase II inhibitor to Curb KRAS-mutant lung adenocarcinoma progression.[J]. Pharmacological Research, 2023.
Authors:  Zhang JunMin;  Liu Pei;  Chen JianWei;  Yao DaHong;  Liu Qing; et al.
Adobe PDF | Favorite |   IF:9.1/9.0 | Submit date：2023/10/23