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Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment Journal article
Zheng, Yanfang, Wang, Chenxiang, Liu, Wenjing, Chen, Jiaying, Sun, Yibin, Chang, Dennis, Wang, Huan, Xu, Wen, Lu, Jin Jian, Zhou, Xian, Huang, Mingqing. Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment[J]. Biomedicine and Pharmacotherapy, 2024, 174, 116579.
Authors:  Zheng, Yanfang;  Wang, Chenxiang;  Liu, Wenjing;  Chen, Jiaying;  Sun, Yibin; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/6.8 | Submit date：2024/05/16
Baicalin  Diabetes-associated Cognitive Deficits  Keap1-nrf2  Neuroinflammation  Nlrp3 Inflammasome  Oxidative Stress  
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis Journal article
Qing-Xin Ji, Fei-Yan Zeng, Jian Zhou, Wen-Bin Wu, Xu-Jie Wang, Zhen Zhang, Guo-Yan Zhang, Jie Tong, Di-Yang Sun, Jia-Bao Zhang, Wen-Xiang Cao, Fu-Ming Shen, Jin-Jian Lu, Dong-Jie Li, Pei Wang. Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis[J]. Cell Death and Differentiation, 2022, 30(2), 457-474.
Authors:  Qing-Xin Ji;  Fei-Yan Zeng;  Jian Zhou;  Wen-Bin Wu;  Xu-Jie Wang; et al.
Favorite | TC[WOS]:27 TC[Scopus]:26  IF:13.7/13.7 | Submit date：2023/01/30
Oxidative Stress  Apoptosis  Receptor  Growth  Inhibition  Death  Motor  Gpx4  
基于FRP与UHPC组合的新型构件及其性能研究 Presentation
会议地点: 东莞, 中国, 会议日期: 28-30 May 2021, 报告日期: 2021-05-29
Authors:  Zeng, J.J.;  Ye, Y.Y.;  Zhou, J.k.;  Zhuge, Y.;  Quach, W. M.; et al.
Favorite |  | Submit date：2022/08/25
基于FRP与UHPC组合的新型构件及其性能研究 Conference paper
Zeng, J.J., Ye, Y.Y., ZHOU, J.K., Zhuge, Y., Quach, W. M., Liao, J.J.. 基于FRP与UHPC组合的新型构件及其性能研究[C], 东莞:东莞理工学院, 广东工业大学, 2021.
Authors:  Zeng, J.J.;  Ye, Y.Y.;  ZHOU, J.K.;  Zhuge, Y.;  Quach, W. M.; et al.
Favorite |  | Submit date：2022/08/25
Frp  Uhpc  Frp格栅  Frp筋  Frp筋混凝土结构  约束混凝土  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Liu,Xin, Zhang,Yiying, ZHOU,Guang Ju, Hou,Ying, Kong,Qi, Lu,Jin Jian, Zhang,Qingwen, Chen,Xiuping. Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 404, 115179.
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:3.3/3.6 | Submit date：2021/03/01
Emt  Metastasis  Tgf-β1  Chinese Medicine  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Cai,Cui Zan, Zhou,He Feng, Yuan,Ning Ning, Wu,Ming Yue, Lee,Simon Ming Yuen, Ren,Jiao Yan, Su,Huan Xing, Lu,Jin Jian, Chen,Xiu Ping, Li,Min, Tan,Jie Qiong, Lu,Jia Hong. Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation[J]. Phytomedicine, 2019, 61.
Authors:  Cai,Cui Zan;  Zhou,He Feng;  Yuan,Ning Ning;  Wu,Ming Yue;  Lee,Simon Ming Yuen; et al.
Favorite | TC[WOS]:34 TC[Scopus]:38  IF:6.7/6.2 | Submit date：2021/03/01
-synuclein  Harmine  Parkinson's Disease  Protein Kinase a  Ubiquitin-proteasome System  
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator Journal article
Xiao,Xiao, Li,Shuo, Zhang,Xiaoxun, Lu,Jinjian, Wang,Weiguang, Zhou,Shijia, Zhang,Jingyao, Wang,Rui, Li,Ao. HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator[J]. Toxicology and Applied Pharmacology, 2019, 373, 10-25.
Authors:  Xiao,Xiao;  Li,Shuo;  Zhang,Xiaoxun;  Lu,Jinjian;  Wang,Weiguang; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8  IF:3.3/3.6 | Submit date：2021/03/02
Breast Cancer Cells  Glucose Deprivation  Glucose-regulated Protein 78  Hhq-4  Unfolded Protein Response  
Efficient Mucosal Immunization by Mucoadhesive and pH-Sensitive Polymeric Vaccine Delivery System Journal article
Lei Xin, Tian-Jiao Zhou, Ya-Tong Fan, Yu-jing He, Tao Pang, Ki-Hyun Cho, Jin-Jian Lu, Hu-Lin Jiang, Chong-Su Cho. Efficient Mucosal Immunization by Mucoadhesive and pH-Sensitive Polymeric Vaccine Delivery System[J]. Macromolecular Research, 2019, 27(3), 215-226.
Authors:  Lei Xin;  Tian-Jiao Zhou;  Ya-Tong Fan;  Yu-jing He;  Tao Pang; et al.
Favorite | TC[WOS]:13 TC[Scopus]:14  IF:2.8/2.0 | Submit date：2019/01/15
Mucosal Immunization  Mucoadhesive Polymer  Ph-sensitive  Vaccine Delivery  m Cell Targeting  
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Anqi Wang, Fayang Zhou, Dan Li, Jin-Jian Lu, Yitao Wang, Ligen Lin. γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis[J]. Toxicology and Applied Pharmacology, 2019, 363, 142-153.
Authors:  Anqi Wang;  Fayang Zhou;  Dan Li;  Jin-Jian Lu;  Yitao Wang; et al.
Favorite | TC[WOS]:21 TC[Scopus]:24  IF:3.3/3.6 | Submit date：2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer Journal article
Wang Y., Xu X., Maglic D., Dill M.T., Mojumdar K., Ng P.K.-S., Jeong K.J., Tsang Y.H., Moreno D., Bhavana V.H., Peng X., Ge Z., Chen H., Li J., Chen Z., Zhang H., Han L., Du D., Creighton C.J., Mills G.B., Caesar-Johnson S.J., Demchok J.A., Felau I., Kasapi M., Ferguson M.L., Hutter C.M., Sofia H.J., Tarnuzzer R., Wang Z., Yang L., Zenklusen J.C., Zhang J.J., Chudamani S., Liu J., Lolla L., Naresh R., Pihl T., Sun Q., Wan Y., Wu Y., Cho J., DeFreitas T., Frazer S., Gehlenborg N., Getz G., Heiman D.I., Kim J., Lawrence M.S., Lin P., Meier S., Noble M.S., Saksena G., Voet D., Zhang H., Bernard B., Chambwe N., Dhankani V., Knijnenburg T., Kramer R., Leinonen K., Liu Y., Miller M., Reynolds S., Shmulevich I., Thorsson V., Zhang W., Akbani R., Broom B.M., Hegde A.M., Ju Z., Kanchi R.S., Korkut A., Li J., Liang H., Ling S., Liu W., Lu Y., Mills G.B., Ng K.-S., Rao A., Ryan M., Wang J., Weinstein J.N., Zhang J., Abeshouse A., Armenia J., Chakravarty D., Chatila W.K., de Bruijn I., Gao J., Gross B.E., Heins Z.J., Kundra R., La K., Ladanyi M., Luna A., Nissan M.G., Ochoa A., Phillips S.M., Reznik E., Sanchez-Vega F., Sander C., Schultz N., Sheridan R., Sumer S.O., Sun Y., Taylor B.S., Wang J., Zhang H., Anur P., Peto M., Spellman P., Benz C., Stuart J.M., Wong C.K., Yau C., Hayes D.N., Parker J.S., Wilkerson M.D., Ally A., Balasundaram M., Bowlby R., Brooks D., Carlsen R., Chuah E., Dhalla N., Holt R., Jones S.J.M., Kasaian K., Lee D., Ma Y., Marra M.A., Mayo M., Moore R.A., Mungall A.J., Mungall K., Robertson A.G., Sadeghi S., Schein J.E., Sipahimalani P., Tam A., Thiessen N., Tse K., Wong T., Berger A.C., Beroukhim R., Cherniack A.D., Cibulskis C., Gabriel S.B., Gao G.F., Ha G., Meyerson M., Schumacher S.E., Shih J., Kucherlapati M.H., Kucherlapati R.S., Baylin S., Cope L., Danilova L., Bootwalla M.S., Lai P.H., Maglinte D.T., Van Den Berg D.J., Weisenberger D.J., Auman J.T., Balu S., Bodenheimer T., Fan C., Hoadley K.A., Hoyle A.P., Jefferys S.R., Jones C.D., Meng S., Mieczkowski P.A., Mose L.E., Perou A.H., Perou C.M., Roach J., Shi Y., Simons J.V., Skelly T., Soloway M.G., Tan D., Veluvolu U., Fan H., Hinoue T., Laird P.W., Shen H., Zhou W., Bellair M., Chang K., Covington K., Creighton C.J., Dinh H., Doddapaneni H., Donehower L.A., Drummond J., Gibbs R.A., Glenn R., Hale W., Han Y., Hu J., Korchina V., Lee S., Lewis L., Li W., Liu X., Morgan M., Morton D., Muzny D., Santibanez J., Sheth M., Shinbrot E., Wang L., Wang M., Wheeler D.A., Xi L., Zhao F., Hess J., Appelbaum E.L., Bailey M., Cordes M.G., Ding L., Fronick C.C., Fulton L.A., Fulton R.S., Kandoth C., Mardis E.R., McLellan M.D., Miller C.A., Schmidt H.K., Wilson R.K., Crain D., Curley E., Gardner J., Lau K., Mallery D., Morris S., Paulauskis J., Penny R., Shelton C., Shelton T., Sherman M., Thompson E., Yena P., Bowen J., Gastier-Foster J.M., Gerken M., Leraas K.M., Lichtenberg T.M., Ramirez N.C., Wise L., Zmuda E., Corcoran N., Costello T., Hovens C., Carvalho A.L., de Carvalho A.C., Fregnani J.H., Longatto-Filho A., Reis R.M., Scapulatempo-Neto C., Silveira H.C.S., Vidal D.O., Burnette A., Eschbacher J., Hermes B., Noss A., Singh R., Anderson M.L., Castro P.D., Ittmann M., Huntsman D., Kohl B., Le X., Thorp R., Andry C., Duffy E.R., Lyadov V., Paklina O., Setdikova G., Shabunin A., Tavobilov M., McPherson C., Warnick R., Berkowitz R., Cramer D., Feltmate C., Horowitz N., Kibel A., Muto M., Raut C.P., Malykh A., Barnholtz-Sloan J.S., Barrett W., Devine K., Fulop J., Ostrom Q.T., Shimmel K., Wolinsky Y., Sloan A.E., De Rose A., Giuliante F., Goodman M., Karlan B.Y., Hagedorn C.H., Eckman J., Harr J., Myers J., Tucker K., Zach L.A., Deyarmin B., Hu H., Kvecher L., Larson C., Mural R.J., Somiari S., Vicha A., Zelinka T., Bennett J., Iacocca M., Rabeno B., Swanson P., Latour M., Lacombe L., Tetu B., Bergeron A., McGraw M., Staugaitis S.M., Chabot J., Hibshoosh H., Sepulveda A., Su T., Wang T., Potapova O., Voronina O., Desjardins L., Mariani O., Roman-Roman S., Sastre X., Stern M.-H., Cheng F., Signoretti S., Berchuck A., Bigner D., Lipp E., Marks J., McCall S., McLendon R., Secord A., Sharp A., Behera M., Brat D.J., Chen A., Delman K., Force S., Khuri F., Magliocca K., Maithel S., Olson J.J., Owonikoko T., Pickens A., Ramalingam S., Shin D.M., Sica G., Van Meir E.G., Zhang H., Eijckenboom W., Gillis A., Korpershoek E., Looijenga L., Oosterhuis W., Stoop H., van Kessel K.E., Zwarthoff E.C., Calatozzolo C., Cuppini L., Cuzzubbo S., DiMeco F., Finocchiaro G., Mattei L., Perin A., Pollo B., Chen C., Houck J., Lohavanichbutr P., Hartmann A., Stoehr C., Stoehr R., Taubert H., Wach S., Wullich B., Kycler W., Murawa D., Wiznerowicz M., Chung K., Edenfield W.J., Martin J., Baudin E., Bubley G., Bueno R., De Rienzo A., Richards W.G., Kalkanis S., Mikkelsen T., Noushmehr H., Scarpace L., Girard N., Aymerich M., Campo E., Gine E., Guillermo A.L., Van Bang N., Hanh P.T., Phu B.D., Tang Y., Colman H., Evason K., Dottino P.R., Martignetti J.A., Gabra H., Juhl H., Akeredolu T., Stepa S., Hoon D., Ahn K., Kang K.J., Beuschlein F., Breggia A., Birrer M., Bell D., Borad M., Bryce A.H., Castle E., Chandan V., Cheville J., Copland J.A., Farnell M., Flotte T., Giama N., Ho T., Kendrick M., Kocher J.-P., Kopp K., Moser C., Nagorney D., O'Brien D., O'Neill B.P., Patel T., Petersen G., Que F., Rivera M., Roberts L., Smallridge R., Smyrk T., Stanton M., Thompson R.H., Torbenson M., Yang J.D., Zhang L., Brimo F., Ajani J.A., Gonzalez A.M.A., Behrens C., Bondaruk J., Broaddus R., Czerniak B., Esmaeli B., Fujimoto J., Gershenwald J., Guo C., Lazar A.J., Logothetis C., Meric-Bernstam F., Moran C., Ramondetta L., Rice D., Sood A., Tamboli P., Thompson T., Troncoso P., Tsao A., Wistuba I., Carter C., Haydu L., Hersey P., Jakrot V., Kakavand H., Kefford R., Lee K., Long G., Mann G., Quinn M., Saw R., Scolyer R., Shannon K., Spillane A., Stretch J., Synott M., Thompson J., Wilmott J., Al-Ahmadie H., Chan T.A., Ghossein R., Gopalan A., Levine D.A., Reuter V., Singer S., Singh B., Tien N.V., Broudy T., Mirsaidi C., Nair P., Drwiega P., Miller J., Smith J., Zaren H., Park J.-W., Hung N.P., Kebebew E., Linehan W.M., Metwalli A.R., Pacak K., Pinto P.A., Schiffman M., Schmidt L.S., Vocke C.D., Wentzensen N., Worrell R., Yang H., Moncrieff M., Goparaju C., Melamed J., Pass H., Botnariuc N., Caraman I., Cernat M., Chemencedji I., Clipca A., Doruc S., Gorincioi G., Mura S., Pirtac M., Stancul I., Tcaciuc D., Albert M., Alexopoulou I., Arnaout A., Bartlett J., Engel J., Gilbert S., Parfitt J., Sekhon H., Thomas G., Rassl D.M., Rintoul R.C., Bifulco C., Tamakawa R., Urba W., Hayward N., Timmers H., Antenucci A., Facciolo F., Grazi G., Marino M., Merola R., de Krijger R., Gimenez-Roqueplo A.-P., Piche A., Chevalier S., McKercher G., Birsoy K., Barnett G., Brewer C., Farver C., Naska T., Pennell N.A., Raymond D., Schilero C., Smolenski K., Williams F., Morrison C., Borgia J.A., Liptay M.J., Pool M., Seder C.W., Junker K., Omberg L., Dinkin M., Manikhas G., Alvaro D., Bragazzi M.C., Cardinale V., Carpino G., Gaudio E., Chesla D., Cottingham S., Dubina M., Moiseenko F., Dhanasekaran R., Becker K.-F., Janssen K.-P., Slotta-Huspenina J., Abdel-Rahman M.H., Aziz D., Bell S., Cebulla C.M., Davis A., Duell R., Elder J.B., Hilty J., Kumar B., Lang J., Lehman N.L., Mandt R., Nguyen P., Pilarski R., Rai K., Schoenfield L., Senecal K., Wakely P., Hansen P., Lechan R., Powers J., Tischler A., Grizzle W.E., Sexton K.C., Kastl A., Henderson J., Porten S., Waldmann J., Fassnacht M., Asa S.L., Schadendorf D., Couce M., Graefen M., Huland H., Sauter G., Schlomm T., Simon R., Tennstedt P., Olabode O., Nelson M., Bathe O., Carroll P.R., Chan J.M., Disaia P., Glenn P., Kelley R.K., Landen C.N., Phillips J., Prados M., Simko J., Smith-McCune K., VandenBerg S., Roggin K., Fehrenbach A., Kendler A., Sifri S., Steele R., Jimeno A., Carey F., Forgie I., Mannelli M., Carney M., Hernandez B., Campos B., Herold-Mende C., Jungk C., Unterberg A., von Deimling A., Bossler A., Galbraith J., Jacobus L., Knudson M., Knutson T., Ma D., Milhem M., Sigmund R., Godwin A.K., Madan R., Rosenthal H.G., Adebamowo C., Adebamowo S.N., Boussioutas A., Beer D., Giordano T., Mes-Masson A.-M., Saad F., Bocklage T., Landrum L., Mannel R., Moore K., Moxley K., Postier R., Walker J., Zuna R., Feldman M., Valdivieso F., Dhir R., Luketich J., Pinero E.M.M., Quintero-Aguilo M., Carlotti C.G., Dos Santos J.S., Kemp R., Sankarankuty A., Tirapelli D., Catto J., Agnew K., Swisher E., Creaney J., Robinson B., Shelley C.S., Godwin E.M., Kendall S., Shipman C., Bradford C., Carey T., Haddad A., Moyer J., Peterson L., Prince M., Rozek L., Wolf G., Bowman R., Fong K.M., Yang I., Korst R., Rathmell W.K., Fantacone-Campbell J.L., Hooke J.A., Kovatich A.J., Shriver C.D., DiPersio J., Drake B., Govindan R., Heath S., Ley T., Van Tine B., Westervelt P., Rubin M.A., Lee J.I., Aredes N.D., Mariamidze A., Camargo F., Liang H.. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer[J]. Cell Reports, 2018, 25(5), 1304-1317.e5.
Authors:  Wang Y.;  Xu X.;  Maglic D.;  Dill M.T.;  Mojumdar K.; et al.
Favorite | TC[WOS]:303 TC[Scopus]:304 | Submit date：2019/01/16
Driver Mutation  Mirna Regulation  Pan-cancer Analysis  Pathway Activity  Prognostic Power  Taz  Tcga  Tumor Subtype  Yap