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Aurora A kinase inhibition compromises its antitumor efficacy by elevating PD-L1 expression Journal article
Wang, Xiaobo, Huang, Jing, Liu, Fenglin, Yu, Qian, Wang, Ruina, Wang, Jiaqi, Zhu, Zewen, Yu, Juan, Hou, Jun, Shim, Joong Sup, Jiang, Wei, Li, Zengxia, Zhang, Yuanyuan, Dang, Yongjun. Aurora A kinase inhibition compromises its antitumor efficacy by elevating PD-L1 expression[J]. Journal of Clinical Investigation, 2023, 133(9), e161929.
Authors:  Wang, Xiaobo;  Huang, Jing;  Liu, Fenglin;  Yu, Qian;  Wang, Ruina; et al.
Favorite | TC[WOS]:16 TC[Scopus]:19  IF:13.3/14.6 | Submit date：2023/06/05
Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation Journal article
Changxiang Shi, Shishi Tao, Guowen Ren, Eun Ju Yang, Xiaodong Shu, Pui Kei Mou, Yifan Liu, Yongjun Dang, Xiaoling Xu, Joong Sup Shim. Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation[J]. Oncogene, 2022, 41(19), 2734-2748.
Authors:  Changxiang Shi;  Shishi Tao;  Guowen Ren;  Eun Ju Yang;  Xiaodong Shu; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:6.9/7.5 | Submit date：2022/05/31
Astemizole inhibits mTOR signaling and angiogenesis by blocking cholesterol trafficking Journal article
Lyu,Junfang, Yang,Eun Ju, Head,Sarah A., Ai,Nana, Zhang,Baoyuan, Wu,Changjie, Li,Ruo Jing, Liu,Yifan, Chakravarty,Harapriya, Zhang,Shaolin, Tam,Kin Yip, Dang,Yongjun, Kwon,Ho Jeong, Ge,Wei, Liu,Jun O., Shim,Joong Sup. Astemizole inhibits mTOR signaling and angiogenesis by blocking cholesterol trafficking[J]. International Journal of Biological Sciences, 2018, 14(10), 1175-1185.
Authors:  Lyu,Junfang;  Yang,Eun Ju;  Head,Sarah A.;  Ai,Nana;  Zhang,Baoyuan; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:8.2/8.3 | Submit date：2021/03/02
Angiogenesis  Astemizole  Cholesterol Trafficking  Mtor  Npc1  
Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking Journal article
Lyu, Junfang, Yang, Eun Ju, Head, Sarah A., Ai, Nana, Zhang, Baoyuan, Wu, Changjie, Li, Ruo-Jing, Liu, Yifan, Chakravarty, Harapriya, Zhang, Shaolin, Tam, Kin Yip, Dang, Yongjun, Kwon, Ho Jeong, Gel, Wei, Liu, Jun O., Shim, Joong Sup. Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 14(10), 1175-1185.
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan; et al.
Favorite | TC[WOS]:21 TC[Scopus]:22  IF:8.2/8.3 | Submit date：2018/10/30
Cholesterol Trafficking  Angiogenesis  Astemizole  Npc1  Mtor  
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
Lyu, Junfang, Yang, Eun Ju, Head, Sarah A., Ai, Nana, Zhang, Baoyuan, Wu, Changjie, Li, Ruo-Jing, Liu, Yifan, Yang, Chen, Dang, Yongjun, Kwon, Ho Jeong, Ge, Wei, Liu, Jun O., Shim, Joong Sup. Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth[J]. CANCER LETTERS, 2017, 409, 91-103.
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan; et al.
Favorite | TC[WOS]:56 TC[Scopus]:59  IF:9.1/8.3 | Submit date：2018/10/30
Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine