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Tetramethylpyrazine Nitrone (TBN) Reduces Amyloid β Deposition in Alzheimer’s Disease Models by Modulating APP Expression, BACE1 Activity, and Autophagy Pathways Journal article
Zhou, Xinhua, Zhu, Zeyu, Kuang, Shaoming, Huang, Kaipeng, Li, Yueping, Wang, Yuqiang, Chen, Haiyun, Hoi, Maggie Pui Man, Xu, Benhong, Yang, Xifei, Zhang, Zaijun. Tetramethylpyrazine Nitrone (TBN) Reduces Amyloid β Deposition in Alzheimer’s Disease Models by Modulating APP Expression, BACE1 Activity, and Autophagy Pathways[J]. Pharmaceuticals, 2024, 17(8), 1005.
Authors:  Zhou, Xinhua;  Zhu, Zeyu;  Kuang, Shaoming;  Huang, Kaipeng;  Li, Yueping; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.3/4.6 | Submit date：2024/10/10
Amyloid Precursor Protein  Amyloid β  Microrna  
Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis Journal article
Xinhua Zhou, Kaipeng Huang, Yuqiang Wang, Zaijun Zhang, Yingying Liu, Qinghua Hou, Xifei Yang, Maggie Pui Man Hoi. Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis[J]. Frontiers in Pharmacology, 2023, 14, 1082602.
Authors:  Xinhua Zhou;  Kaipeng Huang;  Yuqiang Wang;  Zaijun Zhang;  Yingying Liu; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:4.4/5.0 | Submit date：2023/08/03
Alhzheimer Disease  Amyloid Beta  Pink1  Proteomic Analysis  Tetramethylpyrazine Nitrone  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
Yue, Qian, Zhou, Xinhua, Zhang, Zaijun, Hoi, Maggie Pui Man. Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors[J]. International Journal of Molecular Sciences, 2022, 23(3), 1878.
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite | TC[WOS]:9 TC[Scopus]:11 | Submit date：2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer’s disease Journal article
Wu, Liangmiao, Zhou, Xinhua, Cao, Yiwan, Mak, Shing Hung, Zha, Ling, Li, Ning, Su, Zhiyang, Han, Yifan, Wang, Yuqiang, Man Hoi, Maggie Pui, Sun, Yewei, Zhang, Gaoxiao, Zhang, Zaijun, Yang, Xifei. Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer’s disease[J]. AGING CELL, 2021, 20(6), e13371.
Authors:  Wu, Liangmiao;  Zhou, Xinhua;  Cao, Yiwan;  Mak, Shing Hung;  Zha, Ling; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:8.0/9.7 | Submit date：2021/12/08
Alzheimer’s Disease  Cognitive Deficits  Memantine Nitrate  N-methyl-d-aspartate (Nmda) Receptors  Nitric Oxide  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
Xinhua Zhou, Anqi Wang, Liang Wang, Jianhua Yin, Li Wang, Lijun Di, Maggie Pui-Man Hoi, Luchen Shan, Xu Wu, Yuqiang Wang. A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer[J]. FRONTIERS IN PHARMACOLOGY, 2019, 10.
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang; et al.
Favorite | TC[WOS]:19 TC[Scopus]:20  IF:4.4/5.0 | Submit date：2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Memantine improves cognitive function and alters hippocampal and cortical proteome in triple transgenic mouse model of Alzheimer’s disease Journal article
Zhou,Xinhua, Wang,Liang, Xiao,Wei, Su,Zhiyang, Zheng,Chengyou, Zhang,Zaijun, Wang,Yuqiang, Xu,Benhong, Yang,Xifei, Hoi,Maggie Pui Man. Memantine improves cognitive function and alters hippocampal and cortical proteome in triple transgenic mouse model of Alzheimer’s disease[J]. Experimental Neurobiology, 2019, 28(3), 390-403.
Authors:  Zhou,Xinhua;  Wang,Liang;  Xiao,Wei;  Su,Zhiyang;  Zheng,Chengyou; et al.
Favorite | TC[WOS]:24 TC[Scopus]:27  IF:1.8/2.8 | Submit date：2021/03/01
Alzheimer’s Disease (Ad)  Mark2  Memantine  Proteomic  
Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment Journal article
Zhou, Xinhua, Xiao, Wei, Su, Zhiyang, Cheng, Jiehong, Zheng, Chengyou, Zhang, Zaijun, Wang, Yuqiang, Wang, Liang, Xu, Benhong, Li, Shupen, Yang, Xifei, Pui Man Hoi, Maggie. Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment[J]. Journal of Proteome Research, 2019, 18(4), 1542-1552.
Authors:  Zhou, Xinhua;  Xiao, Wei;  Su, Zhiyang;  Cheng, Jiehong;  Zheng, Chengyou; et al.
Favorite | TC[WOS]:33 TC[Scopus]:34  IF:3.8/4.1 | Submit date：2022/04/15
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ)  Donepezil  Pink 1  Proteomics  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
Tang, Fan, Zhou, Xinhua, Wang, Liang, Shan, Luchen, Li, Chuwen, Zhou, Hefeng, Lee, Simon Ming-Yuen, Hoi, Maggie Pui-Man. A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 820, 86-96.
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen; et al.
Favorite | TC[WOS]:34 TC[Scopus]:33  IF:4.2/4.3 | Submit date：2018/10/30
Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine Journal article
Zhou,Xinhua, Cui,Guozhen, Tseng,Hisa Hui Ling, Lee,Simon Ming Yuen, Leung,George Pak Heng, Chan,Shun Wan, Kwan,Yiu Wa, Hoi,Maggie Pui Man. Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine[J]. Evidence-based Complementary and Alternative Medicine, 2016, 2016.
Authors:  Zhou,Xinhua;  Cui,Guozhen;  Tseng,Hisa Hui Ling;  Lee,Simon Ming Yuen;  Leung,George Pak Heng; et al.
Favorite | TC[WOS]:17 TC[Scopus]:21  IF:2.650/3.014 | Submit date：2021/03/01
Synergistic effect of fenretinide and curcumin for treatment of non-small cell lung cancer Journal article
Huanxian Chen, Linmin Chen, Liang Wang, Xinhua Zhou, Judy Yuet-Wa Chan, Jingjing Li, Guozhen Cui, Simon Ming-Yuen Lee. Synergistic effect of fenretinide and curcumin for treatment of non-small cell lung cancer[J]. Cancer Biology and Therapy, 2016, 17(10), 1022-1029.
Authors:  Huanxian Chen;  Linmin Chen;  Liang Wang;  Xinhua Zhou;  Judy Yuet-Wa Chan; et al.
Favorite | TC[WOS]:9 TC[Scopus]:15 | Submit date：2018/11/06
Curcumin  Fenretinide  Grp78  Non-small Cell Lung Cancer